Literature DB >> 2454007

Proteolytic degradation of desmosomes in plantar stratum corneum leads to cell dissociation in vitro.

T Egelrud1, P A Hofer, A Lundström.   

Abstract

Pieces of plantar stratum corneum were incubated with trypsin. This resulted in cell dissociation. The only observable ultrastructural change caused by trypsin was a degradation of desmosomal plates between dissociating cells. This suggests that desmosomes are of primary importance in plantar stratum corneum cell adhesion.

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Year:  1988        PMID： 2454007

Source DB:  PubMed          Journal:  Acta Derm Venereol        ISSN： 0001-5555            Impact factor:   4.437


  8 in total

1.  Desmosomes, corneosomes and desquamation. An ultrastructural study of adult pig epidermis.

Authors:  S J Chapman; A Walsh
Journal:  Arch Dermatol Res       Date:  1990       Impact factor: 3.017

2.  Kallikrein-related peptidase-8 (KLK8) is an active serine protease in human epidermis and sweat and is involved in a skin barrier proteolytic cascade.

Authors:  Azza Eissa; Vanessa Amodeo; Christopher R Smith; Eleftherios P Diamandis
Journal:  J Biol Chem       Date:  2010-10-12       Impact factor: 5.157

3.  Detection and characterization of endogenous protease associated with desquamation of stratum corneum.

Authors:  Y Suzuki; J Nomura; J Hori; J Koyama; M Takahashi; I Horii
Journal:  Arch Dermatol Res       Date:  1993       Impact factor: 3.017

Review 4.  Pathobiology of the stratum corneum.

Authors:  S M Jackson; M L Williams; K R Feingold; P M Elias
Journal:  West J Med       Date:  1993-03

5.  Lipids, proteins and corneocyte adhesion.

Authors:  S J Chapman; A Walsh; S M Jackson; P S Friedmann
Journal:  Arch Dermatol Res       Date:  1991       Impact factor: 3.017

6.  Chymotryptic specificity determinants in the 1.0 A structure of the zinc-inhibited human tissue kallikrein 7.

Authors:  Mekdes Debela; Petra Hess; Viktor Magdolen; Norman M Schechter; Thomas Steiner; Robert Huber; Wolfram Bode; Peter Goettig
Journal:  Proc Natl Acad Sci U S A       Date:  2007-10-01       Impact factor: 11.205

7.  Effect of Productive Human Papillomavirus 16 Infection on Global Gene Expression in Cervical Epithelium.

Authors:  Sa Do Kang; Sreejata Chatterjee; Samina Alam; Anna C Salzberg; Janice Milici; Sjoerd H van der Burg; Craig Meyers
Journal:  J Virol       Date:  2018-09-26       Impact factor: 5.103

Review 8.  Recommendations from a European Roundtable Meeting on Best Practice Healthy Infant Skin Care.

Authors:  Ulrike Blume-Peytavi; Tina Lavender; Dorota Jenerowicz; Irina Ryumina; Jean-Francois Stalder; Antonio Torrelo; Michael J Cork
Journal:  Pediatr Dermatol       Date:  2016-02-26       Impact factor: 1.588
  8 in total

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