Literature DB >> 24487787

Prognostic biomarkers in colorectal cancer: where do we stand?

Xavier Sagaert1.   

Abstract

Colorectal cancer remains a major cause of cancer-related death worldwide. One way to reduce its staggering mortality rate and socio-economic burden is to predict outcome based on the aggressiveness of the tumor biology in order to treat patients accordingly to their risk profile. As such, it comes as no surprise that prognostic biomarker discovery is a hot topic in colorectal cancer research. The last two decades have literally produced tons of new data and an avalanche of potential clinically applicable biomarkers. This review explores and summarizes data concerning the prognostic strength and clinical utility of current and future tissue biomarkers in the diagnosis and treatment of colorectal cancer.

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Year:  2014        PMID： 24487787     DOI： 10.1007/s00428-013-1532-z

Source DB:  PubMed          Journal:  Virchows Arch        ISSN： 0945-6317            Impact factor:   4.064


  129 in total

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Journal:  Gut       Date:  2001-06       Impact factor: 23.059

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Journal:  N Engl J Med       Date:  2005-12-22       Impact factor: 91.245

3.  An evaluation of the relationship between lymph node number and staging in pT3 colon cancer using population-based data.

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Journal:  Dis Colon Rectum       Date:  2010-01       Impact factor: 4.585

4.  CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer.

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Journal:  Gut       Date:  2008-10-02       Impact factor: 23.059

Review 5.  Pathology report in colon cancer: what is prognostically important?

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6.  CD8+ T cells infiltrated within cancer cell nests as a prognostic factor in human colorectal cancer.

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Journal:  Cancer Res       Date:  1998-08-15       Impact factor: 12.701

7.  Allelic loss of chromosome 18q and prognosis in colorectal cancer.

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Journal:  N Engl J Med       Date:  1994-07-28       Impact factor: 91.245

8.  Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer.

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Journal:  Clin Cancer Res       Date:  2008-06-01       Impact factor: 12.531

9.  Colon cancer molecular subtypes identified by expression profiling and associated to stroma, mucinous type and different clinical behavior.

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Journal:  BMC Cancer       Date:  2012-06-19       Impact factor: 4.430

Review 10.  Epithelial mesenchymal transition and tumor budding in aggressive colorectal cancer: tumor budding as oncotarget.

Authors:  Inti Zlobec; Alessandro Lugli
Journal:  Oncotarget       Date:  2010-11
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  11 in total

1.  Prognostic biomarkers: an introduction.

Authors:  Fred T Bosman; Lawrence D True
Journal:  Virchows Arch       Date:  2014-02-22       Impact factor: 4.064

2.  Overexpression of c-Myb is associated with suppression of distant metastases in colorectal carcinoma.

Authors:  Michal Tichý; Lucia Knopfová; Jiří Jarkovský; Lucie Pekarčíková; Lenka Veverková; Petr Vlček; Jana Katolická; Ivan Čapov; Markéta Hermanová; Jan Šmarda; Petr Beneš
Journal:  Tumour Biol       Date:  2016-02-12

Review 3.  Telomeres and telomerase in the clinical management of colorectal cancer.

Authors:  C Piñol-Felis; T Fernández-Marcelo; J Viñas-Salas; C Valls-Bautista
Journal:  Clin Transl Oncol       Date:  2016-10-19       Impact factor: 3.405

4.  Inclusion of cytological features in tumor grading improves prognostic stratification of patients with colorectal cancer.

Authors:  Annika Resch; Lars Harbaum; Marion J Pollheimer; Peter Kornprat; Richard A Lindtner; Cord Langner
Journal:  Int J Colorectal Dis       Date:  2016-01-26       Impact factor: 2.571

5.  Genetic variations in genes of metabolic enzymes predict postoperational prognosis of patients with colorectal cancer.

Authors:  Guanglong Dong; Xianli He; Yibing Chen; Haiyan Cao; Jiaojiao Wang; Xiaonan Liu; Shukui Wang; Shaogui Wan; Jinliang Xing
Journal:  Mol Cancer       Date:  2015-09-17       Impact factor: 27.401

Review 6.  Distant Metastasis in Colorectal Cancer Patients-Do We Have New Predicting Clinicopathological and Molecular Biomarkers? A Comprehensive Review.

Authors:  Stanislav Filip; Veronika Vymetalkova; Jiri Petera; Ludmila Vodickova; Ondrej Kubecek; Stanislav John; Filip Cecka; Marketa Krupova; Monika Manethova; Klara Cervena; Pavel Vodicka
Journal:  Int J Mol Sci       Date:  2020-07-24       Impact factor: 5.923

7.  Expression of TMEM16A in Colorectal Cancer and Its Correlation With Clinical and Pathological Parameters.

Authors:  Hongxia Li; Qiwei Yang; Sibo Huo; Zhenwu Du; Fei Wu; Haiyue Zhao; Shifan Chen; Longfei Yang; Zhiming Ma; Yujie Sui
Journal:  Front Oncol       Date:  2021-03-19       Impact factor: 6.244

8.  Cytotoxic T-lymphocyte Antigen-4 (CTLA-4) Gene Polymorphism (rs3087243) Is Related to Risk and Survival in Patients With Colorectal Cancer.

Authors:  Song VAN Nguyen; Levar Shamoun; Kalle Landerholm; Roland E Andersson; Dick Wagsater; Jan Dimberg
Journal:  In Vivo       Date:  2021 Mar-Apr       Impact factor: 2.155

Review 9.  Current approaches for predicting a lack of response to anti-EGFR therapy in KRAS wild-type patients.

Authors:  Tze-Kiong Er; Chih-Chieh Chen; Luis Bujanda; Marta Herreros-Villanueva
Journal:  Biomed Res Int       Date:  2014-06-18       Impact factor: 3.411

10.  Enhanced expression of GABRD predicts poor prognosis in patients with colon adenocarcinoma.

Authors:  Moxin Wu; Keun Young Kim; Won Cheol Park; Han-Seung Ryu; Suck Chei Choi; Min Seob Kim; Ji Yeon Myung; Hyun Seok Choi; Eui Joong Kim; Moon Young Lee
Journal:  Transl Oncol       Date:  2020-09-03       Impact factor: 4.243
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