Literature DB >> 24523987

From concept representations to ontologies: a paradigm shift in health informatics?

Stefan Schulz1, Laszlo Balkanyi2, Ronald Cornet3, Olivier Bodenreider4.   

Abstract

OBJECTIVES: This work aims at uncovering challenges in biomedical knowledge representation research by providing an understanding of what was historically called "medical concept representation" and used as the name for a working group of the International Medical Informatics Association.
METHODS: Bibliometrics, text mining, and a social media survey compare the research done in this area between two periods, before and after 2000.
RESULTS: Both the opinion of socially active groups of researchers and the interpretation of bibliometric data since 1988 suggest that the focus of research has moved from "medical concept representation" to "medical ontologies".
CONCLUSIONS: It remains debatable whether the observed change amounts to a paradigm shift or whether it simply reflects changes in naming, following the natural evolution of ontology research and engineering activities in the 1990s. The availability of powerful tools to handle ontologies devoted to certain areas of biomedicine has not resulted in a large-scale breakthrough beyond advances in basic research.

Entities:  

Keywords:  Data Mining; Publishing; Semantics; Terminology; Vocabulary

Year:  2013        PMID: 24523987      PMCID: PMC3920035          DOI: 10.4258/hir.2013.19.4.235

Source DB:  PubMed          Journal:  Healthc Inform Res        ISSN: 2093-3681


  19 in total

1.  Clinical terminology: why is it so hard?

Authors:  A L Rector
Journal:  Methods Inf Med       Date:  1999-12       Impact factor: 2.176

2.  SNOMED clinical terms: overview of the development process and project status.

Authors:  M Q Stearns; C Price; K A Spackman; A Y Wang
Journal:  Proc AMIA Symp       Date:  2001

3.  The Unified Medical Language System (UMLS): integrating biomedical terminology.

Authors:  Olivier Bodenreider
Journal:  Nucleic Acids Res       Date:  2004-01-01       Impact factor: 16.971

Review 4.  Methods in biomedical ontology.

Authors:  Alexander C Yu
Journal:  J Biomed Inform       Date:  2005-12-07       Impact factor: 6.317

5.  The OBO Foundry: coordinated evolution of ontologies to support biomedical data integration.

Authors:  Barry Smith; Michael Ashburner; Cornelius Rosse; Jonathan Bard; William Bug; Werner Ceusters; Louis J Goldberg; Karen Eilbeck; Amelia Ireland; Christopher J Mungall; Neocles Leontis; Philippe Rocca-Serra; Alan Ruttenberg; Susanna-Assunta Sansone; Richard H Scheuermann; Nigam Shah; Patricia L Whetzel; Suzanna Lewis
Journal:  Nat Biotechnol       Date:  2007-11       Impact factor: 54.908

6.  Mapping the domain of medical informatics.

Authors:  M J Schuemie; J L Talmon; P W Moorman; J A Kors
Journal:  Methods Inf Med       Date:  2009       Impact factor: 2.176

7.  Concept Systems and Ontologies: Recommendations for Basic Terminology.

Authors:  Gunnar O Klein; Barry Smith
Journal:  Trans Jpn Soc Artif Intell       Date:  2010-01-01

8.  Medical-concept models and medical records: an approach based on GALEN and PEN&PAD.

Authors:  A L Rector; A J Glowinski; W A Nowlan; A Rossi-Mori
Journal:  J Am Med Inform Assoc       Date:  1995 Jan-Feb       Impact factor: 4.497

9.  Modeling biomedical experimental processes with OBI.

Authors:  Ryan R Brinkman; Mélanie Courtot; Dirk Derom; Jennifer M Fostel; Yongqun He; Phillip Lord; James Malone; Helen Parkinson; Bjoern Peters; Philippe Rocca-Serra; Alan Ruttenberg; Susanna-Assunta Sansone; Larisa N Soldatova; Christian J Stoeckert; Jessica A Turner; Jie Zheng
Journal:  J Biomed Semantics       Date:  2010-06-22

10.  Relations in biomedical ontologies.

Authors:  Barry Smith; Werner Ceusters; Bert Klagges; Jacob Köhler; Anand Kumar; Jane Lomax; Chris Mungall; Fabian Neuhaus; Alan L Rector; Cornelius Rosse
Journal:  Genome Biol       Date:  2005-04-28       Impact factor: 13.583

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  10 in total

1.  Ontology-based Vaccine and Drug Adverse Event Representation and Theory-guided Systematic Causal Network Analysis toward Integrative Pharmacovigilance Research.

Authors:  Yongqun He
Journal:  Curr Pharmacol Rep       Date:  2016-03-11

2.  Precision omics data integration and analysis with interoperable ontologies and their application for COVID-19 research.

Authors:  Zhigang Wang; Yongqun He
Journal:  Brief Funct Genomics       Date:  2021-07-17       Impact factor: 4.840

3.  Describing the breakbone fever: IDODEN, an ontology for dengue fever.

Authors:  Elvira Mitraka; Pantelis Topalis; Vicky Dritsou; Emmanuel Dialynas; Christos Louis
Journal:  PLoS Negl Trop Dis       Date:  2015-02-03

Review 4.  The eXtensible ontology development (XOD) principles and tool implementation to support ontology interoperability.

Authors:  Yongqun He; Zuoshuang Xiang; Jie Zheng; Yu Lin; James A Overton; Edison Ong
Journal:  J Biomed Semantics       Date:  2018-01-12

5.  Ontology-based systematic representation and analysis of traditional Chinese drugs against rheumatism.

Authors:  Qingping Liu; Jiahao Wang; Yan Zhu; Yongqun He
Journal:  BMC Syst Biol       Date:  2017-12-21

6.  ODAE: Ontology-based systematic representation and analysis of drug adverse events and its usage in study of adverse events given different patient age and disease conditions.

Authors:  Hong Yu; Solomiya Nysak; Noemi Garg; Edison Ong; Xianwei Ye; Xiangyan Zhang; Yongqun He
Journal:  BMC Bioinformatics       Date:  2019-05-01       Impact factor: 3.169

7.  Ontological modeling and analysis of experimentally or clinically verified drugs against coronavirus infection.

Authors:  Yingtong Liu; Junguk Hur; Wallace K B Chan; Zhigang Wang; Jiangan Xie; Duxin Sun; Samuel Handelman; Jonathan Sexton; Hong Yu; Yongqun He
Journal:  Sci Data       Date:  2021-01-13       Impact factor: 6.444

8.  Ontology-Based Classification and Analysis of Adverse Events Associated With the Usage of Chloroquine and Hydroxychloroquine.

Authors:  Jamie Ngai; Madison Kalter; James Brian Byrd; Rebecca Racz; Yongqun He
Journal:  Front Pharmacol       Date:  2022-03-23       Impact factor: 5.810

9.  The Ontology of Biological and Clinical Statistics (OBCS)-based statistical method standardization and meta-analysis of host responses to yellow fever vaccines.

Authors:  Jie Zheng; Huan Li; Qingzhi Liu; Yongqun He
Journal:  Quant Biol       Date:  2017-11-12

10.  The Ontology of Biological and Clinical Statistics (OBCS) for standardized and reproducible statistical analysis.

Authors:  Jie Zheng; Marcelline R Harris; Anna Maria Masci; Yu Lin; Alfred Hero; Barry Smith; Yongqun He
Journal:  J Biomed Semantics       Date:  2016-09-14
  10 in total

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