Literature DB >> 2442792

[Changes in the serum fraction composition of nucleic acids in radiation injuries. Alterations in an early period after gamma-irradiation of rats].

A S Belokhvostov, S N Lebedev, S S Sherlina.   

Abstract

The content and fractional composition of nucleic acids of blood serum change after lethal (8 Gy) particularly superlethal (100 Gy) gamma-irradiation of rats. This concerns DNA the content of which increases by 7 times 5 h following 100 Gy irradiation. It has been shown by electrophoresis in 0.85% agarose that a heterogeneous DNA fraction with the molecular weight of (1-15) X 10(6) dalton increases. The analysis of the preparation in the polyacrylamide gel has revealed a DNA fraction that is not found in norm: the fraction possesses the electrophoretic mobility corresponding to that of nucleosome DNA.

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Year:  1987        PMID: 2442792

Source DB:  PubMed          Journal:  Radiobiologiia        ISSN: 0033-8192


  4 in total

1.  Alteration of mtDNA copy number, mitochondrial gene expression and extracellular DNA content in mice after irradiation at lethal dose.

Authors:  Edward V Evdokimovsky; Tatjana E Ushakova; Andrej A Kudriavtcev; Ajub I Gaziev
Journal:  Radiat Environ Biophys       Date:  2010-09-03       Impact factor: 1.925

2.  A new biodosimetric method: branched DNA-based quantitative detection of B1 DNA in mouse plasma.

Authors:  L Zhang; M Zhang; S Yang; Y Cao; S Bingrong Zhang; L Yin; Y Tian; Y Ma; A Zhang; P Okunieff; L Zhang
Journal:  Br J Radiol       Date:  2010-08       Impact factor: 3.039

3.  PicoGreen assay of circular DNA for radiation biodosimetry.

Authors:  Steven B Zhang; Shanmin Yang; Sadasivan Vidyasagar; Mei Zhang; Katherine Casey-Sawicki; Chaomei Liu; Liangjie Yin; Lei Zhang; Yongbing Cao; Yeping Tian; Steven Swarts; Bruce M Fenton; Peter Keng; Lurong Zhang; Paul Okunieff
Journal:  Radiat Res       Date:  2015-01-09       Impact factor: 2.841

4.  B1 sequence-based real-time quantitative PCR: a sensitive method for direct measurement of mouse plasma DNA levels after gamma irradiation.

Authors:  Hengshan Zhang; Steven B Zhang; Weimin Sun; Shanmin Yang; Mei Zhang; Wei Wang; Chaomei Liu; Kunzhong Zhang; Steven Swarts; Bruce M Fenton; Peter Keng; David Maguire; Paul Okunieff; Lurong Zhang
Journal:  Int J Radiat Oncol Biol Phys       Date:  2009-08-01       Impact factor: 7.038

  4 in total

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