Literature DB >> 24556157

Medical and nonmedical use of prescription benzodiazepine anxiolytics among U.S. high school seniors.

Sean Esteban McCabe1, Brady T West2.   

Abstract

OBJECTIVES: To examine the lifetime prevalence of medical and nonmedical use of prescription benzodiazepine anxiolytics among U.S. high school seniors and to assess substance use behaviors based on lifetime histories of medical and nonmedical use of prescription benzodiazepine anxiolytics.
METHODS: Nationally representative samples of high school seniors were surveyed during their senior year via self-administered questionnaires. The sample consisted of 11,248 high school seniors (modal age, 18years) from five independent cohorts (2007-2011). The sample was 52% female, 65% White, 12% African American, 15% Hispanic, and 7% other.
RESULTS: The lifetime prevalence of medical use of prescription benzodiazepine anxiolytics was 4.9%, while the lifetime prevalence of nonmedical use was 7.5%. Although lifetime prevalence rates were relatively stable over time, there were notable sex and racial/ethnic differences in medical and nonmedical use behaviors. Among those who were ever prescribed benzodiazepine anxiolytics (n=530), approximately 40.6% reported medical use only, 27.4% reported medical use prior to nonmedical use, and 32.0% reported nonmedical use prior to medical use. The odds of substance use behaviors were greater among those who reported any history of nonmedical use relative to non-users, while the odds of substance use behaviors did not differ between medical users only and non-users.
CONCLUSIONS: One in every ten U.S. high school seniors has ever had some exposure to prescription benzodiazepine anxiolytics either medically or nonmedically. Benzodiazepine anxiolytics prescribed to adolescents should be closely monitored, safely stored, and properly disposed to reduce nonmedical use due to leftover medication and peer diversion.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Adolescents; Benzodiazepines; Medical use; Nonmedical use; Prescription drugs; Tranquilizers

Mesh:

Substances:

Year:  2014        PMID: 24556157      PMCID: PMC4312492          DOI: 10.1016/j.addbeh.2014.01.009

Source DB:  PubMed          Journal:  Addict Behav        ISSN: 0306-4603            Impact factor:   3.913


  10 in total

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3.  Correlates of nonmedical use of prescription benzodiazepine anxiolytics: results from a national survey of U.S. college students.

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5.  Medical and nonmedical use of prescription drugs among secondary school students.

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Authors: 
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Review 9.  Benzodiazepine self-administration in humans and laboratory animals--implications for problems of long-term use and abuse.

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10.  Does early onset of non-medical use of prescription drugs predict subsequent prescription drug abuse and dependence? Results from a national study.

Authors:  Sean E McCabe; Brady T West; Michele Morales; James A Cranford; Carol J Boyd
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  10 in total
  20 in total

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3.  The epidemiology of benzodiazepine misuse: A systematic review.

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5.  Sex differences in nonmedical prescription tranquilizer and stimulant use trends among secondary school students in Argentina, Chile, and Uruguay.

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7.  Recruitment, Follow-Up and Characteristics of HIV Infected Adults who Use Illicit Drugs in Southern Africa.

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Journal:  J Drug Abuse       Date:  2015-12-08

8.  Medical and nonmedical use of prescription sedatives and anxiolytics: Adolescents' use and substance use disorder symptoms in adulthood.

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9.  Benzodiazepine use as an independent risk factor for HIV infection in a Canadian setting.

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10.  Prescription Benzodiazepine Use in Privately Insured U.S. Children and Adolescents.

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