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Literature DB >> 24534751

Glycan arrays as tools for infectious disease research.

Andreas Geissner¹, Chakkumkal Anish², Peter H Seeberger³.

Abstract

Infectious diseases cause millions of deaths worldwide each year and are a major burden for economies, especially in underdeveloped countries. Glycans and their interactions with other biomolecules are involved in all major steps of infection. Glycan arrays enable the rapid and sensitive detection of those interactions and are among the most powerful techniques to study the molecular biology of infectious diseases. This review will focus on recent developments and discuss the applications of glycan arrays to the elucidation of host-pathogen and pathogen-pathogen interactions, the development of tools for infection diagnosis and the use of glycan arrays in modern vaccine design.

Entities: Chemical Disease

Mesh：

Substances：
Polysaccharides

Year: 2013 PMID： 24534751 DOI： 10.1016/j.cbpa.2013.11.013

Source DB: PubMed Journal: Curr Opin Chem Biol ISSN： 1367-5931 Impact factor: 8.822

Keyword Cloud
Cited

28 in total

1. Combining 3D structure with glycan array data provides insight into the origin of glycan specificity.

Authors: Oliver C Grant; Matthew B Tessier; Lawrence Meche; Lara K Mahal; Bethany L Foley; Robert J Woods
Journal: Glycobiology Date: 2016-02-23 Impact factor: 4.313

2. Improving vaccines against Streptococcus pneumoniae using synthetic glycans.

Authors: Paulina Kaplonek; Naeem Khan; Katrin Reppe; Benjamin Schumann; Madhu Emmadi; Marilda P Lisboa; Fei-Fei Xu; Adam D J Calow; Sharavathi G Parameswarappa; Martin Witzenrath; Claney L Pereira; Peter H Seeberger
Journal: Proc Natl Acad Sci U S A Date: 2018-12-07 Impact factor: 11.205

3. A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

Authors: Sharavathi Guddehalli Parameswarappa; Katrin Reppe; Andreas Geissner; Petra Ménová; Subramanian Govindan; Adam D J Calow; Annette Wahlbrink; Markus W Weishaupt; Bopanna Ponnappa Monnanda; Roland Lawrence Bell; Liise-Anne Pirofski; Norbert Suttorp; Leif Erik Sander; Martin Witzenrath; Claney Lebev Pereira; Chakkumkal Anish; Peter H Seeberger
Journal: Cell Chem Biol Date: 2016-11-03 Impact factor: 8.116

4. Microbe-focused glycan array screening platform.

Authors: Andreas Geissner; Anika Reinhardt; Christoph Rademacher; Timo Johannssen; João Monteiro; Bernd Lepenies; Michel Thépaut; Franck Fieschi; Jana Mrázková; Michaela Wimmerova; Frank Schuhmacher; Sebastian Götze; Dan Grünstein; Xiaoqiang Guo; Heung Sik Hahm; Jeyakumar Kandasamy; Daniele Leonori; Christopher E Martin; Sharavathi G Parameswarappa; Sandip Pasari; Mark K Schlegel; Hidenori Tanaka; Guozhi Xiao; You Yang; Claney L Pereira; Chakkumkal Anish; Peter H Seeberger
Journal: Proc Natl Acad Sci U S A Date: 2019-01-22 Impact factor: 11.205

5. Examining galectin binding specificity using glycan microarrays.

Authors: Connie M Arthur; Lílian Cataldi Rodrigues; Marcelo Dias Baruffi; Harold C Sullivan; Jamie Heimburg-Molinaro; Dave F Smith; Richard D Cummings; Sean R Stowell
Journal: Methods Mol Biol Date: 2015

6. A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

Authors: Benjamin Schumann; Heung Sik Hahm; Sharavathi G Parameswarappa; Katrin Reppe; Annette Wahlbrink; Subramanian Govindan; Paulina Kaplonek; Liise-Anne Pirofski; Martin Witzenrath; Chakkumkal Anish; Claney L Pereira; Peter H Seeberger
Journal: Sci Transl Med Date: 2017-03-08 Impact factor: 17.956

Glycan arrays as tools for infectious disease research.

1. Combining 3D structure with glycan array data provides insight into the origin of glycan specificity.

2. Improving vaccines against Streptococcus pneumoniae using synthetic glycans.

3. A Semi-synthetic Oligosaccharide Conjugate Vaccine Candidate Confers Protection against Streptococcus pneumoniae Serotype 3 Infection.

4. Microbe-focused glycan array screening platform.

5. Examining galectin binding specificity using glycan microarrays.

6. A semisynthetic Streptococcus pneumoniae serotype 8 glycoconjugate vaccine.

7. Whole-Cell Cancer Vaccines Induce Large Antibody Responses to Carbohydrates and Glycoproteins.

8. Structural Hot Spots Determine Functional Diversity of the Candida glabrata Epithelial Adhesin Family.

9. The Glycan Array Platform as a Tool to Identify Carbohydrate Antigens.

Review 10. Recent advances in employing molecular modelling to determine the specificity of glycan-binding proteins.