Literature DB >> 24535376

Registry in Germany focusing on level-specific and evidence-based decision finding in the treatment of heart failure: REFLECT-HF.

Ulrich Tebbe1, Carsten Tschöpe, Jost Henner Wirtz, Jan Lokies, Eva Turgonyi, Peter Bramlage, Anke M Strunz, Katharina Lins, Michael Böhm.   

Abstract

BACKGROUND: In Germany, care for patients with chronic heart failure (HF) is provided by hospital-based cardiologists (HBC), office-based cardiologists (OBC) and general practitioners (GP). We aimed to compare patient characteristics, diagnostic approaches and therapeutic decisions.
METHODS: Multi-centre, cross-sectional, observational survey at 48 physicians. Patients (n = 384) were required to have previously diagnosed HF and NYHA class ≥ II and/or a left ventricular ejection fraction of <50 %. A total of 384 patients were included at 5 HBCs, 26 OBCs and 18 GPs.
RESULTS: A mean of 18.8 % of all patients at HBCs practices had heart failure, compared to a smaller proportion of 13.9 and 6.7 % at OBCs and GPs, respectively. Echo facility was available for all HBCs and OBCs, but for 16.7 % of GPs (p < 0.0001 for trend). Patients at HBCs had a higher NYHA class (65.6 % had class III/IV; p < 0.0001) compared to 36.8 % at OBCs and 39.3 % at GPs. Usage of three guideline-recommended pharmaceutical treatments was more than 80 %: diuretics (83.1 %), renin-angiotensin system blocking agents (91.4 %) and betablockers (90.1 %) with no differences between physician groups. Mineralocorticoid receptor antagonists (MRAs, overall 47.7 %) were more frequently prescribed by OBCs (54.7 %; p = 0.0007 for trend) than HBCs (43.8 %) and GPs (31.0 %). Ivabradin was not frequently used (11.0 % at OBCs, 4.9 % at HBCs and 0 % at GPs; p = 0.0163 for trend). The proportion of patients with CRT (8.6 %), ICD (23.5 %) and CABG (23.1 %) was not statistically different between groups.
CONCLUSION: REFLECT-HF demonstrates that there are some differences in evidence-based treatment decisions between the three main health services (HBC, OBC and GP) providing care for patients with HF in Germany. Advocating adherence to guideline recommendations and earlier adoption of these evidence-based treatments across all levels of care might further improve patient care.

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Year:  2014        PMID: 24535376     DOI: 10.1007/s00392-014-0678-2

Source DB:  PubMed          Journal:  Clin Res Cardiol        ISSN: 1861-0684            Impact factor:   5.460


  33 in total

1.  Diagnosis and management of heart failure: a questionnaire among general practitioners and cardiologists.

Authors:  Frans H Rutten; Diederick E Grobbee; Arno W Hoes
Journal:  Eur J Heart Fail       Date:  2003-06       Impact factor: 15.534

2.  Physicians' views on joint treatment guidelines for primary and secondary care.

Authors:  W N Kasje; P Denig; P A De Graeff; F M Haaijer-Ruskamp
Journal:  Int J Qual Health Care       Date:  2004-06       Impact factor: 2.038

3.  Eplerenone in patients with systolic heart failure and mild symptoms.

Authors:  Faiez Zannad; John J V McMurray; Henry Krum; Dirk J van Veldhuisen; Karl Swedberg; Harry Shi; John Vincent; Stuart J Pocock; Bertram Pitt
Journal:  N Engl J Med       Date:  2010-11-14       Impact factor: 91.245

4.  A propensity score analysis of the impact of angiotensin-converting enzyme inhibitors on long-term survival of older adults with heart failure and perceived contraindications.

Authors:  Ali Ahmed; Robert M Centor; Michael T Weaver; Gilbert J Perry
Journal:  Am Heart J       Date:  2005-04       Impact factor: 4.749

5.  Cross-cultural adaptation of the Minnesota Living with Heart Failure Questionnaire for German-speaking patients.

Authors:  M Quittan; G F Wiesinger; R Crevenna; M J Nuhr; M Posch; M Hülsmann; D Müller; R Pacher; V Fialka-Moser
Journal:  J Rehabil Med       Date:  2001-07       Impact factor: 2.912

6.  Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction.

Authors:  Bertram Pitt; Willem Remme; Faiez Zannad; James Neaton; Felipe Martinez; Barbara Roniker; Richard Bittman; Steve Hurley; Jay Kleiman; Marjorie Gatlin
Journal:  N Engl J Med       Date:  2003-03-31       Impact factor: 91.245

7.  Safety and costs of initiating angiotensin converting enzyme inhibitors for heart failure in primary care: analysis of individual patient data from studies of left ventricular dysfunction.

Authors:  J Mason; P Young; N Freemantle; R Hobbs
Journal:  BMJ       Date:  2000-11-04

8.  Efficacy, safety and tolerability of beta-adrenergic blockade with metoprolol CR/XL in elderly patients with heart failure.

Authors:  Prakash C Deedwania; Stephen Gottlieb; Jalal K Ghali; Finn Waagstein; John C M Wikstrand
Journal:  Eur Heart J       Date:  2004-08       Impact factor: 29.983

9.  Survival benefits of angiotensin-converting enzyme inhibitors in older heart failure patients with perceived contraindications.

Authors:  Ali Ahmed; Catarina I Kiefe; Richard M Allman; Richard V Sims; James F DeLong
Journal:  J Am Geriatr Soc       Date:  2002-10       Impact factor: 5.562

10.  Influence of gender of physicians and patients on guideline-recommended treatment of chronic heart failure in a cross-sectional study.

Authors:  Magnus Baumhäkel; Ulrike Müller; Michael Böhm
Journal:  Eur J Heart Fail       Date:  2009-01-21       Impact factor: 15.534

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  14 in total

1.  Substernal lead implantation: a novel option to manage DFT failure in S-ICD patients.

Authors:  M Guenther; S Kolschmann; M Knaut
Journal:  Clin Res Cardiol       Date:  2014-10-02       Impact factor: 5.460

2.  Guideline-led prescribing to ambulatory heart failure patients in a cardiology outpatient service.

Authors:  Seif El Hadidi; Carl Vaughan; David Kerins; Stephen Byrne; Ebtissam Darweesh; Margaret Bermingham
Journal:  Int J Clin Pharm       Date:  2021-01-07

Review 3.  A real-world perspective on the prevalence and treatment of heart failure with a reduced ejection fraction but no specific or only mild symptoms.

Authors:  Farzin Beygui; Manuel Anguita; Ulrich Tebbe; Josep Comin-Colet; Michel Galinier; Peter Bramlage; Eva Turgonyi; Katharina Lins; Lynda Imekraz; Trinidad de Frutos; Michael Böhm
Journal:  Heart Fail Rev       Date:  2015-09       Impact factor: 4.214

4.  Gender aspects in clinical presentation and prognostication of chronic heart failure according to NT-proBNP and the Heart Failure Survival Score.

Authors:  Jennifer Franke; Andreas Lindmark; Matthias Hochadel; Christian Zugck; Eva Koerner; Jeannette Keppler; Philipp Ehlermann; Ralph Winkler; Ralf Zahn; Hugo A Katus; Jochen Senges; Lutz Frankenstein
Journal:  Clin Res Cardiol       Date:  2014-11-06       Impact factor: 5.460

5.  Analyses of drugs stored at home by elderly patients with chronic heart failure.

Authors:  Sebastian Ewen; Tanja Baumgarten; Volker Rettig-Ewen; Felix Mahfoud; Nina Griese-Mammen; Martin Schulz; Michael Böhm; Ulrich Laufs
Journal:  Clin Res Cardiol       Date:  2014-11-06       Impact factor: 5.460

Review 6.  [Chronic heart failure : current guideline recommendations and innovations].

Authors:  S Ewen; F Mahfoud; M Böhm
Journal:  Internist (Berl)       Date:  2015-07       Impact factor: 0.743

7.  Effects of spironolactone on ventricular-arterial coupling in patients with chronic systolic heart failure and mild symptoms.

Authors:  Enrico Vizzardi; Edoardo Sciatti; Ivano Bonadei; Antonio D'Aloia; Lamia Tartière-Kesri; Jean-Michel Tartière; Alain Cohen-Solal; Marco Metra
Journal:  Clin Res Cardiol       Date:  2015-06-10       Impact factor: 5.460

8.  ICD therapy for primary prevention of sudden cardiac death after Mustard repair for d-transposition of the great arteries.

Authors:  David Backhoff; Matthias Müller; Wolfgang Ruschewski; Thomas Paul; Ulrich Krause
Journal:  Clin Res Cardiol       Date:  2014-05-29       Impact factor: 5.460

9.  Heart failure and the holidays.

Authors:  Mahek Shah; Vikas Bhalla; Soumya Patnaik; Obiora Maludum; Marvin Lu; Vincent M Figueredo
Journal:  Clin Res Cardiol       Date:  2016-05-24       Impact factor: 5.460

10.  General practitioners' adherence to chronic heart failure guidelines regarding medication: the GP-HF study.

Authors:  Marc N Hirt; Aljosha Muttardi; Thomas M Helms; Hendrik van den Bussche; Thomas Eschenhagen
Journal:  Clin Res Cardiol       Date:  2015-11-09       Impact factor: 5.460

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