Myung Jin Kim1, Kyung Yul Hur. 1. Department of Surgery, Soonchunhyang University College of Medicine, 59, Daesagwan-ro (657, Hannam-dong), Yongsan-gu, Seoul, South Korea.
Abstract
BACKGROUND: Bariatric surgery is an efficient procedure for remission of type 2 diabetes (T2DM) in morbid obesity. However, in Asian countries, mean body mass index (BMI) of T2DM patients is about 25 kg/m(2). Various data on patients undergoing gastric bypass surgery showed that control of T2DM after surgery occurs rapidly and somewhat independent to weight loss. We hypothesized that in non-obese patients with T2DM, the glycemic control would be achieved as a consequence of gastric bypass surgery. METHODS: From September 2009, the 172 patients have had laparoscopic single anastomosis gastric bypass (LSAGB) surgery. Among them, 107 patients have been followed up more than 1 year. We analyzed the dataset of these patients. Values related to diabetes were measured before and 1, 2, and 3 years after the surgery. RESULTS: The mean BMI decreased during the first year after the surgery but plateaued after that. The mean glycosylated hemoglobin level decreased continuously. The mean fasting and postglucose loading plasma glucose level also decreased. CONCLUSION: After LSAGB surgery in non-obese T2DM patients, the control of T2DM was possible safely and effectively. However, longer follow-up with matched control group is essential.
BACKGROUND: Bariatric surgery is an efficient procedure for remission of type 2 diabetes (T2DM) in morbid obesity. However, in Asian countries, mean body mass index (BMI) of T2DM patients is about 25 kg/m(2). Various data on patients undergoing gastric bypass surgery showed that control of T2DM after surgery occurs rapidly and somewhat independent to weight loss. We hypothesized that in non-obesepatients with T2DM, the glycemic control would be achieved as a consequence of gastric bypass surgery. METHODS: From September 2009, the 172 patients have had laparoscopic single anastomosis gastric bypass (LSAGB) surgery. Among them, 107 patients have been followed up more than 1 year. We analyzed the dataset of these patients. Values related to diabetes were measured before and 1, 2, and 3 years after the surgery. RESULTS: The mean BMI decreased during the first year after the surgery but plateaued after that. The mean glycosylated hemoglobin level decreased continuously. The mean fasting and postglucose loading plasma glucose level also decreased. CONCLUSION: After LSAGB surgery in non-obese T2DM patients, the control of T2DM was possible safely and effectively. However, longer follow-up with matched control group is essential.
Authors: Luigi Piazza; Francesco Ferrara; Silvana Leanza; Danilo Coco; Salvatore Sarvà; Angelo Bellia; Carla Di Stefano; Francesco Basile; Antonio Biondi Journal: Updates Surg Date: 2011-11-22
Authors: Juliana C N Chan; Vasanti Malik; Weiping Jia; Takashi Kadowaki; Chittaranjan S Yajnik; Kun-Ho Yoon; Frank B Hu Journal: JAMA Date: 2009-05-27 Impact factor: 56.272
Authors: M García-Caballero; M Valle; J M Martínez-Moreno; F Miralles; J A Toval; J M Mata; D Osorio; A Mínguez Journal: Nutr Hosp Date: 2012 Mar-Apr Impact factor: 1.057
Authors: Maurizio De Luca; Giacomo Piatto; Giovanni Merola; Jacques Himpens; Jean-Marc Chevallier; Miguel-A Carbajo; Kamal Mahawar; Alberto Sartori; Nicola Clemente; Miguel Herrera; Kelvin Higa; Wendy A Brown; Scott Shikora Journal: Obes Surg Date: 2021-05-03 Impact factor: 4.129
Authors: L Zheng; J Wu; G Wang; G Persuitte; Y Ma; L Zou; L Zhang; M Zhao; J Wang; Qin Lan; Z Liu; H Fan; J Li Journal: Eur J Clin Nutr Date: 2015-09-02 Impact factor: 4.016
Authors: Maurizio De Luca; Tiffany Tie; Geraldine Ooi; Kelvin Higa; Jacques Himpens; Miguel-A Carbajo; Kamal Mahawar; Scott Shikora; Wendy A Brown Journal: Obes Surg Date: 2018-05 Impact factor: 4.129
Authors: Matilde Rubio-Almanza; David Hervás-Marín; Rosa Cámara-Gómez; Jana Caudet-Esteban; Juan Francisco Merino-Torres Journal: Obes Surg Date: 2019-04 Impact factor: 4.129