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Literature DB >> 24533588

Lipidomic "deep profiling": an enhanced workflow to reveal new molecular species of signaling lipids.

Pradeep Narayanaswamy¹, Sudhirkumar Shinde, Robert Sulc, Rachel Kraut, Gregory Staples, Chung Hwee Thiam, Rudolf Grimm, Börje Sellergren, Federico Torta, Markus R Wenk.

Abstract

Current mass spectrometry-based lipidomics aims to comprehensively cover wide ranges of lipid classes. We introduce a strategy to capture phospho-monoester lipids and improve the detection of long-chain base phosphates (LCB-Ps, e.g., sphingosine-1-phosphate). Ten novel LCB-Ps (d18:2, t20:1, odd carbon forms) were discovered and characterized in tissues from human and mouse, as well in D. melanogaster and S. cerevisiae. These findings have immediate relevance for our understanding of sphingosine-1-phosphate biosynthesis, signaling, and degradation.

Entities: Chemical Species

Mesh：

Substances：
Lipids

Year: 2014 PMID： 24533588 DOI： 10.1021/ac4039652

Source DB: PubMed Journal: Anal Chem ISSN： 0003-2700 Impact factor: 6.986

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Cited

24 in total

Review 1. Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs.

Authors: Mitchell K P Lai; Wee Siong Chew; Federico Torta; Angad Rao; Greg L Harris; Jerold Chun; Deron R Herr
Journal: Neuromolecular Med Date: 2016-07-08 Impact factor: 3.843

2. Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence.

Authors: Wee Siong Chew; Federico Torta; Shanshan Ji; Hyungwon Choi; Husna Begum; Xueling Sim; Chin Meng Khoo; Eric Yin Hao Khoo; Wei-Yi Ong; Rob M Van Dam; Markus R Wenk; E Shyong Tai; Deron R Herr
Journal: JCI Insight Date: 2019-06-04

3. Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.

Authors: Thiet M Vu; Ayako-Nakamura Ishizu; Juat Chin Foo; Xiu Ru Toh; Fangyu Zhang; Ding Ming Whee; Federico Torta; Amaury Cazenave-Gassiot; Takayoshi Matsumura; Sangho Kim; Sue-Anne E S Toh; Toshio Suda; David L Silver; Markus R Wenk; Long N Nguyen
Journal: Nature Date: 2017-10-18 Impact factor: 49.962

4. 1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.

Authors: Ting Wang; Zheng Wang; Lauriane de Fabritus; Jinglian Tao; Essa M Saied; Ho-Joon Lee; Bulat R Ramazanov; Benjamin Jackson; Daniel Burkhardt; Mikhail Parker; Anne S Gleinich; Zhirui Wang; Dong Eun Seo; Ting Zhou; Shihao Xu; Irina Alecu; Parastoo Azadi; Christoph Arenz; Thorsten Hornemann; Smita Krishnaswamy; Serge A van de Pavert; Susan M Kaech; Natalia B Ivanova; Fabio R Santori
Journal: Dev Cell Date: 2021-11-10 Impact factor: 12.270

5. Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy.

Authors: Wei Wang; Ping Xiang; Wee Siong Chew; Federico Torta; Aishwarya Bandla; Violeta Lopez; Wei Lun Seow; Brenda Wan Shing Lam; Jing Kai Chang; Peiyan Wong; Kanokporn Chayaburakul; Wei-Yi Ong; Markus R Wenk; Raghav Sundar; Deron R Herr
Journal: J Biol Chem Date: 2019-12-27 Impact factor: 5.157

6. Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation.

Authors: Piming Zhao; Isaac D Liu; Jeffrey B Hodgin; Peter I Benke; Jeremy Selva; Federico Torta; Markus R Wenk; James A Endrizzi; Olivia West; Weixing Ou; Emily Tang; Denise Li-Meng Goh; Stacey Kiat-Hong Tay; Hui-Kim Yap; Alwin Loh; Nicole Weaver; Bonnie Sullivan; Austin Larson; Megan A Cooper; Khalid Alhasan; Abdullah A Alangari; Suha Salim; Evren Gumus; Karin Chen; Martin Zenker; Friedhelm Hildebrandt; Julie D Saba
Journal: J Inherit Metab Dis Date: 2020-05-04 Impact factor: 4.982

Lipidomic "deep profiling": an enhanced workflow to reveal new molecular species of signaling lipids.

Review 1. Biological Effects of Naturally Occurring Sphingolipids, Uncommon Variants, and Their Analogs.

2. Large-scale lipidomics identifies associations between plasma sphingolipids and T2DM incidence.

3. Mfsd2b is essential for the sphingosine-1-phosphate export in erythrocytes and platelets.

4. 1-deoxysphingolipids bind to COUP-TF to modulate lymphatic and cardiac cell development.

5. Activation of sphingosine 1-phosphate receptor 2 attenuates chemotherapy-induced neuropathy.

6. Responsiveness of sphingosine phosphate lyase insufficiency syndrome to vitamin B6 cofactor supplementation.

Review 7. Lipidomics: Prospects from a technological perspective.

8. A new model for regulation of sphingosine kinase 1 translocation to the plasma membrane in breast cancer cells.

9. Endogenous agonist-bound S1PR3 structure reveals determinants of G protein-subtype bias.

Review 10. Sphingosine 1-phosphate and its regulatory role in vascular endothelial cells.