Literature DB >> 24499319

Phytochemical and medicinal importance of Ginkgo biloba L.

Tapan Kumar Mohanta1, Yasinalli Tamboli, P K Zubaidha.   

Abstract

Ginkgo biloba L., also popularly known as living fossil, possesses a variety of biological and pharmacological activities. The leaf extract of G. biloba L. (EGb 761) has been used for years to treat age-related memory-deficit problems, including Alzheimer's and dementia. Experimental and clinical studies have revealed its beneficial effects on a wide range of pathological conditions including hepatoprotective, photoprotective effects, DNA repair mechanism, antioxidant and anti-inflammatory activities. Recent studies have also suggested that leaf extract of G. biloba L. may exert beneficial effects on cancer. This review focuses on recent scientific evidence of the reported medicinal effects of G. biloba L.

Entities:  

Keywords:  Alzheimer's; EGb 761; Ginkgo biloba L; bilobalide; ginkgolide

Mesh:

Substances:

Year:  2014        PMID: 24499319     DOI: 10.1080/14786419.2013.879303

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  26 in total

1.  Novel analysis of maturation of murine bone-marrow-derived dendritic cells induced by Ginkgo Seed Polysaccharides.

Authors:  Yinghan Chen; Yiming Meng; Yan Cao; Hua Wen; Hong Luo; Xinghua Gao; Fengping Shan
Journal:  Hum Vaccin Immunother       Date:  2015       Impact factor: 3.452

2.  Butanol Extract of Tinospora cordifolia Ameliorates Cognitive Deficits Associated with Glutamate-Induced Excitotoxicity: A Mechanistic Study Using Hippocampal Neurons.

Authors:  Anuradha Sharma; Shikha Kalotra; Payal Bajaj; Harpal Singh; Gurcharan Kaur
Journal:  Neuromolecular Med       Date:  2019-10-12       Impact factor: 3.843

3.  CB1 as a novel target for Ginkgo biloba's terpene trilactone for controlling chemotherapy-induced peripheral neuropathy (CIPN).

Authors:  Farzaneh Samandar; Zeinab Amiri Tehranizadeh; Mohammad Reza Saberi; Jamshidkhan Chamani
Journal:  J Mol Model       Date:  2022-08-31       Impact factor: 2.172

4.  Ginkgolide C Alleviates Myocardial Ischemia/Reperfusion-Induced Inflammatory Injury via Inhibition of CD40-NF-κB Pathway.

Authors:  Rui Zhang; Dan Han; Zhenyu Li; Chengwu Shen; Yahui Zhang; Jun Li; Genquan Yan; Shasha Li; Bo Hu; Jiangbing Li; Ping Liu
Journal:  Front Pharmacol       Date:  2018-02-21       Impact factor: 5.810

5.  Tnfrsf12a-Mediated Atherosclerosis Signaling and Inflammatory Response as a Common Protection Mechanism of Shuxuening Injection Against Both Myocardial and Cerebral Ischemia-Reperfusion Injuries.

Authors:  Ming Lyu; Ying Cui; Tiechan Zhao; Zhaochen Ning; Jie Ren; Xingpiao Jin; Guanwei Fan; Yan Zhu
Journal:  Front Pharmacol       Date:  2018-04-06       Impact factor: 5.810

6.  The efficacy and safety of Ginkgo biloba extract as an adjuvant in type 2 diabetes mellitus patients ineffectively managed with metformin: a double-blind, randomized, placebo-controlled trial.

Authors:  Tavga Ahmed Aziz; Saad Abdulrahman Hussain; Taha Othman Mahwi; Zheen Aorahman Ahmed; Heshu Sulaiman Rahman; Abdullah Rasedee
Journal:  Drug Des Devel Ther       Date:  2018-04-05       Impact factor: 4.162

7.  Extract of Ginkgo Biloba Ameliorates Streptozotocin-Induced Type 1 Diabetes Mellitus and High-Fat Diet-Induced Type 2 Diabetes Mellitus in Mice.

Authors:  Ki-Jong Rhee; Chang Gun Lee; Sung Woo Kim; Dong-Hyeon Gim; Hyun-Cheol Kim; Bae Dong Jung
Journal:  Int J Med Sci       Date:  2015-11-23       Impact factor: 3.738

8.  Extract of Ginkgo biloba exacerbates liver metastasis in a mouse colon cancer Xenograft model.

Authors:  Huan Wang; Xia Wu; Stephane Lezmi; Qian Li; William G Helferich; Yueqing Xu; Hong Chen
Journal:  BMC Complement Altern Med       Date:  2017-12-02       Impact factor: 3.659

9.  In Silico Investigation of the Pharmacological Mechanisms of Beneficial Effects of Ginkgo biloba L. on Alzheimer's Disease.

Authors:  Hongxiang Li; Xiaoyuan Sun; Fan Yu; Lijia Xu; Jianhua Miu; Peigen Xiao
Journal:  Nutrients       Date:  2018-05-10       Impact factor: 5.717

10.  Efficacy and safety of Ginkgo biloba extract as an "add-on" treatment to metformin for patients with metabolic syndrome: a pilot clinical study.

Authors:  Tavga Ahmed Aziz; Saad Abdulrahman Hussain; Taha Othman Mahwi; Zheen Aorahman Ahmed
Journal:  Ther Clin Risk Manag       Date:  2018-07-11       Impact factor: 2.423

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