| Literature DB >> 24490761 |
Xian Feng1, Qian Wang, Wei Lin, Guo-Lan Dou, Zhi-Bin Huang, Da-Qing Shi.
Abstract
A highly efficient, catalyst-free synthesis of polysubstituted pyrroles by means of a novel four-component domino reaction of an arylglyoxal monohydrate, an aniline, a dialkyl but-2-ynedioate, and malononitrile is reported. This transformation proceeded via a 6,6a-dihydrofuro[2,3-b]pyrrole as the key intermediate.Entities:
Mesh：
Substances：
Year: 2013 PMID： 24490761 DOI： 10.1021/ol4010382
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005