Cristina García-Navarro1, Isabel García2, Gabriela Medín3, José Tomás Ramos-Amador4, Marisa Navarro-Gómez3, M José Mellado-Peña2, M I de José Gómez5, Marisol Cortés4, Berta Zamora Crespo6, M Angeles Muñoz-Fernandez7, Daniel Blázquez Gamero8, M Isabel González-Tomé9. 1. Servicio de Inmunodeficiencias e Infecciosas pediátricas, Hospital Universitario 12 de Octubre, Madrid, España; Sección de Neuropsicología, Servicio de Pediatría, Hospital Universitario 12 de Octubre, Madrid, España. 2. Servicio de Pediatría, Hospital Carlos III, Madrid, España. 3. Servicio de Infectología Pediátrica, Hospital General Universitario Gregorio Marañón, Madrid, España. 4. Servicio de Pediatría, Hospital Universitario de Getafe, Getafe, España. 5. Servicio de Infecciosas pediátricas, Hospital Universitario La Paz, Madrid, España. 6. Sección de Neuropsicología, Servicio de Pediatría, Hospital Universitario 12 de Octubre, Madrid, España. 7. Servicio de Inmunología, Hospital General Universitario Gregorio Marañón, Madrid, España. 8. Servicio de Inmunodeficiencias e Infecciosas pediátricas, Hospital Universitario 12 de Octubre, Madrid, España. 9. Servicio de Inmunodeficiencias e Infecciosas pediátricas, Hospital Universitario 12 de Octubre, Madrid, España. Electronic address: maribelgt@hotmail.com.
Abstract
INTRODUCTION: Thanks to advances in antiretroviral treatment, children with HIV infections through vertical transmission have improved their life expectancy. However, new challenges have emerged. We propose this study in order to determine the psychosocial aspects and knowledge of infections in a cohort of adolescents with vertically transmitted HIV infections. METHODS: Patients with vertically-acquired HIV infection between 12 and 19 years old were included. Data were obtained through semi-structured interviews and a Strengths and Difficulties Questionnaire for emotional and behavioral disorders screening. RESULTS: We evaluated 96 patients (58% females) with a median age of 15 years (11-19.1) and a median age at diagnosis of 1.70 years (0-12.2). The median CD4 count was 626cells/mm(3) (132-998), and the viral load was<50cp/ml in 72% of patients. Among them, 90% attended school and 60% repeated at least one course. Although 81% of them knew of their diagnosis, only 30% understood their disease, with 18.2% having discussed it with friends. Six unwanted pregnancies occurred during the study period. Strengths and Difficulties Questionnaire showed hyperactivity risk in 33%. CONCLUSION: A high percentage of adolescents show difficulties in several areas (disease knowledge, peer relationship, school failure...) that can have an impact on their adult lives. Further studies are needed to evaluate their origin and development in depth, as well as interventions to modify this situation.
INTRODUCTION: Thanks to advances in antiretroviral treatment, children with HIV infections through vertical transmission have improved their life expectancy. However, new challenges have emerged. We propose this study in order to determine the psychosocial aspects and knowledge of infections in a cohort of adolescents with vertically transmitted HIV infections. METHODS:Patients with vertically-acquired HIV infection between 12 and 19 years old were included. Data were obtained through semi-structured interviews and a Strengths and Difficulties Questionnaire for emotional and behavioral disorders screening. RESULTS: We evaluated 96 patients (58% females) with a median age of 15 years (11-19.1) and a median age at diagnosis of 1.70 years (0-12.2). The median CD4 count was 626cells/mm(3) (132-998), and the viral load was<50cp/ml in 72% of patients. Among them, 90% attended school and 60% repeated at least one course. Although 81% of them knew of their diagnosis, only 30% understood their disease, with 18.2% having discussed it with friends. Six unwanted pregnancies occurred during the study period. Strengths and Difficulties Questionnaire showed hyperactivity risk in 33%. CONCLUSION: A high percentage of adolescents show difficulties in several areas (disease knowledge, peer relationship, school failure...) that can have an impact on their adult lives. Further studies are needed to evaluate their origin and development in depth, as well as interventions to modify this situation.
Authors: Isabel Cuéllar-Flores; Talía Saínz; Carlos Velo; María Isabel González-Tomé; Cristina García-Navarro; Carolina Fernández-Mcphee; Sara Guillén; José Tomás Ramos; Pilar Miralles; Rafael Rubio; José Ignacio Bernardino; Luis Prieto; Pablo Rojo; Santiago Jiménez de Ory; Maria Luisa Navarro Journal: World J Pediatr Date: 2019-07-08 Impact factor: 2.764
Authors: Sarah M Johnson; Cecilia Piñera; Elizabeth Whittaker; Natalie Kirkhope; Onn M Kon; Giovanni Satta; Maria Elvira Balcells; Caroline Foster Journal: Clin Drug Investig Date: 2022-05-16 Impact factor: 3.580
Authors: Dora Estripeaut; Kathia Luciani; Ricardo García; Rita Banús; Trina María Aguais; Edilma Berrío; Alma Jenkins; Sharene Smoot Journal: AIDS Care Date: 2016-03
Authors: C García-Navarro; S Jimenez de Ory; C Velo Higueras; B Zamora; L Prieto; J T Ramos; M L Navarro; L Escosa-García; R Jurado-Barba; Dolores Falcón; David Moreno; M I González-Tomé Journal: Heliyon Date: 2020-04-25
Authors: Lynn A Hendricks; Taryn Young; Susanna S Van Wyk; Catharina Matheï; Karin Hannes Journal: Int J Environ Res Public Health Date: 2022-09-08 Impact factor: 4.614