Literature DB >> 24510341

Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia.

Jean Grisouard1, Hui Hao-Shen, Stephan Dirnhofer, Kay-Uwe Wagner, Radek C Skoda.   

Abstract

Entities:  

Keywords:  Jak2; adult hematopoiesis

Mesh：

Substances：

Year:  2014        PMID： 24510341      PMCID： PMC3971094          DOI： 10.3324/haematol.2013.100016

Source DB:  PubMed          Journal:  Haematologica        ISSN： 0390-6078            Impact factor:   9.941


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  15 in total

1.  Jak1 plays an essential role for receptor phosphorylation and Stat activation in response to granulocyte colony-stimulating factor.

Authors:  K Shimoda; J Feng; H Murakami; S Nagata; D Watling; N C Rogers; G R Stark; I M Kerr; J N Ihle
Journal:  Blood       Date:  1997-07-15       Impact factor: 22.113

2.  Jak2 deficiency defines an essential developmental checkpoint in definitive hematopoiesis.

Authors:  H Neubauer; A Cumano; M Müller; H Wu; U Huffstadt; K Pfeffer
Journal:  Cell       Date:  1998-05-01       Impact factor: 41.582

3.  Interferon-gamma enhances megakaryocyte colony-stimulating activity in murine bone marrow cells.

Authors:  K Tsuji-Takayama; H Tahata; A Harashima; Y Nishida; N Izumi; S Fukuda; T Ohta; M Kurimoto
Journal:  J Interferon Cytokine Res       Date:  1996-09       Impact factor: 2.607

4.  Transferrin receptor is necessary for development of erythrocytes and the nervous system.

Authors:  J E Levy; O Jin; Y Fujiwara; F Kuo; N C Andrews
Journal:  Nat Genet       Date:  1999-04       Impact factor: 38.330

5.  In vivo fate-tracing studies using the Scl stem cell enhancer: embryonic hematopoietic stem cells significantly contribute to adult hematopoiesis.

Authors:  Joachim R Göthert; Sonja E Gustin; Mark A Hall; Anthony R Green; Berthold Göttgens; David J Izon; C Glenn Begley
Journal:  Blood       Date:  2004-12-14       Impact factor: 22.113

6.  Bcl-x(L) prevents apoptosis of late-stage erythroblasts but does not mediate the antiapoptotic effect of erythropoietin.

Authors:  Melissa M Rhodes; Prapaporn Kopsombut; Maurice C Bondurant; James O Price; Mark J Koury
Journal:  Blood       Date:  2005-05-17       Impact factor: 22.113

7.  Generation of a conditional knockout allele for the Janus kinase 2 (Jak2) gene in mice.

Authors:  Andrea Krempler; Yongyue Qi; Aleata A Triplett; Jianqiong Zhu; Hallgeir Rui; Kay-Uwe Wagner
Journal:  Genesis       Date:  2004-09       Impact factor: 2.487

8.  Ligand-activated site-specific recombination in mice.

Authors:  R Feil; J Brocard; B Mascrez; M LeMeur; D Metzger; P Chambon
Journal:  Proc Natl Acad Sci U S A       Date:  1996-10-01       Impact factor: 11.205

9.  Conditional deletion of Jak2 reveals an essential role in hematopoiesis throughout mouse ontogeny: implications for Jak2 inhibition in humans.

Authors:  Sung O Park; Heather L Wamsley; Kyungmi Bae; Zhongbo Hu; Xiaomiao Li; Se-woon Choe; William B Slayton; S Paul Oh; Kay-Uwe Wagner; Peter P Sayeski
Journal:  PLoS One       Date:  2013-03-27       Impact factor: 3.240

10.  Conditional deletion of the Bcl-x gene from erythroid cells results in hemolytic anemia and profound splenomegaly.

Authors:  K U Wagner; E Claudio; E B Rucker; G Riedlinger; C Broussard; P L Schwartzberg; U Siebenlist; L Hennighausen
Journal:  Development       Date:  2000-11       Impact factor: 6.868
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  21 in total

Review 1.  Regulating billions of blood platelets: glycans and beyond.

Authors:  Renata Grozovsky; Silvia Giannini; Hervé Falet; Karin M Hoffmeister
Journal:  Blood       Date:  2015-09-01       Impact factor: 22.113

Review 2.  Myeloproliferative neoplasm stem cells.

Authors:  Adam J Mead; Ann Mullally
Journal:  Blood       Date:  2017-02-03       Impact factor: 22.113

Review 3.  Novel mechanisms of platelet clearance and thrombopoietin regulation.

Authors:  Renata Grozovsky; Silvia Giannini; Hervé Falet; Karin M Hoffmeister
Journal:  Curr Opin Hematol       Date:  2015-09       Impact factor: 3.284

4.  H3K27 Methylation Dynamics during CD4 T Cell Activation: Regulation of JAK/STAT and IL12RB2 Expression by JMJD3.

Authors:  Sarah A LaMere; Ryan C Thompson; Xiangzhi Meng; H Kiyomi Komori; Adam Mark; Daniel R Salomon
Journal:  J Immunol       Date:  2017-09-25       Impact factor: 5.422

5.  Genetic studies reveal an unexpected negative regulatory role for Jak2 in thrombopoiesis.

Authors:  Sara C Meyer; Matthew D Keller; Brittany A Woods; Lindsay M LaFave; Lennart Bastian; Maria Kleppe; Neha Bhagwat; Sachie Marubayashi; Ross L Levine
Journal:  Blood       Date:  2014-08-12       Impact factor: 22.113

Review 6.  Overview of Transgenic Mouse Models of Myeloproliferative Neoplasms (MPNs).

Authors:  Andrew Dunbar; Abbas Nazir; Ross Levine
Journal:  Curr Protoc Pharmacol       Date:  2017-06-22

7.  The Ashwell-Morell receptor regulates hepatic thrombopoietin production via JAK2-STAT3 signaling.

Authors:  Renata Grozovsky; Antonija Jurak Begonja; Kaifeng Liu; Gary Visner; John H Hartwig; Hervé Falet; Karin M Hoffmeister
Journal:  Nat Med       Date:  2014-12-08       Impact factor: 53.440

Review 8.  Glycans and the platelet life cycle.

Authors:  Renhao Li; Karin M Hoffmeister; Hervé Falet
Journal:  Platelets       Date:  2016-05-02       Impact factor: 3.862

Review 9.  Platelet clearance by the hepatic Ashwell-Morrell receptor: mechanisms and biological significance.

Authors:  Karin M Hoffmeister; Hervé Falet
Journal:  Thromb Res       Date:  2016-05       Impact factor: 3.944

Review 10.  The molecular regulation of Janus kinase (JAK) activation.

Authors:  Jeffrey J Babon; Isabelle S Lucet; James M Murphy; Nicos A Nicola; Leila N Varghese
Journal:  Biochem J       Date:  2014-08-15       Impact factor: 3.857
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