| Literature DB >> 24438730 |
Martin A Alpert1, Jad Omran2, Ankit Mehra2, Sivakumar Ardhanari2.
Abstract
Obesity, particularly severe obesity is capable of producing hemodynamic alterations that predispose to changes in cardiac morphology and ventricular function. These include increased cardiac output, left ventricular hypertrophy and diastolic and systolic dysfunction of both ventricles. Facilitated by co-morbidities such as hypertension, the sleep apnea/obesity hypoventilation syndrome, and possibly certain neurohormonal and metabolic alterations, these abnormalities may predispose to left and right heart failure, a disorder known as obesity cardiomyopathy.Entities:
Keywords: BMI; BP; CAD; CBV; CO; Diastolic dysfunction; HF; HTN; High cardiac output; LA; LV; Left ventricular hypertrophy; Obesity; PVR; RAAS; RV; Systolic dysfunction; TG; blood pressure; body mass index; cardiac output; central blood volume; coronary artery disease; heart failure; left atrial or left atrium; left ventricular or left ventricle; peripheral vascular resistance; renin–angiotensin–aldosterone system; right ventricular or right ventricle; systemic hypertension; triglyceride(s)
Mesh：
Year: 2013 PMID： 24438730 DOI： 10.1016/j.pcad.2013.09.003
Source DB: PubMed Journal: Prog Cardiovasc Dis ISSN： 0033-0620 Impact factor: 8.194