| Literature DB >> 24508818 |
Yu Long Han1, Shuqi Wang2, Xiaohui Zhang1, Yuhui Li1, Guoyou Huang1, Hao Qi3, Belinda Pingguan-Murphy4, Yinghui Li5, Tian Jian Lu6, Feng Xu7.
Abstract
Regenerative medicine has rapidly evolved over the past decade owing to its potential applications to improve human health. Targeted differentiations of stem cells promise to regenerate a variety of tissues and/or organs despite significant challenges. Recent studies have demonstrated the vital role of the physical microenvironment in regulating stem cell fate and improving differentiation efficiency. In this review, we summarize the main physical cues that are crucial for controlling stem cell differentiation. Recent advances in the technologies for the construction of physical microenvironment and their implications in controlling stem cell fate are also highlighted.Entities:
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Year: 2014 PMID： 24508818 DOI： 10.1016/j.drudis.2014.01.015
Source DB: PubMed Journal: Drug Discov Today ISSN： 1359-6446 Impact factor: 7.851