Literature DB >> 24484877

Animal microsurgery using microfluidics.

Jeffrey N Stirman1, Bethany Harker2, Hang Lu3, Matthew M Crane4.   

Abstract

Small multicellular genetic organisms form a central part of modern biological research. Using these small organisms provides significant advantages in genetic tractability, manipulation, lifespan and cost. Although the small size is generally advantageous, it can make procedures such as surgeries both time consuming and labor intensive. Over the past few years there have been dramatic improvements in microfluidic technologies that enable significant improvements in microsurgery and interrogation of small multicellular model organisms.
Copyright © 2013 Elsevier Ltd. All rights reserved.

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Year:  2013        PMID: 24484877      PMCID: PMC3912467          DOI: 10.1016/j.copbio.2013.08.007

Source DB:  PubMed          Journal:  Curr Opin Biotechnol        ISSN: 0958-1669            Impact factor:   9.740


  50 in total

1.  High-throughput study of synaptic transmission at the neuromuscular junction enabled by optogenetics and microfluidics.

Authors:  Jeffrey N Stirman; Martin Brauner; Alexander Gottschalk; Hang Lu
Journal:  J Neurosci Methods       Date:  2010-06-09       Impact factor: 2.390

2.  Large-scale in vivo femtosecond laser neurosurgery screen reveals small-molecule enhancer of regeneration.

Authors:  Chrysanthi Samara; Christopher B Rohde; Cody L Gilleland; Stephanie Norton; Stephen J Haggarty; Mehmet Fatih Yanik
Journal:  Proc Natl Acad Sci U S A       Date:  2010-10-11       Impact factor: 11.205

3.  Axonal regeneration proceeds through specific axonal fusion in transected C. elegans neurons.

Authors:  Brent Neumann; Ken C Q Nguyen; David H Hall; Adela Ben-Yakar; Massimo A Hilliard
Journal:  Dev Dyn       Date:  2011-03-17       Impact factor: 3.780

4.  Construction of a femtosecond laser microsurgery system.

Authors:  Joseph D Steinmeyer; Cody L Gilleland; Carlos Pardo-Martin; Matthew Angel; Christopher B Rohde; Mark A Scott; Mehmet Fatih Yanik
Journal:  Nat Protoc       Date:  2010-02-11       Impact factor: 13.491

5.  High-throughput in vivo vertebrate screening.

Authors:  Carlos Pardo-Martin; Tsung-Yao Chang; Bryan Kyo Koo; Cody L Gilleland; Steven C Wasserman; Mehmet Fatih Yanik
Journal:  Nat Methods       Date:  2010-07-18       Impact factor: 28.547

6.  Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans.

Authors:  Andrew M Leifer; Christopher Fang-Yen; Marc Gershow; Mark J Alkema; Aravinthan D T Samuel
Journal:  Nat Methods       Date:  2011-01-16       Impact factor: 28.547

7.  Real-time multimodal optical control of neurons and muscles in freely behaving Caenorhabditis elegans.

Authors:  Jeffrey N Stirman; Matthew M Crane; Steven J Husson; Sebastian Wabnig; Christian Schultheis; Alexander Gottschalk; Hang Lu
Journal:  Nat Methods       Date:  2011-01-16       Impact factor: 28.547

8.  In vivo laser axotomy in C. elegans.

Authors:  Alexandra B Byrne; Tyson J Edwards; Marc Hammarlund
Journal:  J Vis Exp       Date:  2011-05-19       Impact factor: 1.355

9.  A microfluidic array for large-scale ordering and orientation of embryos.

Authors:  Kwanghun Chung; Yoosik Kim; Jitendra S Kanodia; Emily Gong; Stanislav Y Shvartsman; Hang Lu
Journal:  Nat Methods       Date:  2010-12-26       Impact factor: 28.547

10.  V3D enables real-time 3D visualization and quantitative analysis of large-scale biological image data sets.

Authors:  Hanchuan Peng; Zongcai Ruan; Fuhui Long; Julie H Simpson; Eugene W Myers
Journal:  Nat Biotechnol       Date:  2010-03-14       Impact factor: 54.908

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  1 in total

1.  A perspective on optical developments in microfluidic platforms for Caenorhabditis elegans research.

Authors:  Guillaume Aubry; Hang Lu
Journal:  Biomicrofluidics       Date:  2014-02-13       Impact factor: 2.800

  1 in total

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