Literature DB >> 24566816

Diabetes. Solving human β-cell development--what does the mouse say?

Alexandra E Folias1, Matthias Hebrok1.   

Abstract

A genetic analysis of patients with permanent neonatal diabetes mellitus has revealed functional conservation of transcription factors critical for β-cell development in both mouse and man. This finding supports the use of mice for modelling human disease but also highlights the need for additional human-specific studies of β-cell function.

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Year:  2014        PMID： 24566816     DOI： 10.1038/nrendo.2014.18

Source DB:  PubMed          Journal:  Nat Rev Endocrinol        ISSN： 1759-5029            Impact factor:   43.330


  10 in total

1.  Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression.

Authors:  Lei S Qi; Matthew H Larson; Luke A Gilbert; Jennifer A Doudna; Jonathan S Weissman; Adam P Arkin; Wendell A Lim
Journal:  Cell       Date:  2013-02-28       Impact factor: 41.582

2.  Sulfonylurea receptor type 1 knock-out mice have intact feeding-stimulated insulin secretion despite marked impairment in their response to glucose.

Authors:  Chiyo Shiota; Olof Larsson; Kathy D Shelton; Masakazu Shiota; Alexander M Efanov; Marianne Hoy; Jill Lindner; Suwattanee Kooptiwut; Lisa Juntti-Berggren; Jesper Gromada; Per-Olof Berggren; Mark A Magnuson
Journal:  J Biol Chem       Date:  2002-07-30       Impact factor: 5.157

Review 3.  Stem cells to pancreatic beta-cells: new sources for diabetes cell therapy.

Authors:  Tingxia Guo; Matthias Hebrok
Journal:  Endocr Rev       Date:  2009-04-23       Impact factor: 19.871

4.  Mutations in the sulfonylurea receptor gene in familial persistent hyperinsulinemic hypoglycemia of infancy.

Authors:  P M Thomas; G J Cote; N Wohllk; B Haddad; P M Mathew; W Rabl; L Aguilar-Bryan; R F Gagel; J Bryan
Journal:  Science       Date:  1995-04-21       Impact factor: 47.728

5.  Pancreatic β cell dedifferentiation as a mechanism of diabetic β cell failure.

Authors:  Chutima Talchai; Shouhong Xuan; Hua V Lin; Lori Sussel; Domenico Accili
Journal:  Cell       Date:  2012-09-14       Impact factor: 41.582

6.  Generation of pluripotent stem cells from patients with type 1 diabetes.

Authors:  René Maehr; Shuibing Chen; Melinda Snitow; Thomas Ludwig; Lisa Yagasaki; Robin Goland; Rudolph L Leibel; Douglas A Melton
Journal:  Proc Natl Acad Sci U S A       Date:  2009-08-31       Impact factor: 11.205

Review 7.  Diabetes mellitus and the β cell: the last ten years.

Authors:  Frances M Ashcroft; Patrik Rorsman
Journal:  Cell       Date:  2012-03-16       Impact factor: 41.582

8.  Maturation of human embryonic stem cell-derived pancreatic progenitors into functional islets capable of treating pre-existing diabetes in mice.

Authors:  Alireza Rezania; Jennifer E Bruin; Michael J Riedel; Majid Mojibian; Ali Asadi; Jean Xu; Rebecca Gauvin; Kavitha Narayan; Francis Karanu; John J O'Neil; Ziliang Ao; Garth L Warnock; Timothy J Kieffer
Journal:  Diabetes       Date:  2012-06-27       Impact factor: 9.337

9.  A scalable system for production of functional pancreatic progenitors from human embryonic stem cells.

Authors:  Thomas C Schulz; Holly Y Young; Alan D Agulnick; M Josephine Babin; Emmanuel E Baetge; Anne G Bang; Anindita Bhoumik; Igor Cepa; Rosemary M Cesario; Carl Haakmeester; Kuniko Kadoya; Jonathan R Kelly; Justin Kerr; Laura A Martinson; Amanda B McLean; Mark A Moorman; Janice K Payne; Mike Richardson; Kelly G Ross; Eric S Sherrer; Xuehong Song; Alistair Z Wilson; Eugene P Brandon; Chad E Green; Evert J Kroon; Olivia G Kelly; Kevin A D'Amour; Allan J Robins
Journal:  PLoS One       Date:  2012-05-18       Impact factor: 3.240

10.  Analysis of transcription factors key for mouse pancreatic development establishes NKX2-2 and MNX1 mutations as causes of neonatal diabetes in man.

Authors:  Sarah E Flanagan; Elisa De Franco; Hana Lango Allen; Michele Zerah; Majedah M Abdul-Rasoul; Julie A Edge; Helen Stewart; Elham Alamiri; Khalid Hussain; Sam Wallis; Liat de Vries; Oscar Rubio-Cabezas; Jayne A L Houghton; Emma L Edghill; Ann-Marie Patch; Sian Ellard; Andrew T Hattersley
Journal:  Cell Metab       Date:  2014-01-07       Impact factor: 27.287
  10 in total
  1 in total

1.  Effect of Sonic hedgehog pathway inhibition on PDX1 expression during pancreatic differentiation of human embryonic stem cells.

Authors:  Prasad S Pethe; Niloufer P Dumasia; Deepa Bhartiya
Journal:  Mol Biol Rep       Date:  2021-01-23       Impact factor: 2.316
  1 in total

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