Isabel Cuéllar-Flores1, Talía Saínz2,3, Carlos Velo4, María Isabel González-Tomé5, Cristina García-Navarro4, Carolina Fernández-Mcphee6, Sara Guillén7, José Tomás Ramos1, Pilar Miralles8, Rafael Rubio9, José Ignacio Bernardino10, Luis Prieto4, Pablo Rojo4, Santiago Jiménez de Ory11, Maria Luisa Navarro6,11,12,13. 1. Pediatric Department, Hospital Clínico San Carlos, Madrid, Spain. 2. Infectious Diseases Service, Paed Department, Hospital La Paz, Madrid, Spain. 3. La Paz Research Institute (IdiPAZ), Madrid, Spain. 4. Infectious Diseases Service, Paed Department, Hospital 12 de Octubre, Madrid, Spain. 5. Infectious Diseases Service, Paed Department, Hospital 12 de Octubre, Madrid, Spain. maribelgt@hotmail.com. 6. Infectious Diseases Service, Paed Department, H. Gregorio Marañón, Madrid, Spain. 7. Paed Department, Hospital de Getafe, Madrid, Spain. 8. Infectious Diseases Service, H. Gregorio Marañón, Madrid, Spain. 9. HIV Service, Hospital 12 de Octubre, Madrid, Spain. 10. Infectious Diseases Service, Hospital La Paz, Madrid, Spain. 11. Instituto de Investigación Sanitaria Hospital Gregorio Marañón (IiSGM), Madrid, Spain. 12. Universidad Complutense de Madrid, Madrid, Spain. 13. Translational Research Network in Pediatric Infectious Diseases (RITIP), Madrid, Spain.
Abstract
BACKGROUND: Studies investigating health-related quality of life (HRQoL) in youth with perinatally acquired HIV (PHIV+) are scarce. This study aimed to compare HRQoL of PHIV+ to sociodemographic-matched youth not living with HIV (HIV-), Spanish general youth population, and to explore associations between sociodemographic variables, drug consumption, and HRQoL. METHODS: PHIV+ youth were randomly selected from CoRISpe database (Cohort of the Spanish Pediatric HIV Network). HRQoL was evaluated by SF-12v2. RESULTS: Thirty-nine PHIV+ youth (mean age: 23.36 years, SD = 3.83) and thirty-nine HIV- youth (mean age: 22.97 years, SD = 3.80) participated in this study. PHIV+ obtained lower scores in SF-12 physical health subscale (PCS) than HIV- (P = 0.001) and Spanish general youth population (P = 0.006). PHIV+ had lower scores on the mental health subscale (MCS) than the Spanish general youth population (P < 0.001). PHIV+ who were at school obtained better scores than those were not at school. PHIV+ youth who had used cocaine and cannabis had lower scores in MCS (P = 0.002). CONCLUSIONS: There is a need for HRQoL management in the associated medical follow-up.
BACKGROUND: Studies investigating health-related quality of life (HRQoL) in youth with perinatally acquired HIV (PHIV+) are scarce. This study aimed to compare HRQoL of PHIV+ to sociodemographic-matched youth not living with HIV (HIV-), Spanish general youth population, and to explore associations between sociodemographic variables, drug consumption, and HRQoL. METHODS: PHIV+ youth were randomly selected from CoRISpe database (Cohort of the Spanish Pediatric HIV Network). HRQoL was evaluated by SF-12v2. RESULTS: Thirty-nine PHIV+ youth (mean age: 23.36 years, SD = 3.83) and thirty-nine HIV- youth (mean age: 22.97 years, SD = 3.80) participated in this study. PHIV+ obtained lower scores in SF-12 physical health subscale (PCS) than HIV- (P = 0.001) and Spanish general youth population (P = 0.006). PHIV+ had lower scores on the mental health subscale (MCS) than the Spanish general youth population (P < 0.001). PHIV+ who were at school obtained better scores than those were not at school. PHIV+ youth who had used cocaine and cannabis had lower scores in MCS (P = 0.002). CONCLUSIONS: There is a need for HRQoL management in the associated medical follow-up.
Entities:
Keywords:
Drug consumption; Health-related quality of life; Mental health; Perinatally acquired HIV youth
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