Literature DB >> 24528242

The Concise Guide to PHARMACOLOGY 2013/14: transporters.

Stephen P H Alexander1, Helen E Benson, Elena Faccenda, Adam J Pawson, Joanna L Sharman, Michael Spedding, John A Peters, Anthony J Harmar.   

Abstract

The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.12444/full. Transporters are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, catalytic receptors, nuclear hormone receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates.
Copyright © 2013 The British Pharmacological Society.

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Year:  2013        PMID: 24528242      PMCID: PMC3892292          DOI: 10.1111/bph.12450

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN: 0007-1188            Impact factor:   8.739


  667 in total

Review 1.  A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps.

Authors:  J Preben Morth; Bjørn P Pedersen; Morten J Buch-Pedersen; Jens Peter Andersen; Bente Vilsen; Michael G Palmgren; Poul Nissen
Journal:  Nat Rev Mol Cell Biol       Date:  2011-01       Impact factor: 94.444

Review 2.  Hijacking solute carriers for proton-coupled drug transport.

Authors:  Catriona M H Anderson; David T Thwaites
Journal:  Physiology (Bethesda)       Date:  2010-12

3.  A novel member of solute carrier family 25 (SLC25A42) is a transporter of coenzyme A and adenosine 3',5'-diphosphate in human mitochondria.

Authors:  Giuseppe Fiermonte; Eleonora Paradies; Simona Todisco; Carlo M T Marobbio; Ferdinando Palmieri
Journal:  J Biol Chem       Date:  2009-05-08       Impact factor: 5.157

4.  Discovery of the first selective inhibitor of excitatory amino acid transporter subtype 1.

Authors:  Anders A Jensen; Mette N Erichsen; Christina W Nielsen; Tine B Stensbøl; Jan Kehler; Lennart Bunch
Journal:  J Med Chem       Date:  2009-02-26       Impact factor: 7.446

5.  Glutamate transporter coupling to Na,K-ATPase.

Authors:  Erin M Rose; Joseph C P Koo; Jordan E Antflick; Syed M Ahmed; Stephane Angers; David R Hampson
Journal:  J Neurosci       Date:  2009-06-24       Impact factor: 6.167

6.  Glucose transport by human renal Na+/D-glucose cotransporters SGLT1 and SGLT2.

Authors:  Charles S Hummel; Chuan Lu; Donald D F Loo; Bruce A Hirayama; Andrew A Voss; Ernest M Wright
Journal:  Am J Physiol Cell Physiol       Date:  2010-10-27       Impact factor: 4.249

7.  Surprising substrate versatility in SLC5A6: Na+-coupled I- transport by the human Na+/multivitamin transporter (hSMVT).

Authors:  Fernanda Delmondes de Carvalho; Matthias Quick
Journal:  J Biol Chem       Date:  2010-10-27       Impact factor: 5.157

Review 8.  Transport of lipids by ABC proteins: interactions and implications for cellular toxicity, viability and function.

Authors:  Irving L M H Aye; Ambika T Singh; Jeffrey A Keelan
Journal:  Chem Biol Interact       Date:  2009-05-06       Impact factor: 5.192

9.  The glycine transport inhibitor sarcosine is an NMDA receptor co-agonist that differs from glycine.

Authors:  Hai Xia Zhang; Krzysztof Hyrc; Liu Lin Thio
Journal:  J Physiol       Date:  2009-05-11       Impact factor: 5.182

10.  SLC30A3 (ZnT3) oligomerization by dityrosine bonds regulates its subcellular localization and metal transport capacity.

Authors:  Gloria Salazar; Juan M Falcon-Perez; Robert Harrison; Victor Faundez
Journal:  PLoS One       Date:  2009-06-12       Impact factor: 3.240

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  108 in total

1.  Inhibition of L-carnitine biosynthesis and transport by methyl-γ-butyrobetaine decreases fatty acid oxidation and protects against myocardial infarction.

Authors:  E Liepinsh; M Makrecka-Kuka; J Kuka; R Vilskersts; E Makarova; H Cirule; E Loza; D Lola; S Grinberga; O Pugovics; I Kalvins; M Dambrova
Journal:  Br J Pharmacol       Date:  2015-01-12       Impact factor: 8.739

2.  Clinically used selective oestrogen receptor modulators increase LDL receptor activity in primary human lymphocytes.

Authors:  F Cerrato; M E Fernández-Suárez; R Alonso; M Alonso; C Vázquez; O Pastor; P Mata; M A Lasunción; D Gómez-Coronado
Journal:  Br J Pharmacol       Date:  2015-01-08       Impact factor: 8.739

Review 3.  TRP channels in the skin.

Authors:  Balázs I Tóth; Attila Oláh; Attila Gábor Szöllősi; Tamás Bíró
Journal:  Br J Pharmacol       Date:  2014-05       Impact factor: 8.739

4.  Pharmacological identification of a guanidine-containing β-alanine analogue with low micromolar potency and selectivity for the betaine/GABA transporter 1 (BGT1).

Authors:  Anas Al-Khawaja; Jette G Petersen; Maria Damgaard; Mette H Jensen; Stine B Vogensen; Maria E K Lie; Bolette Kragholm; Hans Bräuner-Osborne; Rasmus P Clausen; Bente Frølund; Petrine Wellendorph
Journal:  Neurochem Res       Date:  2014-05-23       Impact factor: 3.996

5.  A polyspecific drug/proton antiporter mediates diphenhydramine and clonidine transport at the mouse blood-retinal barrier.

Authors:  Hélène Chapy; Pascal André; Xavier Declèves; Jean-Michel Scherrmann; Salvatore Cisternino
Journal:  Br J Pharmacol       Date:  2015-08-10       Impact factor: 8.739

Review 6.  Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.

Authors:  M Borsotto; J Veyssiere; H Moha Ou Maati; C Devader; J Mazella; C Heurteaux
Journal:  Br J Pharmacol       Date:  2014-11-24       Impact factor: 8.739

Review 7.  Developmental rodent models of fear and anxiety: from neurobiology to pharmacology.

Authors:  Despina E Ganella; Jee Hyun Kim
Journal:  Br J Pharmacol       Date:  2014-07-01       Impact factor: 8.739

8.  3-Iodothyroacetic acid lacks thermoregulatory and cardiovascular effects in vivo.

Authors:  Carolin S Hoefig; Simon F Jacobi; Amy Warner; Lisbeth Harder; Nancy Schanze; Björn Vennström; Jens Mittag
Journal:  Br J Pharmacol       Date:  2015-06-09       Impact factor: 8.739

9.  Pharmacological profile of novel psychoactive benzofurans.

Authors:  Anna Rickli; Simone Kopf; Marius C Hoener; Matthias E Liechti
Journal:  Br J Pharmacol       Date:  2015-04-24       Impact factor: 8.739

10.  Regulatory role of the cannabinoid CB2 receptor in stress-induced neuroinflammation in mice.

Authors:  S Zoppi; J L Madrigal; J R Caso; M S García-Gutiérrez; J Manzanares; J C Leza; B García-Bueno
Journal:  Br J Pharmacol       Date:  2014-06       Impact factor: 8.739

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