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Literature DB >> 2445076

Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids.

S Todo¹, A J Demetris, Y Ueda, O Imventarza, K Okuda, A Casavilla, S Cemaj, A Ghalab, V Mazzaferro, B S Rhoe.

Abstract

The immunosuppressive agent FK permitted increased kidney transplant survival in dogs over a wide dose range, but with weight loss and manifold evidence of toxicity. The best use of FK at low doses was in combination with CyA and Pred.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 1987 PMID： 2445076 PMCID： PMC2903874

Source DB: PubMed Journal: Transplant Proc ISSN： 0041-1345 Impact factor: 1.066

2 in total

1. Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.

Authors: T Ochiai; K Nakajima; M Nagata; T Suzuki; T Asano; T Uematsu; T Goto; S Hori; T Kenmochi; T Nakagoori
Journal: Transplant Proc Date: 1987-02 Impact factor: 1.066

2. IMMUNOSUPPRESSION WITH FR 900506 FOR CANINE KIDNEY AND LIVER TRANSPLANTATION.

Authors: S Todo; L Makowka; T Starzl
Journal: Surg Res Commun Date: 1987-01-01

2 in total

26 in total

1. Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction.

Authors: A C Tsamandas; S M Pham; E C Seaberg; O Pappo; R L Kormos; A Kawai; B P Griffith; A Zeevi; R Duquesnoy; J J Fung; T E Starzl; A J Demetris
Journal: J Heart Lung Transplant Date: 1997-07 Impact factor: 10.247

2. Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications.

Authors: J J Fung; S Todo; A Jain; J McCauley; M Alessiani; C Scotti; T E Starzl
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

3. Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA.

Authors: A Zeevi; G Eiras; F H Bach; J J Fung; S Todo; T Starzl; R J Duquesnoy
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

4. Gastrointestinal and metabolic problems associated with immunosuppression with either CyA or FK 506 in liver transplantation.

Authors: D H Van Thiel; M Iqbal; A Jain; J Fung; S Todo; T E Starzl
Journal: Transplant Proc Date: 1990-02 Impact factor: 1.066

Canine kidney transplantation with FK-506 alone or in combination with cyclosporine and steroids.

1. Effect of a new immunosuppressive agent, FK 506, on heterotopic cardiac allotransplantation in the rat.

2. IMMUNOSUPPRESSION WITH FR 900506 FOR CANINE KIDNEY AND LIVER TRANSPLANTATION.

1. Adult heart transplantation under tacrolimus (FK506) immunosuppression: histopathologic observations and comparison to a cyclosporine-based regimen with lympholytic (ATG) induction.

2. Conversion from cyclosporine to FK 506 in liver allograft recipients with cyclosporine-related complications.

3. Functional differentiation of human cytotoxic T lymphocytes in the presence of FK 506 and CyA.

4. Gastrointestinal and metabolic problems associated with immunosuppression with either CyA or FK 506 in liver transplantation.

5. Pathologic observations in human allograft recipients treated with FK 506.

6. The effect of FK 506 on small intestine allotransplantation in the rat.

7. Species differences in sensitivity of T lymphocytes to immunosuppressive effects of FK 506.

8. Canine total orthotopic small bowel transplantation under FK 506.

9. Pharmacokinetics of cyclosporine and nephrotoxicity in orthotopic liver transplant patients rescued with FK 506.

10. Enhanced liver regeneration in rats treated with 15-deoxyspergualin alone and in combination with FK 506.