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Literature DB >> 24524352

Tortuosenes A and B, new diterpenoid metabolites from the Formosan soft coral Sarcophyton tortuosum.

Kuan-Hua Lin¹, Yen-Ju Tseng, Bo-Wei Chen, Tsong-Long Hwang, Hsing-Yin Chen, Chang-Feng Dai, Jyh-Horng Sheu.

Abstract

Tortuosenes A and B (1 and 2), possessing new diterpenoid molecular structures, were isolated from the Formosan soft coral Sarcophyton tortuosum along with a known cembrane, emblide (3). The structures of 1 and 2 were established by extensive spectroscopic analysis, and the absolute configuration of 1 was determined by TDDFT ECD calculations. Tortuosene A was found to display significant inhibitory effects on the generation of the superoxide anion in N-formyl-methionyl-leucyl-phenylalanine/cytochalasin B (fMLP/CB)-induced neutrophils.

Entities: Chemical Species

Mesh：

Substances：

Year: 2014 PMID： 24524352 DOI： 10.1021/ol403723b

Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005

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Cited

10 in total

1. Computationally Assisted Structural Elucidation of Cembranoids from the Soft Coral Sarcophyton tortuosum.

Authors: Chih-Hua Chao; Kuan-Hua Lin; Chiung-Yao Huang; Tsong-Long Hwang; Chang-Feng Dai; Hui-Chi Huang; Jyh-Horng Sheu
Journal: Mar Drugs Date: 2022-04-27 Impact factor: 6.085

Review 2. Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.

Authors: Igor A Schepetkin; Andrei I Khlebnikov; Liliya N Kirpotina; Mark T Quinn
Journal: Int Immunopharmacol Date: 2015-09-15 Impact factor: 4.932

Review 3. Marine Natural Product Inhibitors of Neutrophil-Associated Inflammation.

Authors: Chun-Yu Chen; Yung-Fong Tsai; Wen-Yi Chang; Shun-Chin Yang; Tsong-Long Hwang
Journal: Mar Drugs Date: 2016-07-26 Impact factor: 5.118

Review 4. Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Authors: Alejandro M S Mayer; Aimee J Guerrero; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Fumiaki Nakamura; Nobuhiro Fusetani
Journal: Mar Drugs Date: 2019-12-19 Impact factor: 5.118

Review 5. Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review.

Authors: Yasmin A Elkhawas; Ahmed M Elissawy; Mohamed S Elnaggar; Nada M Mostafa; Eman M Kamal; Mokhtar M Bishr; Abdel Nasser B Singab; Osama M Salama
Journal: Mar Drugs Date: 2020-01-06 Impact factor: 5.118

Tortuosenes A and B, new diterpenoid metabolites from the Formosan soft coral Sarcophyton tortuosum.

1. Computationally Assisted Structural Elucidation of Cembranoids from the Soft Coral Sarcophyton tortuosum.

Review 2. Antagonism of human formyl peptide receptor 1 with natural compounds and their synthetic derivatives.

Review 3. Marine Natural Product Inhibitors of Neutrophil-Associated Inflammation.

Review 4. Marine Pharmacology in 2014-2015: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, Antiviral, and Anthelmintic Activities; Affecting the Immune and Nervous Systems, and Other Miscellaneous Mechanisms of Action.

Review 5. Chemical Diversity in Species Belonging to Soft Coral Genus Sacrophyton and Its Impact on Biological Activity: A Review.

6. Anti-Inflammatory Cembranoids from a Formosa Soft Coral Sarcophyton cherbonnieri.

7. Cherbonolides M and N from a Formosan Soft Coral Sarcophyton cherbonnieri.

8. Glaucumolides A and B, Biscembranoids with New Structural Type from a Cultured Soft Coral Sarcophyton glaucum.

9. New Cembranoids and a Biscembranoid Peroxide from the Soft Coral Sarcophyton cherbonnieri.

10. Isolation and Structure Elucidation of Cembranoids from a Dongsha Atoll Soft Coral Sarcophyton stellatum.