Literature DB >> 2449089

Monoclonal antibodies define antigenic variation in the ID variety of Venezuelan equine encephalitis virus.

R Rico-Hesse1, J T Roehrig, R W Dickerman.   

Abstract

Three monoclonal antibodies were generated that are specific for the E2 glycoprotein of Venezuelan equine encephalitis (VEE) virus and have useful reactivities in an enzyme-linked immunosorbent assay (ELISA). Antibody 1A1B-9 distinguished between the IC (epizootic) and ID (enzootic) varieties of VEE virus by ELISA. Clone 7A1A-1 antibody distinguished the Panamanian prototype virus (3880) from Colombian ID isolates by a 500-fold difference in titer by endpoint ELISA, and it detected antigenic variation in ID isolates from southern Colombia and Ecuador. Antibody 7A3A-4 defined a cryptic antigenic site on the latter two isolates. These monoclonal antibodies complement others in identifying VEE isolates by a simple ELISA.

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Year:  1988        PMID： 2449089     DOI： 10.4269/ajtmh.1988.38.187

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  6 in total

1.  Use of a new synthetic-peptide-derived monoclonal antibody to differentiate between vaccine and wild-type Venezuelan equine encephalomyelitis viruses.

Authors:  J T Roehrig; R A Bolin; A R Hunt; T M Woodward
Journal:  J Clin Microbiol       Date:  1991-03       Impact factor: 5.948

2.  Monoclonal antibodies capable of distinguishing epizootic from enzootic varieties of subtype 1 Venezuelan equine encephalitis viruses in a rapid indirect immunofluorescence assay.

Authors:  J T Roehrig; R A Bolin
Journal:  J Clin Microbiol       Date:  1997-07       Impact factor: 5.948

3.  Repeated emergence of epidemic/epizootic Venezuelan equine encephalitis from a single genotype of enzootic subtype ID virus.

Authors:  A M Powers; M S Oberste; A C Brault; R Rico-Hesse; S M Schmura; J F Smith; W Kang; W P Sweeney; S C Weaver
Journal:  J Virol       Date:  1997-09       Impact factor: 5.103

4.  Resistance to alpha/beta interferons correlates with the epizootic and virulence potential of Venezuelan equine encephalitis viruses and is determined by the 5' noncoding region and glycoproteins.

Authors:  D R Spotts; R M Reich; M A Kalkhan; R M Kinney; J T Roehrig
Journal:  J Virol       Date:  1998-12       Impact factor: 5.103

5.  Emergence of a new epidemic/epizootic Venezuelan equine encephalitis virus in South America.

Authors:  R Rico-Hesse; S C Weaver; J de Siger; G Medina; R A Salas
Journal:  Proc Natl Acad Sci U S A       Date:  1995-06-06       Impact factor: 11.205

Review 6.  Pathogenic Landscape of Transboundary Zoonotic Diseases in the Mexico-US Border Along the Rio Grande.

Authors:  Maria Dolores Esteve-Gassent; Adalberto A Pérez de León; Dora Romero-Salas; Teresa P Feria-Arroyo; Ramiro Patino; Ivan Castro-Arellano; Guadalupe Gordillo-Pérez; Allan Auclair; John Goolsby; Roger Ivan Rodriguez-Vivas; Jose Guillermo Estrada-Franco
Journal:  Front Public Health       Date:  2014-11-17
  6 in total

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