Literature DB >> 24532929

Clinical evaluation of Deep Anterior Lamellar Keratoplasty (DALK) for stromal corneal opacities.

Vijay Mathur1, J K S Parihar2, V K Srivastava3, A Avasthi4.   

Abstract

BACKGROUND: Corneal scars are commonly formed following many diseases of the eye like trauma, inflammation and infections. They lead to permanent diminution of vision which can be managed by Penetrating Keratoplasty (PK). PK is removing diseased as well as healthy tissues and is associated with many post-operative complications. Deep Anterior Lamellar Keratoplasty (DALK) is a relatively newer procedure which replaces only the diseased stroma, leaving the original corneal endothelium intact. This procedure is associated with lesser incidence of post-operative complications.
METHODS: The study was conducted at a large tertiary care centre. 10 patients with stromal corneal scars were subjected to DALK and results were analysed after 06 months. Poor quality donor corneal tissue of B- and C grade was used in all cases.
RESULTS: 7 out of 10 patients (70%) undergoing DALK had post-operative visual acuity of 6/24 or better. 03 patients who did not have adequate recovery of visual acuity were due to over-riding of the graft in 01 case (10%), fungal keratitis in 01 case (10%) and interface haze in 01 case (10%).
CONCLUSION: DALK is a promising new technique for management of superficial corneal stromal scars using poor quality donor corneal tissue. Initial results are encouraging with minimal complications.

Entities:  

Keywords:  Descemet's perforation; Graft rejection; Interface haze; Lamellar keratoplasty; Superficial stromal corneal scars

Year:  2012        PMID: 24532929      PMCID: PMC3862359          DOI: 10.1016/j.mjafi.2012.04.023

Source DB:  PubMed          Journal:  Med J Armed Forces India        ISSN: 0377-1237


  13 in total

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2.  Deep lamellar keratoplasty by intracorneal dissection: a prospective clinical and confocal microscopic study.

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4.  Deep lamellar keratoplasty with complete removal of pathological stroma for vision improvement.

Authors:  J Sugita; J Kondo
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5.  A new surgical technique for deep stromal, anterior lamellar keratoplasty.

Authors:  G R Melles; F Lander; F J Rietveld; L Remeijer; W H Beekhuis; P S Binder
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Review 6.  Deep anterior lamellar keratoplasty.

Authors:  Shigeto Shimmura; Kazuo Tsubota
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7.  Big-bubble technique to bare Descemet's membrane in anterior lamellar keratoplasty.

Authors:  Mohammed Anwar; Klaus D Teichmann
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8.  Long-term graft survival after penetrating keratoplasty.

Authors:  Robert W Thompson; Marianne O Price; Patrick J Bowers; Francis W Price
Journal:  Ophthalmology       Date:  2003-07       Impact factor: 12.079

9.  Use of a "small-bubble technique" to increase the success of Anwar's "big-bubble technique" for deep lamellar keratoplasty with complete baring of Descemet's membrane.

Authors:  Anand Parthasarathy; Yong Ming Por; Donald T H Tan
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10.  Five-year corneal graft survival. A large, single-center patient cohort.

Authors:  F W Price; W E Whitson; K S Collins; R G Marks
Journal:  Arch Ophthalmol       Date:  1993-06
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3.  Traumatic Wound Dehiscence after Keratoplasty: Characteristics, Risk Factors, and Visual Outcome.

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4.  Clinical evaluation of deep anterior lamellar keratoplasty using glycerol-cryopreserved corneal tissues for refractory herpetic stromal keratitis: An observational study.

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5.  Demographic and clinical profile, surgical outcome, and quality of life in patients who underwent bilateral lamellar corneal grafts.

Authors:  Sreelakshmi P Amar; Rajesh Sinha; Nidhi Kalra; Tushar Agarwal; Namrata Sharma; Jeewan S Titiyal
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