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Literature DB >> 24488703

The Wnt cries many: Wnt regulation of neurogenesis through tissue patterning, proliferation, and asymmetric cell division.

Abstract

During early development Wnt signaling has a key role in patterning the prospective nervous system by regulation of cell fate specification, cell polarity, and cell migration. Wnt also coordinates the formation of neural circuits on multiple levels such as transcription, cell cycle, and asymmetric cell division. Here we review the latest findings addressing the role of canonical Wnt/β-catenin signaling during developmental and adult neurogenesis; exploring the connection of in vivo data to the recently described Wnt-driven asymmetric stem cell division in vitro. Understanding how Wnt orchestrates these processes in a spatiotemporal manner during corticogenesis will be of crucial importance for the development of new strategies to regenerate neuronal circuits.

Entities: Chemical

Keywords: Wnt; asymmetric cell division; neurogenesis; proliferation; telencephalon

Mesh：

Year: 2014 PMID： 24488703 DOI： 10.1002/dneu.22168

Source DB: PubMed Journal: Dev Neurobiol ISSN： 1932-8451 Impact factor: 3.964

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Cited

27 in total

1. Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.

Authors: Lea Chia-Ling Hsu; Sean Nam; Yi Cui; Ching-Pu Chang; Chia-Fang Wang; Hung-Chih Kuo; Jonathan D Touboul; Shen-Ju Chou
Journal: Proc Natl Acad Sci U S A Date: 2015-09-14 Impact factor: 11.205

2. Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

Authors: Josefine S Witteveen; Marjolein H Willemsen; Thaís C D Dombroski; Nick H M van Bakel; Willy M Nillesen; Josephus A van Hulten; Eric J R Jansen; Dave Verkaik; Hermine E Veenstra-Knol; Conny M A van Ravenswaaij-Arts; Jolien S Klein Wassink-Ruiter; Marie Vincent; Albert David; Cedric Le Caignec; Jolanda Schieving; Christian Gilissen; Nicola Foulds; Patrick Rump; Tim Strom; Kirsten Cremer; Alexander M Zink; Hartmut Engels; Sonja A de Munnik; Jasper E Visser; Han G Brunner; Gerard J M Martens; Rolph Pfundt; Tjitske Kleefstra; Sharon M Kolk
Journal: Nat Genet Date: 2016-07-11 Impact factor: 38.330

3. Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.

Authors: Wen-Hsuan Chang; Si Ho Choi; Byoung-San Moon; Mingyang Cai; Jungmook Lyu; Jinlun Bai; Fan Gao; Ibrahim Hajjali; Zhongfang Zhao; Daniel B Campbell; Leslie P Weiner; Wange Lu
Journal: Proc Natl Acad Sci U S A Date: 2017-11-27 Impact factor: 11.205

4. Tanshinone I Enhances Neurogenesis in the Mouse Hippocampal Dentate Gyrus via Increasing Wnt-3, Phosphorylated Glycogen Synthase Kinase-3β and β-Catenin Immunoreactivities.

Authors: Bai Hui Chen; Joon Ha Park; Jeong Hwi Cho; In Hye Kim; Jae Chul Lee; Tae-Kyeong Lee; Ji Hyeon Ahn; Hyun Jin Tae; Bich Na Shin; Jong-Dai Kim; Il Jun Kang; Moo-Ho Won; Yun Lyul Lee
Journal: Neurochem Res Date: 2016-04-06 Impact factor: 3.996

The Wnt cries many: Wnt regulation of neurogenesis through tissue patterning, proliferation, and asymmetric cell division.

1. Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.

2. Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity.

3. Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.

4. Tanshinone I Enhances Neurogenesis in the Mouse Hippocampal Dentate Gyrus via Increasing Wnt-3, Phosphorylated Glycogen Synthase Kinase-3β and β-Catenin Immunoreactivities.

Review 5. Neural Stem Cells to Cerebral Cortex: Emerging Mechanisms Regulating Progenitor Behavior and Productivity.

6. Priming cancer cells for drug resistance: role of the fibroblast niche.

Review 7. Wnt/β-catenin signaling during early vertebrate neural development.

Review 8. Radial glia in the ventral telencephalon.

Review 9. Canonical and noncanonical Wnt signaling in neural stem/progenitor cells.

10. Identification and Profiling of Environmental Chemicals That Inhibit the TGFβ/SMAD Signaling Pathway.