OBJECTIVE: The objective of this study was to determine the prevalence and distribution of bone erosions detectable by US in patients with early RA (ERA) in comparison with long-standing RA (LSRA), other erosive diseases and healthy controls. METHODS: Thirty patients with ERA and 80 patients with LSRA were consecutively recruited. Thirty patients with PsA, 15 with primary OA, 10 with gout and 20 healthy subjects were included as controls. Bone erosions were investigated at the following anatomical sites: the second and fifth metacarpal heads, the ulnar head and the first and fifth metatarsal heads, bilaterally. Dorsal, volar and lateral aspects were explored on longitudinal and transverse views. RESULTS: At least one US bone erosion was found in 20 (66.7%) of 30 patients with ERA and in 10 (33%) of them it was found on the fifth metatarsal head. Bone erosions were most frequently found on the lateral quadrants of all scanned anatomical sites. If the second and fifth metacarpal heads and the fifth metatarsal head were scanned, an erosive disease could be found in 60% of ERA patients. The first metatarsal head was most frequently involved in the disease control group. CONCLUSION: This study found a high percentage of ERA patients with US bone erosions, with the fifth metatarsal head and the lateral aspects the most frequently involved site and quadrants. US scanning for bone erosions on a few target joints was found feasible and provided information not obtainable with clinical examination.
OBJECTIVE: The objective of this study was to determine the prevalence and distribution of bone erosions detectable by US in patients with early RA (ERA) in comparison with long-standing RA (LSRA), other erosive diseases and healthy controls. METHODS: Thirty patients with ERA and 80 patients with LSRA were consecutively recruited. Thirty patients with PsA, 15 with primary OA, 10 with gout and 20 healthy subjects were included as controls. Bone erosions were investigated at the following anatomical sites: the second and fifth metacarpal heads, the ulnar head and the first and fifth metatarsal heads, bilaterally. Dorsal, volar and lateral aspects were explored on longitudinal and transverse views. RESULTS: At least one US bone erosion was found in 20 (66.7%) of 30 patients with ERA and in 10 (33%) of them it was found on the fifth metatarsal head. Bone erosions were most frequently found on the lateral quadrants of all scanned anatomical sites. If the second and fifth metacarpal heads and the fifth metatarsal head were scanned, an erosive disease could be found in 60% of ERA patients. The first metatarsal head was most frequently involved in the disease control group. CONCLUSION: This study found a high percentage of ERA patients with US bone erosions, with the fifth metatarsal head and the lateral aspects the most frequently involved site and quadrants. US scanning for bone erosions on a few target joints was found feasible and provided information not obtainable with clinical examination.
Authors: Marwin Gutierrez; Cristina Hernandez-Diaz; Lucio Ventura-Rios; Lina María Saldarriaga-Rivera; Santiago Ruta; Magaly Alva; Claudia Mora -Trujillo; Wilkerson Pérez; Henry Terrazas; Rodolfo Del Carmen Arape Toyo; Maritza Quintero; Carla Solano; Oscar Sedano Santiago; Janet Grisel Huamán Sotomayor; Cesar Cefferino; Guillermo E Py; Marcelo J Audisio; Walter Javier Spindler; Horacio Berman; Carla Airoldi; Rómulo Wong; Ana Laura Álvarez Del Castillo Araujo; Mario E Díaz; Carmen Cerón Villaquiran; Rubén Darío Mantilla; José Alexandre Mendonça; Inês Guimarães da Silveira; Aline Defaveri do Prado; Melissa Cláudia Bisi; Violeta Rosario; Jeannette Medrano-Sánchez; Roberto Muñoz-Louis; Ana Cecilia Lozada-Navarro; Araceli Bernal; Maribel Lozano; Carlos Pineda Journal: Clin Rheumatol Date: 2016-08-30 Impact factor: 2.980
Authors: Carlos Acebes; Neil McKay; Anna Ciechomska; Nicola Alcorn; John P Harvie; Barbara Robson; Nico Groenendijk; Moira McDonald; Alison Wilson; Jesus Garrido Journal: Rheumatol Int Date: 2016-11-28 Impact factor: 2.631
Authors: Emilio Filippucci; Edoardo Cipolletta; Riccardo Mashadi Mirza; Marina Carotti; Andrea Giovagnoni; Fausto Salaffi; Marika Tardella; Andrea Di Matteo; Marco Di Carlo Journal: Radiol Med Date: 2019-03-09 Impact factor: 3.469