Literature DB >> 24454115

(7-Chloro-2-oxo-2H-chromen-4-yl)methyl pyrrolidine-1-carbodi-thio-ate.

O Kotresh1, H C Devarajegowda2, Arunkumar Shirahatti1, K Mahesh Kumar1, N M Mahabhaleshwaraiah1.   

Abstract

In the title compound, C15H14ClNO2S2, the 2H-chromene ring system is essentially planar, with a maximum deviation of 0.0133 (10) Å. Three C atoms and their attached H atoms of the pyrrolidine ring are disordered [occupany ratio 0.874 (7):0.126 (7)] with both disorder components adopting a twisted conformation. The dihedral angle between the 2H-chromene ring system and the major occupancy component of the pyrrolidine ring is 89.45 (7)°. In the crystal, inversion dimers linked by pairs of C-H⋯S and C-H⋯O inter-actions generate R (2) 2(24) and R (2) 2(10) loops, respectively. Further C-H⋯O hydrogen bonds link the dimers into [100] chains. C-H⋯π inter-actions also occur and there is very weak π-π stacking [inter-planar spacing = 3.650 (5) Å; centroid-centroid distance = 4.095 (7) Å] between inversion-related chloro-benzene rings.

Entities:  

Year:  2013        PMID: 24454115      PMCID: PMC3884339          DOI: 10.1107/S1600536813028080

Source DB:  PubMed          Journal:  Acta Crystallogr Sect E Struct Rep Online        ISSN: 1600-5368


  6 in total

1.  The antiproliferative effect of coumarins on several cancer cell lines.

Authors:  S Kawaii; Y Tomono; K Ogawa; M Sugiura; M Yano; Y Yoshizawa
Journal:  Anticancer Res       Date:  2001 Mar-Apr       Impact factor: 2.480

Review 2.  Recent progress in the development of coumarin derivatives as potent anti-HIV agents.

Authors:  Donglei Yu; Madoka Suzuki; Lan Xie; Susan L Morris-Natschke; Kuo-Hsiung Lee
Journal:  Med Res Rev       Date:  2003-05       Impact factor: 12.944

3.  The molecularity of the Newman-Kwart rearrangement.

Authors:  Matthew Burns; Guy C Lloyd-Jones; Jonathan D Moseley; Joseph S Renny
Journal:  J Org Chem       Date:  2010-10-01       Impact factor: 4.354

4.  Synthesis of coumarin derivatives with cytotoxic, antibacterial and antifungal activity.

Authors:  Khalid Mohammed Khan; Zafar S Saify; Muhammad Zarrar Khan; Iqbal M Choudhary; Shahnaz Perveen; Zahid H Chohan; Claudiu T Supuran
Journal:  J Enzyme Inhib Med Chem       Date:  2004-08       Impact factor: 5.051

5.  A short history of SHELX.

Authors:  George M Sheldrick
Journal:  Acta Crystallogr A       Date:  2007-12-21       Impact factor: 2.290

6.  (6-Meth-oxy-2-oxo-2H-chromen-4-yl)methyl pyrrolidine-1-carbodithio-ate.

Authors:  N M Mahabaleshwaraiah; K Mahesh Kumar; O Kotresh; Waleed Fadl Ali Al-Eryani; H C Devarajegowda
Journal:  Acta Crystallogr Sect E Struct Rep Online       Date:  2012-04-28
  6 in total

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