Literature DB >> 24485446

Golgi feels DNA's pain.

Marco Foiani1, Jiri Bartek2.   

Abstract

The Golgi apparatus consists of disc-like cisternae, stretching around the nucleus through forces exerted by F-actin and the Golgi membrane protein GOLPH3. Farber-Katz et al. now report that DNA damage triggers Golgi dispersal and inhibits vesicular transport through DNA-PK-mediated GOLPH3 phosphorylation, thereby linking the DNA damage response to Golgi regulation.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24485446     DOI： 10.1016/j.cell.2014.01.030

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  6 in total

Review 1.  GOLPH3 links the Golgi, DNA damage, and cancer.

Authors:  Matthew D Buschman; Juliati Rahajeng; Seth J Field
Journal:  Cancer Res       Date:  2015-01-29       Impact factor: 12.701

Review 2.  The DNA-dependent protein kinase: A multifunctional protein kinase with roles in DNA double strand break repair and mitosis.

Authors:  Nicholas Jette; Susan P Lees-Miller
Journal:  Prog Biophys Mol Biol       Date:  2014-12-27       Impact factor: 3.667

3.  GOLPH3 high expression predicts poor prognosis in patients with resected non-small cell lung cancer: an immunohistochemical analysis.

Authors:  Yu Zhang; Minjie Ma; Biao Han
Journal:  Tumour Biol       Date:  2014-08-01

4.  miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness.

Authors:  Qing Zhang; Junlong Zhuang; Yongming Deng; Lin Yang; Wenmin Cao; Wei Chen; Tingsheng Lin; Xiaoyu Lv; Hang Yu; Yanshi Xue; Hongqian Guo
Journal:  Theranostics       Date:  2017-10-17       Impact factor: 11.556

5.  Golgi phosphoprotein 3 induces autophagy and epithelial-mesenchymal transition to promote metastasis in colon cancer.

Authors:  Li-Yun Gong; Ting Tu; Jing Zhu; Ao-Ping Hu; Jun-Wei Song; Jing-Qiang Huang; Yi Yang; Zeyao Zhu; Yu Chen
Journal:  Cell Death Discov       Date:  2022-02-21

6.  SPDL1 Is an Independent Predictor of Patient Outcome in Colorectal Cancer.

Authors:  Anna Klimaszewska-Wiśniewska; Karolina Buchholz; Justyna Durślewicz; Emilly Schlee Villodre; Maciej Gagat; Dariusz Grzanka
Journal:  Int J Mol Sci       Date:  2022-02-05       Impact factor: 5.923
  6 in total

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