| Literature DB >> 24531200 |
Nikhilesh Arya1, Archana Y Jagdale2, Tushar A Patil2, Shradha S Yeramwar2, Sidharam S Holikatti2, Jaya Dwivedi3, Chamanlal J Shishoo4, Kishor S Jain5.
Abstract
Azetidin-2-ones, commonly referred as β-lactams, represent a unique ring system, with interesting chemistry and great biological potential. Besides its well known antibiotic activity, this ring system exhibits a wide range of activities, attracting the attention of researchers. The biological and pharmacological profile of azetidin-2-ones is reviewed here comprehensively with several examples under fourteen different activity heads. The chemistry and methods of synthesis have also been discussed.Entities:
Keywords: Azetidin-2-ones; Pharmacological profile; Synthesis; β-Lactam
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Year: 2014 PMID： 24531200 DOI： 10.1016/j.ejmech.2014.01.002
Source DB: PubMed Journal: Eur J Med Chem ISSN： 0223-5234 Impact factor: 6.514