Literature DB >> 24567061

Genetics: a new interpretation of genetic studies in RA.

Michel Neidhart1, Emmanuel Karouzakis1.   

Abstract

Understanding the genetics of rheumatoid arthritis (RA) is complex, multiple genes and environmental factors are involved. A new multicentre genetic study summarizes the fundamental gene polymorphisms, pathways and cell types that are related to RA and, based on this analysis, proposes new targets for RA drug treatments.

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Mesh：

Year:  2014        PMID： 24567061     DOI： 10.1038/nrrheum.2014.21

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  10 in total

Review 1.  Genome-wide association studies to advance our understanding of critical cell types and pathways in rheumatoid arthritis: recent findings and challenges.

Authors:  Dorothée Diogo; Yukinori Okada; Robert M Plenge
Journal:  Curr Opin Rheumatol       Date:  2014-01       Impact factor: 5.006

Review 2.  Rheumatoid arthritis progression mediated by activated synovial fibroblasts.

Authors:  Elena Neumann; Stephanie Lefèvre; Birgit Zimmermann; Steffen Gay; Ulf Müller-Ladner
Journal:  Trends Mol Med       Date:  2010-08-24       Impact factor: 11.951

Review 3.  Smoking, citrullination and genetic variability in the immunopathogenesis of rheumatoid arthritis.

Authors:  Lars Klareskog; Vivianne Malmström; Karin Lundberg; Leonid Padyukov; Lars Alfredsson
Journal:  Semin Immunol       Date:  2011-03-03       Impact factor: 11.130

4.  Leukocytosis in rheumatoid arthritis.

Authors:  K M Syed; R S Pinals
Journal:  J Clin Rheumatol       Date:  1996-08       Impact factor: 3.517

Review 5.  Pharmacogenomics of biological treatment in rheumatoid arthritis.

Authors:  Xi Xie; David Zhang; Jin-wei Chen; Jing Tian; Guang-hui Ling; Fen Li
Journal:  Expert Opin Biol Ther       Date:  2013-12-03       Impact factor: 4.388

6.  Coordinated effects of sequence variation on DNA binding, chromatin structure, and transcription.

Authors:  Helena Kilpinen; Sebastian M Waszak; Andreas R Gschwind; Sunil K Raghav; Robert M Witwicki; Andrea Orioli; Eugenia Migliavacca; Michaël Wiederkehr; Maria Gutierrez-Arcelus; Nikolaos I Panousis; Alisa Yurovsky; Tuuli Lappalainen; Luciana Romano-Palumbo; Alexandra Planchon; Deborah Bielser; Julien Bryois; Ismael Padioleau; Gilles Udin; Sarah Thurnheer; David Hacker; Leighton J Core; John T Lis; Nouria Hernandez; Alexandre Reymond; Bart Deplancke; Emmanouil T Dermitzakis
Journal:  Science       Date:  2013-10-17       Impact factor: 47.728

7.  Genetics of rheumatoid arthritis contributes to biology and drug discovery.

Authors:  Yukinori Okada; Di Wu; Gosia Trynka; Towfique Raj; Chikashi Terao; Katsunori Ikari; Yuta Kochi; Koichiro Ohmura; Akari Suzuki; Shinji Yoshida; Robert R Graham; Arun Manoharan; Ward Ortmann; Tushar Bhangale; Joshua C Denny; Robert J Carroll; Anne E Eyler; Jeffrey D Greenberg; Joel M Kremer; Dimitrios A Pappas; Lei Jiang; Jian Yin; Lingying Ye; Ding-Feng Su; Jian Yang; Gang Xie; Ed Keystone; Harm-Jan Westra; Tõnu Esko; Andres Metspalu; Xuezhong Zhou; Namrata Gupta; Daniel Mirel; Eli A Stahl; Dorothée Diogo; Jing Cui; Katherine Liao; Michael H Guo; Keiko Myouzen; Takahisa Kawaguchi; Marieke J H Coenen; Piet L C M van Riel; Mart A F J van de Laar; Henk-Jan Guchelaar; Tom W J Huizinga; Philippe Dieudé; Xavier Mariette; S Louis Bridges; Alexandra Zhernakova; Rene E M Toes; Paul P Tak; Corinne Miceli-Richard; So-Young Bang; Hye-Soon Lee; Javier Martin; Miguel A Gonzalez-Gay; Luis Rodriguez-Rodriguez; Solbritt Rantapää-Dahlqvist; Lisbeth Arlestig; Hyon K Choi; Yoichiro Kamatani; Pilar Galan; Mark Lathrop; Steve Eyre; John Bowes; Anne Barton; Niek de Vries; Larry W Moreland; Lindsey A Criswell; Elizabeth W Karlson; Atsuo Taniguchi; Ryo Yamada; Michiaki Kubo; Jun S Liu; Sang-Cheol Bae; Jane Worthington; Leonid Padyukov; Lars Klareskog; Peter K Gregersen; Soumya Raychaudhuri; Barbara E Stranger; Philip L De Jager; Lude Franke; Peter M Visscher; Matthew A Brown; Hisashi Yamanaka; Tsuneyo Mimori; Atsushi Takahashi; Huji Xu; Timothy W Behrens; Katherine A Siminovitch; Shigeki Momohara; Fumihiko Matsuda; Kazuhiko Yamamoto; Robert M Plenge
Journal:  Nature       Date:  2013-12-25       Impact factor: 49.962

8.  On the origin of rheumatoid arthritis: the impact of environment and genes--a population based twin study.

Authors:  Anders J Svendsen; Kirsten O Kyvik; Gunnar Houen; Peter Junker; Kaare Christensen; Lene Christiansen; Christian Nielsen; Axel Skytthe; Jacob V Hjelmborg
Journal:  PLoS One       Date:  2013-02-28       Impact factor: 3.240

Review 9.  Non-MHC risk alleles in rheumatoid arthritis and in the syntenic chromosome regions of corresponding animal models.

Authors:  Timea Besenyei; Andras Kadar; Beata Tryniszewska; Julia Kurko; Tibor A Rauch; Tibor T Glant; Katalin Mikecz; Zoltan Szekanecz
Journal:  Clin Dev Immunol       Date:  2012-12-06

10.  An immunological biomarker to predict MTX response in early RA.

Authors:  Frederique Ponchel; Vincent Goëb; Rekha Parmar; Yasser El-Sherbiny; Marjorie Boissinot; Jehan El Jawhari; Agata Burska; Edward M Vital; Stephanie Harrison; Philip G Conaghan; Elizabeth Hensor; Paul Emery
Journal:  Ann Rheum Dis       Date:  2013-08-29       Impact factor: 19.103
  10 in total
  2 in total

1.  TIM family gene polymorphism and susceptibility to rheumatoid arthritis: Systematic review and meta-analysis.

Authors:  Bahman Razi; Samira Esmaeili Reykandeh; Shahab Alizadeh; AliAkbar Amirzargar; Amene Saghazadeh; Nima Rezaei
Journal:  PLoS One       Date:  2019-02-07       Impact factor: 3.240

2.  Are programmed cell death 1 gene polymorphisms correlated with susceptibility to rheumatoid arthritis?: A meta-analysis.

Authors:  Yuming Zou; Ziteng Zhang; Yangang Liu; Denghui Liu; Weidong Xu
Journal:  Medicine (Baltimore)       Date:  2017-09       Impact factor: 1.889
  2 in total

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