Literature DB >> 24563160

Hepatic cysts treated with percutaneous ethanol sclerotherapy: time to extend the indications to haemorrhagic cysts and polycystic liver disease.

Julie Benzimra1, Maxime Ronot, David Fuks, Mohamed Abdel-Rehim, Annie Sibert, Olivier Farges, Valérie Vilgrain.   

Abstract

OBJECTIVES: To describe the long-term clinical and morphological outcome of symptomatic hepatic cysts treated with percutaneous ethanol sclerotherapy (PES).
METHODS: From December 2003 to September 2011, all patients with hepatic cysts undergoing PES with a follow-up after 12 months were included. Evolution of the volume of the cysts and clinical and biological data were recorded. Features of the cyst were evaluated in each patient: simple, haemorrhagic or developed on underlying polycystic liver disease (PCLD).
RESULTS: Fifty-eight cysts (median volume 666 mL) were treated in 57 patients (52 women, mean age 58 years (18-80)). Twenty-two patients (39 %) had simple hepatic cysts, 19 (33 %) had dominant cysts on PCLD and 20 had haemorrhagic cysts (34.5 %), including 4 with PCLD. After a mean 27.3 months of follow-up, the final median cystic volume was 13.5 mL (p < 0.0001), and the median reduction in cyst volume was 94 % (58-100 %). Treatment was satisfactory in 95 % of the patients (54/57) (symptoms disappeared in 45/57 (79 %), decreased in 9/57 (16 %)). There was no clinical or morphological difference between patients with PCLD, haemorrhagic cysts or simple cysts.
CONCLUSION: The clinical and morphological efficacy of a single session of PES is very high, regardless of the presence of intracystic haemorrhage or underlying PCLD. KEY POINTS: • The clinical efficacy of percutaneous ethanol sclerotherapy is very high. • Haemorrhagic content should not be a contraindication for percutaneous sclerotherapy. • Dominant cysts on polycystic liver disease should be treated with PES. • Imaging follow-up should not be performed shortly after the procedure.

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Year:  2014        PMID: 24563160     DOI: 10.1007/s00330-014-3117-x

Source DB:  PubMed          Journal:  Eur Radiol        ISSN: 0938-7994            Impact factor:   5.315


  47 in total

1.  Large cystic lesions of the liver in adults: a 15-year experience in a tertiary center.

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Journal:  J Am Coll Surg       Date:  2001-07       Impact factor: 6.113

2.  Extended liver resection for polycystic liver disease can challenge liver transplantation.

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3.  Laparoscopic fenestration in combination with ethanol sclerotherapy prevents a recurrence of symptomatic giant liver cyst.

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Journal:  Surg Laparosc Endosc       Date:  1998-12

4.  Laparoscopic treatment of nonparasitic liver cysts: adequate selection of patients and surgical technique.

Authors:  J F Gigot; M Legrand; G Hubens; L de Canniere; E Wibin; F Deweer; M L Druart; C Bertrand; H Devriendt; R Droissart; M Tugilimana; P Hauters; L Vereecken
Journal:  World J Surg       Date:  1996-06       Impact factor: 3.352

5.  Hepatic cysts: treatment with alcohol.

Authors:  W J Bean; B A Rodan
Journal:  AJR Am J Roentgenol       Date:  1985-02       Impact factor: 3.959

Review 6.  Hemorrhagic hepatic cyst: report of a case and review of the literature with emphasis on clinical approach and management.

Authors:  Zhi Ven Fong; Andrea M Wolf; Cataldo Doria; Adam C Berger; Ernest L Rosato; Francesco Palazzo
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7.  Cystic focal liver lesions in the adult: differential CT and MR imaging features.

Authors:  K J Mortelé; P R Ros
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8.  Percutaneous aspiration and ethanolamine oleate sclerotherapy for sustained resolution of symptomatic polycystic liver disease: an initial experience.

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9.  Ethanol-induced coma after therapeutic ethanol injection of a hepatic cyst.

Authors:  Anne Wernet; Annie Sibert; Catherine Paugam-Burtz; Arnaud Geffroy; Sebastian Pease; Jacques Belghiti; Valérie Vilgrain; Jean Mantz
Journal:  Anesthesiology       Date:  2008-02       Impact factor: 7.892

10.  Clinical profile of autosomal dominant polycystic liver disease.

Authors:  Qi Qian; Airong Li; Bernard F King; Patrick S Kamath; Donna J Lager; John Huston; Clarence Shub; Sonia Davila; Stefan Somlo; Vicente E Torres
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  14 in total

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Authors:  Tiarah Simon; Ilsalien S Bakker; Luit Penninga; David R Nellensteijn
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Review 2.  Polycystic Liver Disease: Pathophysiology, Diagnosis and Treatment.

Authors:  Luiz Fernando Norcia; Erika Mayumi Watanabe; Pedro Tadao Hamamoto Filho; Claudia Nishida Hasimoto; Leonardo Pelafsky; Walmar Kerche de Oliveira; Ligia Yukie Sassaki
Journal:  Hepat Med       Date:  2022-09-29

3.  Aspiration sclerotherapy combined with pasireotide to improve reduction of large symptomatic hepatic cysts (SCLEROCYST): study protocol for a randomized controlled trial.

Authors:  Titus F M Wijnands; Tom J G Gevers; Leo J Schultze Kool; Joost P H Drenth
Journal:  Trials       Date:  2015-03-07       Impact factor: 2.279

4.  Single-session alcohol sclerotherapy of symptomatic liver cysts using 10-20 min of ethanol exposure: no recurrence at 2-16 years of follow-up.

Authors:  Trond Bjerke Larssen; Asgaut Viste; Arild Horn; Ingfrid Salvesen Haldorsen; Ansgar Espeland
Journal:  Abdom Radiol (NY)       Date:  2016-09

5.  Percutaneous Salivary Gland Ablation using Ethanol in a Rat Model.

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6.  Pasireotide does not improve efficacy of aspiration sclerotherapy in patients with large hepatic cysts, a randomized controlled trial.

Authors:  Titus F M Wijnands; Tom J G Gevers; Marten A Lantinga; René H Te Morsche; Leo J Schultze Kool; Joost P H Drenth
Journal:  Eur Radiol       Date:  2018-01-09       Impact factor: 5.315

7.  Symptom relief and not cyst reduction determines treatment success in aspiration sclerotherapy of hepatic cysts.

Authors:  Myrte K Neijenhuis; Titus F M Wijnands; Wietske Kievit; Maxime Ronot; Tom J G Gevers; Joost P H Drenth
Journal:  Eur Radiol       Date:  2018-12-12       Impact factor: 5.315

8.  Evaluation of the utility value of percutaneous drainage of symptomatic hepatic cysts combined with an obliteration attempt.

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9.  Predictors of treatment response following aspiration sclerotherapy of hepatic cysts: an international pooled analysis of individual patient data.

Authors:  Titus F M Wijnands; Maxime Ronot; Tom J G Gevers; Julie Benzimra; Leo J Schultze Kool; Valérie Vilgrain; Joost P H Drenth
Journal:  Eur Radiol       Date:  2016-05-14       Impact factor: 5.315

10.  Ethanol sclerotherapy or polidocanol sclerotherapy for symptomatic hepatic cysts.

Authors:  Titus Fm Wijnands; Bastian Schoenemeier; Andrej Potthoff; Tom Jg Gevers; Hans Groenewoud; Michael J Gebel; Kinan Rifai; Michael P Manns; Joost Ph Drenth
Journal:  United European Gastroenterol J       Date:  2018-03-08       Impact factor: 4.623

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