| Literature DB >> 24487366 |
Takao Saito1, Akira Matsunaga2.
Abstract
Lipoprotein glomerulopathy is an inherited renal disease characterized by unique lipoprotein thrombi in the glomerulus and is associated with the APOE mutation. Hu and colleagues investigated the genetic and clinical features of a large group of patients with lipoprotein glomerulopathy who carried APOE Kyoto, a major APOE variant. Their findings suggest its descent through a founder effect. Fibrate therapy in this group showed favorable results in the patient and renal survival rates.Entities:
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Year: 2014 PMID： 24487366 DOI： 10.1038/ki.2013.404
Source DB: PubMed Journal: Kidney Int ISSN： 0085-2538 Impact factor: 10.612