Literature DB >> 24466562

Koch Institute Symposium on Cancer Immunology and Immunotherapy.

Adam Drake1, Nikhil S Joshi1, Gregory L Szeto1, Eric Zhu2, Herman N Eisen3, Darrell J Irvine4.   

Abstract

The 12th annual summer symposium of The Koch Institute for Integrative Cancer Research at MIT was held in Cambridge, MA, on June 14th, 1023. The symposium entitled "Cancer Immunology and Immunotherapy" focused on recent advances in preclinical research in basic immunology and biomedical engineering, and their clinical application in cancer therapies. The day-long gathering also provided a forum for discussion and potential collaborations between engineers and clinical investigators. The major topics presented include: (i) enhancement of adoptive cell therapy by engineering to improve the ability and functionality of T-cells against tumor cells; (ii) current therapies using protein and antibody therapeutics to modulate endogenous anti-tumor immunity; and (iii) new technologies to identify molecular targets and assess therapeutic efficacy, and devices to control and target drug delivery more effectively and efficiently.

Entities:  

Year:  2013        PMID: 24466562      PMCID: PMC3897860          DOI: 10.1158/2326-6066.CIR-13-0116

Source DB:  PubMed          Journal:  Cancer Immunol Res        ISSN: 2326-6066            Impact factor:   11.151


  45 in total

1.  Development of a human adaptive immune system in cord blood cell-transplanted mice.

Authors:  Elisabetta Traggiai; Laurie Chicha; Luca Mazzucchelli; Lucio Bronz; Jean-Claude Piffaretti; Antonio Lanzavecchia; Markus G Manz
Journal:  Science       Date:  2004-04-02       Impact factor: 47.728

2.  Perspective: assembly line immunotherapy.

Authors:  Bruce L Levine; Carl H June
Journal:  Nature       Date:  2013-06-27       Impact factor: 49.962

3.  Durable cancer regression off-treatment and effective reinduction therapy with an anti-PD-1 antibody.

Authors:  Evan J Lipson; William H Sharfman; Charles G Drake; Ira Wollner; Janis M Taube; Robert A Anders; Haiying Xu; Sheng Yao; Alice Pons; Lieping Chen; Drew M Pardoll; Julie R Brahmer; Suzanne L Topalian
Journal:  Clin Cancer Res       Date:  2012-11-20       Impact factor: 12.531

Review 4.  Humanized mice for immune system investigation: progress, promise and challenges.

Authors:  Leonard D Shultz; Michael A Brehm; J Victor Garcia-Martinez; Dale L Greiner
Journal:  Nat Rev Immunol       Date:  2012-10-12       Impact factor: 53.106

5.  Massively parallel detection of gene expression in single cells using subnanolitre wells.

Authors:  Yuan Gong; Adebola O Ogunniyi; J Christopher Love
Journal:  Lab Chip       Date:  2010-08-04       Impact factor: 6.799

Review 6.  Blockade of the B7-H1/PD-1 pathway for cancer immunotherapy.

Authors:  Dallas B Flies; Britt J Sandler; Mario Sznol; Lieping Chen
Journal:  Yale J Biol Med       Date:  2011-12

7.  Multidimensional analysis of the frequencies and rates of cytokine secretion from single cells by quantitative microengraving.

Authors:  Qing Han; Elizabeth M Bradshaw; Björn Nilsson; David A Hafler; J Christopher Love
Journal:  Lab Chip       Date:  2010-04-08       Impact factor: 6.799

8.  Generation of a humanized mouse model with both human immune system and liver cells to model hepatitis C virus infection and liver immunopathogenesis.

Authors:  Moses T Bility; Liguo Zhang; Michael L Washburn; T Anthony Curtis; Grigoriy I Kovalev; Lishan Su
Journal:  Nat Protoc       Date:  2012-08-09       Impact factor: 13.491

9.  Safety, activity, and immune correlates of anti-PD-1 antibody in cancer.

Authors:  Suzanne L Topalian; F Stephen Hodi; Julie R Brahmer; Scott N Gettinger; David C Smith; David F McDermott; John D Powderly; Richard D Carvajal; Jeffrey A Sosman; Michael B Atkins; Philip D Leming; David R Spigel; Scott J Antonia; Leora Horn; Charles G Drake; Drew M Pardoll; Lieping Chen; William H Sharfman; Robert A Anders; Janis M Taube; Tracee L McMiller; Haiying Xu; Alan J Korman; Maria Jure-Kunkel; Shruti Agrawal; Daniel McDonald; Georgia D Kollia; Ashok Gupta; Jon M Wigginton; Mario Sznol
Journal:  N Engl J Med       Date:  2012-06-02       Impact factor: 91.245

10.  Adaptive immunity maintains occult cancer in an equilibrium state.

Authors:  Catherine M Koebel; William Vermi; Jeremy B Swann; Nadeen Zerafa; Scott J Rodig; Lloyd J Old; Mark J Smyth; Robert D Schreiber
Journal:  Nature       Date:  2007-11-18       Impact factor: 49.962

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