Literature DB >> 24561816

Physiological responses to diesel exhaust exposure are modified by cycling intensity.

Luisa V Giles1, Jason P Brandenburg, Christopher Carlsten, Michael S Koehle.   

Abstract

BACKGROUND: Outdoor exercisers are frequently exposed to diesel exhaust (DE) that contains particulate matter (PM) air pollution. How the respiratory and metabolic responses to exercise are affected by DE exposure and how these responses change with exercise intensity are unknown.
PURPOSE: This study aimed to determine the respiratory and metabolic responses to low- and high-intensity cycling with DE exposure containing high levels of PM.
METHODS: Eighteen males age 24.5 ± 6.2 yr performed 30-min trials of low-intensity (30% of power at V˙O2peak) and high-intensity (60% of power at V˙O2peak) cycling as well as rest. Each trial was performed once while breathing filtered air (FA) and once while breathing DE (300 μg·m of PM2.5) for a total of six trials, each separated by 7 d. During the trials, minute ventilation (V˙E), oxygen consumption (V˙O2), CO2 production (V˙CO2), RER, and perceived exertion for lungs (RPELungs) and legs (RPELegs) were measured. Work of breathing, respiratory muscle V˙O2, ratio of O2 consumption to power output, and gross efficiency were estimated.
RESULTS: The RER was significantly lower (0.02 lower, P = 0.008), and the RPELungs (0.9 greater, P = 0.001) and the RPELegs (0.6 greater, P = 0.017) were significantly greater, in DE compared with FA. During low-intensity exercise, V˙E (44.5 ± 8.9 vs 40.5 ± 8.0 L·min, P < 0.001), V˙O2 (27.9 ± 5.4 vs 24.9 ± 4.4 mL·kg·min, P = 0.001), and V˙CO2 (25.9 ± 5.3 vs 23.5 ± 4.5 mL·kg·min, P = 0.006) were significantly greater in DE. This pattern was not seen during high-intensity cycling.
CONCLUSIONS: Respiratory and metabolic responses to low-intensity, but not high-intensity, cycling in DE exceed FA. Practically, the greater responses during low-intensity exercise in DE could have implications for individuals with cardiopulmonary disease. Also, the elevated RPE during DE could impair performance in self-paced exercise.

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Year:  2014        PMID: 24561816     DOI: 10.1249/MSS.0000000000000309

Source DB:  PubMed          Journal:  Med Sci Sports Exerc        ISSN: 0195-9131            Impact factor:   5.411


  14 in total

1.  The Acute Effects of Exercising in Air Pollution: A Systematic Review of Randomized Controlled Trials.

Authors:  Andy Hung; Hannah Nelson; Michael S Koehle
Journal:  Sports Med       Date:  2021-09-09       Impact factor: 11.928

Review 2.  Acute effects of short-term exposure to air pollution while being physically active, the potential for modification: A review of the literature.

Authors:  Stephanie DeFlorio-Barker; Danelle T Lobdell; Susan L Stone; Tegan Boehmer; Kristen M Rappazzo
Journal:  Prev Med       Date:  2020-07-09       Impact factor: 4.018

3.  Exercising in polluted areas: study suggests benefits outweigh the health risks of NO2 exposure.

Authors:  Nancy Averett
Journal:  Environ Health Perspect       Date:  2015-06       Impact factor: 9.031

4.  The effect of low and high-intensity cycling in diesel exhaust on flow-mediated dilation, circulating NOx, endothelin-1 and blood pressure.

Authors:  Luisa V Giles; Scott J Tebbutt; Christopher Carlsten; Michael S Koehle
Journal:  PLoS One       Date:  2018-02-21       Impact factor: 3.240

5.  Short-Term Effects of Carbonaceous Components in PM2.5 on Pulmonary Function: A Panel Study of 37 Chinese Healthy Adults.

Authors:  Shichun Huang; Huan Feng; Shanshan Zuo; Jingling Liao; Mingquan He; Masayuki Shima; Kenji Tamura; Yang Li; Lu Ma
Journal:  Int J Environ Res Public Health       Date:  2019-06-26       Impact factor: 3.390

6.  Effects of low-intensity and high-intensity cycling with diesel exhaust exposure on soluble P-selectin, E-selectin, I-CAM-1, VCAM-1 and complete blood count.

Authors:  Luisa V Giles; Scott J Tebbutt; Christopher Carlsten; Michael S Koehle
Journal:  BMJ Open Sport Exerc Med       Date:  2019-11-24

Review 7.  Respiratory Effects of Exposure to Traffic-Related Air Pollutants During Exercise.

Authors:  Giuseppe Morici; Fabio Cibella; Annalisa Cogo; Paolo Palange; Maria R Bonsignore
Journal:  Front Public Health       Date:  2020-12-11

Review 8.  Controlled human exposure to diesel exhaust: a method for understanding health effects of traffic-related air pollution.

Authors:  Erin Long; Carley Schwartz; Christopher Carlsten
Journal:  Part Fibre Toxicol       Date:  2022-02-25       Impact factor: 9.400

Review 9.  When physical activity meets the physical environment: precision health insights from the intersection.

Authors:  Luisa V Giles; Michael S Koehle; Brian E Saelens; Hind Sbihi; Chris Carlsten
Journal:  Environ Health Prev Med       Date:  2021-06-30       Impact factor: 3.674

10.  Low levels of fine particulate matter increase vascular damage and reduce pulmonary function in young healthy adults.

Authors:  Lauren H Wyatt; Robert B Devlin; Ana G Rappold; Martin W Case; David Diaz-Sanchez
Journal:  Part Fibre Toxicol       Date:  2020-11-16       Impact factor: 9.400

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