Literature DB >> 2449464

Use of immunohistochemical staining panel for characterisation of ovarian neoplasms.

P Ashorn1, M Helle, H Helin, R Ashorn, K Krohn.   

Abstract

Eighty five ovarian epithelial and non-epithelial tumours were studied by peroxidase histochemical staining for their reactivity with six monoclonal human milk fat globule (HMFG) antibodies, peanut agglutinin (PNA) lectin, and a monoclonal cytokeratin antibody. HMFG IIIC12 and cytokeratin antibodies distinguished epithelial from non-epithelial tumours. The staining patterns of mucinous and serous tumours were essentially different from each other; poorly differentiated anaplastic carcinomas showed similar antigenic content to that of the serous cystadenocarcinomas. Furthermore, staining with PNA lectin and HMFG antibodies was useful in distinguishing clear cell carcinomas from other malignant epithelial tumours of the ovary.

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Year:  1988        PMID: 2449464      PMCID: PMC1141327          DOI: 10.1136/jcp.41.1.12

Source DB:  PubMed          Journal:  J Clin Pathol        ISSN: 0021-9746            Impact factor:   3.411


  28 in total

1.  A new antigen on the epithelial membrane: its immunoperoxidase localisation in normal and neoplastic tissue.

Authors:  E Heyderman; K Steele; M G Ormerod
Journal:  J Clin Pathol       Date:  1979-01       Impact factor: 3.411

2.  Use of avidin-biotin-peroxidase complex (ABC) in immunoperoxidase techniques: a comparison between ABC and unlabeled antibody (PAP) procedures.

Authors:  S M Hsu; L Raine; H Fanger
Journal:  J Histochem Cytochem       Date:  1981-04       Impact factor: 2.479

Review 3.  Contributions of immunocytochemistry to the diagnosis and study of ovarian neoplasms.

Authors:  R J Kurman; P Ganjei; M Nadji
Journal:  Int J Gynecol Pathol       Date:  1984       Impact factor: 2.762

4.  Tumor markers in the human ovary and its neoplasms. A comparative immunohistochemical study.

Authors:  E J Nouwen; P G Hendrix; S Dauwe; M W Eerdekens; M E De Broe
Journal:  Am J Pathol       Date:  1987-02       Impact factor: 4.307

5.  Expression of intermediate filaments in ovarian and uterine tumors.

Authors:  C Bonazzi del Poggetto; I Virtanen; V P Lehto; T Wahlström; E Saksela
Journal:  Int J Gynecol Pathol       Date:  1983       Impact factor: 2.762

6.  Generation of monoclonal antibodies to human milk-fat globule membrane antigens, with special reference to a precipitable secretory product of breast and ovarian carcinomas.

Authors:  K Krohn; R Ashorn; M Helle
Journal:  Tumour Biol       Date:  1985

Review 7.  Tumor diagnosis by intermediate filament typing: a novel tool for surgical pathology.

Authors:  M Osborn; K Weber
Journal:  Lab Invest       Date:  1983-04       Impact factor: 5.662

8.  Immunopathologic characterization of a monoclonal antibody that recognizes common surface antigens of human ovarian tumors of serous, endometrioid, and clear cell types.

Authors:  S E Kabawat; R C Bast; W R Welch; R C Knapp; R B Colvin
Journal:  Am J Clin Pathol       Date:  1983-01       Impact factor: 2.493

9.  Differentiation antigens expressed by epithelial cells in the lactating breast are also detectable in breast cancers.

Authors:  J Arklie; J Taylor-Papadimitrious; W Bodmer; M Egan; R Millis
Journal:  Int J Cancer       Date:  1981-07-15       Impact factor: 7.396

10.  Cellular differentiation in ovarian sex-cord-stromal and germ-cell tumors studied with antibodies to intermediate-filament proteins.

Authors:  M Miettinen; T Wahlstrom; I Virtanen; A Talerman; C Astengo-Osuna
Journal:  Am J Surg Pathol       Date:  1985-09       Impact factor: 6.394

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  1 in total

1.  Novel population of small tumour-initiating stem cells in the ovaries of women with borderline ovarian cancer.

Authors:  Irma Virant-Klun; Martin Stimpfel
Journal:  Sci Rep       Date:  2016-10-05       Impact factor: 4.379

  1 in total

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