Literature DB >> 24519100

Accuracy of ovarian and colon cancer risk assessments by U.S. physicians.

Laura-Mae Baldwin1, Katrina F Trivers, C Holly A Andrilla, Barbara Matthews, Jacqueline W Miller, Denise M Lishner, Barbara A Goff.   

Abstract

BACKGROUND: Studies have shown a mismatch between published cancer screening and genetic counseling referral recommendations and physician-reported screening and referral practices. Inaccurate cancer risk assessment is one potential cause of this mismatch.
OBJECTIVE: To assess U.S. physicians' ability to accurately determine a woman's colon and ovarian cancer risk level. DESIGN, PARTICIPANTS: Cross-sectional survey of U.S. family physicians, general internists, and obstetrician-gynecologists. A twelve-page questionnaire with a vignette of a woman's annual examination included a question about the patient's level of colon and ovarian cancer risk. The final study sample included 1,555 physicians weighted to represent practicing U.S. physicians nationally. MAIN MEASURE: Accuracy of physicians' ovarian and colon cancer risk assessments. KEY
RESULTS: Overall, most physicians accurately assessed women's risk of ovarian (57.0%, CI 54.3, 59.6) and colon cancer (62.0%, CI 59.4, 64.6). However, 27.1% (CI 23.0, 31.6) of physicians overestimated the ovarian cancer risk among women at the same risk as the general population, and 65.1% (CI 60.2, 69.7) underestimated ovarian cancer risk among women at much higher risk than the general population. Physicians overestimated colon more than ovarian cancer risk (38.0%, CI 35.4, 40.6 vs. 27.1%, CI 23.0, 31.6) for women at the same risk as the general population.
CONCLUSIONS: Physicians' misestimation of patient ovarian and colon cancer risk may put average risk patients in jeopardy of unnecessary screening and higher risk patients in jeopardy of missed opportunities for prevention or early detection of cancers.

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Year:  2014        PMID: 24519100      PMCID: PMC4000350          DOI: 10.1007/s11606-014-2768-2

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


  57 in total

1.  Vignette-based study of ovarian cancer screening: do U.S. physicians report adhering to evidence-based recommendations?

Authors:  Laura-Mae Baldwin; Katrina F Trivers; Barbara Matthews; C Holly A Andrilla; Jacqueline W Miller; Donna L Berry; Denise M Lishner; Barbara A Goff
Journal:  Ann Intern Med       Date:  2012-02-07       Impact factor: 25.391

Review 2.  A decade of public health genomics in the United States: centers for disease control and prevention 1997-2007.

Authors:  M J Khoury; S Bowen; L A Bradley; R Coates; N F Dowling; M Gwinn; K Kolor; C A Moore; J St Pierre; R Valdez; P W Yoon
Journal:  Public Health Genomics       Date:  2008-09-03       Impact factor: 2.000

3.  Estimating model-adjusted risks, risk differences, and risk ratios from complex survey data.

Authors:  Gayle S Bieler; G Gordon Brown; Rick L Williams; Donna J Brogan
Journal:  Am J Epidemiol       Date:  2010-02-04       Impact factor: 4.897

4.  Screening for ovarian cancer: U.S. Preventive Services Task Force reaffirmation recommendation statement.

Authors:  Virginia A Moyer
Journal:  Ann Intern Med       Date:  2012-12-18       Impact factor: 25.391

5.  Familial risk of cancer and knowledge and use of genetic testing.

Authors:  Heather J Baer; Phyllis Brawarsky; Michael F Murray; Jennifer S Haas
Journal:  J Gen Intern Med       Date:  2010-04-02       Impact factor: 5.128

6.  Receipt of genetic counseling recommendations among black women at high risk for BRCA mutations.

Authors:  Hayley S Thompson; Katarina Sussner; Marc D Schwartz; Tiffany Edwards; Andrea Forman; Lina Jandorf; Karen Brown; Dana H Bovbjerg; Heiddis B Valdimarsdottir
Journal:  Genet Test Mol Biomarkers       Date:  2012-10-11

7.  Association of risk-reducing surgery in BRCA1 or BRCA2 mutation carriers with cancer risk and mortality.

Authors:  Susan M Domchek; Tara M Friebel; Christian F Singer; D Gareth Evans; Henry T Lynch; Claudine Isaacs; Judy E Garber; Susan L Neuhausen; Ellen Matloff; Rosalind Eeles; Gabriella Pichert; Laura Van t'veer; Nadine Tung; Jeffrey N Weitzel; Fergus J Couch; Wendy S Rubinstein; Patricia A Ganz; Mary B Daly; Olufunmilayo I Olopade; Gail Tomlinson; Joellen Schildkraut; Joanne L Blum; Timothy R Rebbeck
Journal:  JAMA       Date:  2010-09-01       Impact factor: 56.272

8.  Reported referral for genetic counseling or BRCA 1/2 testing among United States physicians: a vignette-based study.

Authors:  Katrina F Trivers; Laura-Mae Baldwin; Jacqueline W Miller; Barbara Matthews; C Holly A Andrilla; Denise M Lishner; Barbara A Goff
Journal:  Cancer       Date:  2011-07-25       Impact factor: 6.860

9.  Awareness and utilization of BRCA1/2 testing among U.S. primary care physicians.

Authors:  Cecelia A Bellcross; Katherine Kolor; Katrina A B Goddard; Ralph J Coates; Michele Reyes; Muin J Khoury
Journal:  Am J Prev Med       Date:  2011-01       Impact factor: 5.043

10.  Effect of screening on ovarian cancer mortality: the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Randomized Controlled Trial.

Authors:  Saundra S Buys; Edward Partridge; Amanda Black; Christine C Johnson; Lois Lamerato; Claudine Isaacs; Douglas J Reding; Robert T Greenlee; Lance A Yokochi; Bruce Kessel; E David Crawford; Timothy R Church; Gerald L Andriole; Joel L Weissfeld; Mona N Fouad; David Chia; Barbara O'Brien; Lawrence R Ragard; Jonathan D Clapp; Joshua M Rathmell; Thomas L Riley; Patricia Hartge; Paul F Pinsky; Claire S Zhu; Grant Izmirlian; Barnett S Kramer; Anthony B Miller; Jian-Lun Xu; Philip C Prorok; John K Gohagan; Christine D Berg
Journal:  JAMA       Date:  2011-06-08       Impact factor: 157.335

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  3 in total

1.  Physicians' Awareness and Utilization of Genetic Services in Texas.

Authors:  Callie Diamonstein; Blair Stevens; S Shahrukh Hashmi; Jerrie Refuerzo; Cathy Sullivan; Jennifer Hoskovec
Journal:  J Genet Couns       Date:  2017-12-26       Impact factor: 2.537

2.  Clinical utility of a Web-enabled risk-assessment and clinical decision support program.

Authors:  Lori A Orlando; R Ryanne Wu; Rachel A Myers; Adam H Buchanan; Vincent C Henrich; Elizabeth R Hauser; Geoffrey S Ginsburg
Journal:  Genet Med       Date:  2016-03-03       Impact factor: 8.822

3.  Referral to cancer genetic counseling: do migrant status and patients' educational background matter?

Authors:  J A M van der Giessen; E van Riel; M E Velthuizen; A M van Dulmen; M G E M Ausems
Journal:  J Community Genet       Date:  2017-09-04
  3 in total

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