Literature DB >> 24502805

How plausible is a link between HSV-1 infection and Alzheimer's disease?

Simone Agostini1, Mario Clerici, Roberta Mancuso.   

Abstract

Alzheimer's disease is a leading cause of dementia with a multifactorial and still barely understood etiology. A growing body of epidemiologic and experimental data support a role for infectious agents in this process; herpes simplex virus 1 (HSV-1), in particular, is a strong suspect. We briefly summarize the data pointing at a pathogenic role for HSV-1 in the development of Alzheimer's disease and review results indicating that antiviral might be beneficial in the therapy of this condition.

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Year:  2014        PMID： 24502805     DOI： 10.1586/14787210.2014.887442

Source DB:  PubMed          Journal:  Expert Rev Anti Infect Ther        ISSN： 1478-7210            Impact factor:   5.091


  10 in total

Review 1.  The Role of PICALM in Alzheimer's Disease.

Authors:  Wei Xu; Lan Tan; Jin-Tai Yu
Journal:  Mol Neurobiol       Date:  2014-09-04       Impact factor: 5.590

Review 2.  Neuroinflammation, Gut Microbiome, and Alzheimer's Disease.

Authors:  Li Lin; Li Juan Zheng; Long Jiang Zhang
Journal:  Mol Neurobiol       Date:  2018-03-09       Impact factor: 5.590

Review 3.  The potential importance of myeloid-derived suppressor cells (MDSCs) in the pathogenesis of Alzheimer's disease.

Authors:  Antero Salminen; Kai Kaarniranta; Anu Kauppinen
Journal:  Cell Mol Life Sci       Date:  2018-05-19       Impact factor: 9.261

4.  Probiotics ameliorate intestinal pathophysiology in a mouse model of Alzheimer's disease.

Authors:  Harpreet Kaur; Kumi Nagamoto-Combs; Svetlana Golovko; Mikhail Y Golovko; Marilyn G Klug; Colin Kelly Combs
Journal:  Neurobiol Aging       Date:  2020-04-18       Impact factor: 4.673

5.  Pathogenic microbes, the microbiome, and Alzheimer's disease (AD).

Authors:  James M Hill; Christian Clement; Aileen I Pogue; Surjyadipta Bhattacharjee; Yuhai Zhao; Walter J Lukiw
Journal:  Front Aging Neurosci       Date:  2014-06-16       Impact factor: 5.750

6.  Relationship between herpes simplex virus-1-specific antibody titers and cortical brain damage in Alzheimer's disease and amnestic mild cognitive impairment.

Authors:  Roberta Mancuso; Francesca Baglio; Simone Agostini; Monia Cabinio; Maria M Laganà; Ambra Hernis; Nicolò Margaritella; Franca R Guerini; Milena Zanzottera; Raffaello Nemni; Mario Clerici
Journal:  Front Aging Neurosci       Date:  2014-10-15       Impact factor: 5.750

7.  Association between human herpesvirus infections and dementia or mild cognitive impairment: a systematic review protocol.

Authors:  Charlotte Warren-Gash; Harriet Forbes; Judith Breuer; Andrew C Hayward; Angelique Mavrodaris; Basil H Ridha; Martin Rossor; Sara L Thomas; Liam Smeeth
Journal:  BMJ Open       Date:  2017-06-23       Impact factor: 2.692

Review 8.  Alzheimer's Gone Viral: Could Herpes Simplex Virus Type-1 Be Stealing Your Memories?

Authors:  Rhutuja Khokale; Ayesha Kang; Keri-Ann R Buchanan-Peart; Maxine L Nelson; Oluwatayo J Awolumate; Ivan Cancarevic
Journal:  Cureus       Date:  2020-11-27

Review 9.  Overwhelming Evidence for a Major Role for Herpes Simplex Virus Type 1 (HSV1) in Alzheimer's Disease (AD); Underwhelming Evidence against.

Authors:  Ruth F Itzhaki
Journal:  Vaccines (Basel)       Date:  2021-06-21

Review 10.  Neuroinflammation and Infection: Molecular Mechanisms Associated with Dysfunction of Neurovascular Unit.

Authors:  Abolghasem Tohidpour; Andrey V Morgun; Elizaveta B Boitsova; Natalia A Malinovskaya; Galina P Martynova; Elena D Khilazheva; Natalia V Kopylevich; Galina E Gertsog; Alla B Salmina
Journal:  Front Cell Infect Microbiol       Date:  2017-06-20       Impact factor: 5.293
  10 in total

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