Literature DB >> 2446620

The homology of complement factor C8 gamma chain and alpha-1-microglobulin.

L T Hunt1, A Elzanowski, W C Barker.   

Abstract

The sequence of the complement factor C8 gamma chain shares a remarkable degree of similarity with that of alpha-1-microglobulin, a member of the alpha-2u-globulin superfamily. This superfamily comprises a diverse group of distantly related animal proteins possessing characteristic structural features and similar functions. Comparison of the C8 gamma chain with these proteins supports its homology to them and suggests a possible functional role.

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Year:  1987        PMID: 2446620     DOI: 10.1016/0006-291x(87)91636-6

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN: 0006-291X            Impact factor:   3.575


  1 in total

1.  Genetic deficiency of complement component C8 in the rabbit: evidence of a translational defect in expression of the alpha-gamma subunit.

Authors:  M Komatsu; K Yamamoto; H Mikami; J M Sodetz
Journal:  Biochem Genet       Date:  1991-06       Impact factor: 1.890

  1 in total

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