Literature DB >> 24566846

Mung bean decreases plasma cholesterol by up-regulation of CYP7A1.

Yang Yao1, Liu Hao, Zhenxing Shi, Lixia Wang, Xuzhen Cheng, Suhua Wang, Guixing Ren.   

Abstract

Our results affirmed that supplementation of 1 or 2% mung bean could decrease plasma total cholesterol and triacylglycerol level. Mung bean increased mRNA 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase. Most importantly, mung bean increased not only the protein level of cholesterol-7α-hydroxylase (CYP7A1) but also mRNA CYP7A1. It was concluded that the hypocholesterolemic activity of mung bean was most probable mediated by enhancement of bile acid excretion and up-regulation of CYP7A1.

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Year:  2014        PMID： 24566846     DOI： 10.1007/s11130-014-0405-1

Source DB:  PubMed          Journal:  Plant Foods Hum Nutr        ISSN： 0921-9668            Impact factor:   3.921


  6 in total

1.  Antidiabetic activity of Mung bean extracts in diabetic KK-Ay mice.

Authors:  Yang Yao; Feng Chen; Mingfu Wang; Jiashi Wang; Guixing Ren
Journal:  J Agric Food Chem       Date:  2008-09-04       Impact factor: 5.279

2.  Non-extractable procyanidins and lignin are important factors in the bile acid binding and radical scavenging properties of cell wall material in some fruits.

Authors:  Yasunori Hamauzu; Yukari Mizuno
Journal:  Plant Foods Hum Nutr       Date:  2011-03       Impact factor: 3.921

3.  Novel angiotensin I-converting enzyme inhibitory peptides isolated from Alcalase hydrolysate of mung bean protein.

Authors:  Guan-Hong Li; Ju-Zhen Wan; Guo-Wei Le; Yong-Hui Shi
Journal:  J Pept Sci       Date:  2006-08       Impact factor: 1.905

4.  Mung bean sprout (Phaseolus aureus) nuclease and its biological and antitumor effects.

Authors:  J Soucek; J Skvor; P Poucková; J Matousek; T Slavík; J Matousek
Journal:  Neoplasma       Date:  2006       Impact factor: 2.575

5.  Microalga decreases plasma cholesterol by down-regulation of intestinal NPC1L1, hepatic LDL receptor, and HMG-CoA reductase.

Authors:  Jingnan Chen; Yue Jiang; Ka Ying Ma; Feng Chen; Zhen-Yu Chen
Journal:  J Agric Food Chem       Date:  2011-05-23       Impact factor: 5.279

6.  Mushroom tyrosinase inhibitors from mung bean (Vigna radiatae L.) extracts.

Authors:  Yang Yao; Xuzhen Cheng; Lixia Wang; Suhua Wang; Guixing Ren
Journal:  Int J Food Sci Nutr       Date:  2011-11-01       Impact factor: 3.833
  6 in total
  4 in total

1.  Hypocholesterolemic effect of quercetin-rich onion peel extract in C57BL/6J mice fed with high cholesterol diet.

Authors:  Hyun-Ju Kang; Pichiah Balasubramanian Tirupathi Pichiah; Ravichandran Vijaya Abinaya; Hee-Sook Sohn; Youn-Soo Cha
Journal:  Food Sci Biotechnol       Date:  2016-06-30       Impact factor: 2.391

Review 2.  Traditional Chinese medicine for lipid metabolism disorders.

Authors:  Yiping Li; Xiaolong Wang; Zhijie Shen
Journal:  Am J Transl Res       Date:  2017-05-15       Impact factor: 4.060

3.  Cholesterol-Lowering and Liver-Protective Effects of Cooked and Germinated Mung Beans (Vigna radiata L.).

Authors:  Lays Arnaud Rosal Lopes; Maria do Carmo de Carvalho E Martins; Luciana Melo de Farias; Ana Karolinne da Silva Brito; Geovanni de Morais Lima; Vanessa Brito Lira de Carvalho; Cristian Francisco de Carvalho Pereira; Aírton Mendes Conde Júnior; Tatiana Saldanha; José Alfredo Gomes Arêas; Kaesel Jackson Damasceno E Silva; Karoline de Macêdo Gonçalves Frota
Journal:  Nutrients       Date:  2018-06-26       Impact factor: 5.717

4.  Improvement of glucose and lipid metabolism via mung bean protein consumption: clinical trials of GLUCODIA™ isolated mung bean protein in the USA and Canada.

Authors:  Mitsutaka Kohno; Hideo Sugano; Yuhko Shigihara; Yoshiaki Shiraishi; Takayasu Motoyama
Journal:  J Nutr Sci       Date:  2018-01-14
  4 in total

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