Ali F Jon1, Ahmad R Cheema1, Atif N Khan1, Vassilios Raptopoulos1, Thomas Hauser1, Imad Nasser1, Francine K Welty1, Andrew Karellas2, Melvin E Clouse3. 1. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. 2. Department of Radiology, University of Massachusetts Medical School, Worcester, MA, USA. 3. Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. Electronic address: mclouse1@bidmc.harvard.edu.
Abstract
OBJECTIVE: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). METHODS: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. RESULTS: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). CONCLUSION: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
OBJECTIVE: To develop a simplified method to quantify liver fat using computed tomography (CT) fat % index (CTFPI) compared to liver spleen method (CTL/S, CTL-S). METHODS: Noncontrast CT of the liver was performed in 89 patients (overweight, obese, severely obese) to quantify fat, using the following: CTFPI=[(65-patient HU)/65]×100, normal live r=65 HU. RESULTS: There was a strong linear correlation between CTFPI and the standard method of assessing liver fat using CTL/S (r=-0.901), CTL-S (r=-0.911). Hepatic HU and CTFPI were significantly different in the severely obese group compared to other two groups (P<.05). CONCLUSION: Significant correlation indicates equal diagnostic accuracy of the two methods in appropriately calibrated scanners.
Authors: Faisal Khosa; Atif N Khan; Khurram Nasir; Arash Bedayat; Zehra Malik; Ali F Jon; Ahmad R Cheema; Melvin E Clouse; Francine K Welty Journal: Atherosclerosis Date: 2012-12-13 Impact factor: 5.162
Authors: Piyaporn Limanond; Steven S Raman; Charles Lassman; James Sayre; R Mark Ghobrial; Ronald W Busuttil; Sammy Saab; David S K Lu Journal: Radiology Date: 2004-01 Impact factor: 11.105