Literature DB >> 24453613

Intra-articular bupivacaine or bupivacaine and morphine after ACL reconstruction.

Marcus Vinicius Danieli1, Antonio Cavazzani Neto1, Paulo Adilson Herrera1.   

Abstract

OBJECTIVE: Reconstructive surgery of the ACL is one of the most commonly performed surgeries today and the control of postoperative pain is part of the priorities of the surgeon. Within the arsenal of analgesia we have the intra-articular application of drugs, and the most studied one is bupivacaine with or without morphine. This study compared the application of bupivacaine with or without morphine with a control group after ACL reconstruction with flexor tendon graft.
METHODS: Forty-five patients were randomized into three groups: in group I, 20 ml of saline were applied intra-articularly at the end of the surgery; in group II, 20 ml of bupivacaine 0.25%; and in group III, bupivacaine 0.25% associated with 1 mg of morphine. The groups were assessed for degree of pain by the Visual Analog Scale at 6, 24 and 48 hours postoperatively.
RESULTS: Group III had less pain at all times, but the pain was not as intense in all groups to the point of needing extra medications beyond the established protocol.
CONCLUSION: The intra-articular application of these medications after ACL reconstruction with flexor tendon graft when performed under spinal anesthesia is not useful enough to use regularly. Level of Evidence II, Lesser quality RCT.

Entities:  

Keywords:  Anesthesia & analgesia; Anterior cruciate ligament/surgery; Bupivacaine; Morphine; Pain measurement

Year:  2012        PMID: 24453613      PMCID: PMC3718450          DOI: 10.1590/S1413-78522012000500002

Source DB:  PubMed          Journal:  Acta Ortop Bras        ISSN: 1413-7852            Impact factor:   0.513


  17 in total

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Authors:  G F Khoury; A C Chen; D E Garland; C Stein
Journal:  Anesthesiology       Date:  1992-08       Impact factor: 7.892

2.  Postoperative analgesic effects of an external cooling system and intra-articular bupivacaine/morphine after arthroscopic cruciate ligament surgery.

Authors:  S Brandsson; B Rydgren; T Hedner; B I Eriksson; O Lundin; L Swärd; J Karlsson
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  1996       Impact factor: 4.342

3.  Analgesic effect of intraarticular bupivacaine or morphine after arthroscopic knee surgery: a randomized, prospective, double-blind study.

Authors:  S O Heard; W T Edwards; D Ferrari; D Hanna; P D Wong; A Liland; M M Willock
Journal:  Anesth Analg       Date:  1992-06       Impact factor: 5.108

Review 4.  Pain management in patients who undergo outpatient arthroscopic surgery of the knee.

Authors:  S S Reuben; J Sklar
Journal:  J Bone Joint Surg Am       Date:  2000-12       Impact factor: 5.284

5.  Local and intra-articular infiltration of bupivacaine before surgery: effect on postoperative pain after anterior cruciate ligament reconstruction.

Authors:  J Höher; D Kersten; B Bouillon; E Neugebauer; T Tiling
Journal:  Arthroscopy       Date:  1997-04       Impact factor: 4.772

6.  Intraarticular analgesia after arthroscopic knee surgery: comparison of neostigmine, clonidine, tenoxicam, morphine and bupivacaine.

Authors:  A Alagol; O U Calpur; P Saral Usar; N Turan; Z Pamukcu
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2005-05-24       Impact factor: 4.342

7.  Postarthroscopy analgesia with intraarticular bupivacaine/morphine. A randomized clinical trial.

Authors:  G C Allen; M A St Amand; A C Lui; D H Johnson; M P Lindsay
Journal:  Anesthesiology       Date:  1993-09       Impact factor: 7.892

8.  Intraarticular tramadol-bupivacaine combination prolongs the duration of postoperative analgesia after outpatient arthroscopic knee surgery.

Authors:  Ahed Zeidan; Rida Kassem; Nazih Nahleh; Hilal Maaliki; Mohamad El-Khatib; Michel M R F Struys; Anis Baraka
Journal:  Anesth Analg       Date:  2008-07       Impact factor: 5.108

9.  The effect of bupivacaine and morphine in a coculture model of diarthrodial joints.

Authors:  Alan Anz; Matthew J Smith; Aaron Stoker; Cole Linville; Heather Markway; Keith Branson; James L Cook
Journal:  Arthroscopy       Date:  2009-01-24       Impact factor: 4.772

10.  Analgesia following arthroscopic knee surgery. A controlled study of intra-articular morphine, bupivacaine or both combined.

Authors:  M M McSwiney; G P Joshi; P Kenny; S M McCarroll
Journal:  Anaesth Intensive Care       Date:  1993-04       Impact factor: 1.669

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  4 in total

1.  Single-dose intra-articular bupivacaine plus morphine versus bupivacaine alone after arthroscopic knee surgery: a meta-analysis of randomized controlled trials.

Authors:  Ye Yang; Chao Zeng; Jie Wei; Hui Li; Tuo Yang; Zhen-Han Deng; Yu-Sheng Li; Tu-Bao Yang; Guang-Hua Lei
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2015-08-12       Impact factor: 4.342

2.  Assessment of The Addition of Epinephrine to Intra-articular Bupivacaine for the Control of Acute Pain in Patients underwent to Anterior Cruciate Ligament Reconstruction.

Authors:  Marcos George de Souza Leão; Juscimar Carneiro Nunes; Ivan Tramujas da Costa E Silva; Alan Braga Perfeito; Wagner de Paula Rogério; Rafaela Brasil E Silva Nunes
Journal:  Rev Bras Ortop (Sao Paulo)       Date:  2021-04-19

3.  Single-dose intra-articular bupivacaine plus morphine after knee arthroscopic surgery: a meta-analysis of randomised placebo-controlled studies.

Authors:  Yi-lun Wang; Chao Zeng; Dong-xing Xie; Ye Yang; Jie Wei; Tuo Yang; Hui Li; Guang-hua Lei
Journal:  BMJ Open       Date:  2015-06-15       Impact factor: 2.692

4.  Comparison of intra-articular analgesics in arthroscopic anterior cruciate ligament reconstruction surgeries: A randomized controlled trial.

Authors:  Vijayalakshmi Sivapurapu; Shishir Suranigi Murugharaj; Sai Saran Panathula Venkata
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2017 Jul-Sep
  4 in total

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