| Literature DB >> 24570958 |
Vincenzo Cardinale1, Maria Consiglia Bragazzi1, Guido Carpino2, Alessia Torrice1, Alice Fraveto1, Raffaele Gentile1, Vincenzo Pasqualino1, Fabio Melandro3, Camilla Aliberti4, Carlo Bastianelli4, Roberto Brunelli4, Pasquale Bartolomeo Berloco3, Eugenio Gaudio5, Domenico Alvaro6.
Abstract
Cholangiocarcinoma (CCA) is a very heterogeneous cancer from any point of view, including epidemiology, risk factors, morphology, pathology, molecular pathology, modalities of growth and clinical features. Given this heterogeneity, a uniform classification respecting the epidemiologic, pathologic and clinical needs is currently lacking. In this manuscript we discussed the different proposed classifications of CCA in relation with recent advances in pathophysiology and biology of this cancer.Entities:
Keywords: Cholangiocarcinoma (CCA); biliary cancerogenesis; biliary tree stem/progenitor cells; cells of origin; extra-hepatic CCA; hepatic stem/progenitor cells; intra-hepatic CCA
Year: 2013 PMID: 24570958 PMCID: PMC3924690 DOI: 10.3978/j.issn.2304-3881.2013.10.02
Source DB: PubMed Journal: Hepatobiliary Surg Nutr ISSN: 2304-3881 Impact factor: 7.293