Literature DB >> 24424785

Shifting wavelengths of ultraweak photon emissions from dying melanoma cells: their chemical enhancement and blocking are predicted by Cosic's theory of resonant recognition model for macromolecules.

Blake T Dotta1, Nirosha J Murugan, Lukasz M Karbowski, Robert M Lafrenie, Michael A Persinger.   

Abstract

During the first 24 h after removal from incubation, melanoma cells in culture displayed reliable increases in emissions of photons of specific wavelengths during discrete portions of this interval. Applications of specific filters revealed marked and protracted increases in infrared (950 nm) photons about 7 h after removal followed 3 h later by marked and protracted increases in near ultraviolet (370 nm) photon emissions. Specific wavelengths within the visible (400 to 800 nm) peaked 12 to 24 h later. Specific activators or inhibitors for specific wavelengths based upon Cosic's resonant recognition model elicited either enhancement or diminishment of photons at the specific wavelength as predicted. Inhibitors or activators predicted for other wavelengths, even within 10 nm, were less or not effective. There is now evidence for quantitative coupling between the wavelength of photon emissions and intrinsic cellular chemistry. The results are consistent with initial activation of signaling molecules associated with infrared followed about 3 h later by growth and protein-structural factors associated with ultraviolet. The greater-than-expected photon counts compared with raw measures through the various filters, which also function as reflective material to other photons, suggest that photons of different wavelengths might be self-stimulatory and could play a significant role in cell-to-cell communication.

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Year:  2014        PMID: 24424785     DOI: 10.1007/s00114-013-1133-3

Source DB:  PubMed          Journal:  Naturwissenschaften        ISSN: 0028-1042


  15 in total

1.  Biophoton emissions from cell cultures: biochemical evidence for the plasma membrane as the primary source.

Authors:  Blake T Dotta; Carly A Buckner; Dianne Cameron; Robert F Lafrenie; Michael A Persinger
Journal:  Gen Physiol Biophys       Date:  2011-09       Impact factor: 1.512

2.  10-20 Joules as a neuromolecular quantum in medicinal chemistry: an alternative approach to myriad molecular pathways?

Authors:  M A Persinger
Journal:  Curr Med Chem       Date:  2010       Impact factor: 4.530

3.  Increased mobility and stem-cell proliferation rate in Dugesia tigrina induced by 880nm light emitting diode.

Authors:  Hsia-Pai Patrick Wu; Michael A Persinger
Journal:  J Photochem Photobiol B       Date:  2010-11-24       Impact factor: 6.252

4.  Low power laser radiation at 685 nm stimulates stem-cell proliferation rate in Dugesia tigrina during regeneration.

Authors:  Sandra Cristina de Souza; Egberto Munin; Leandro Procópio Alves; Miguel Angel Castillo Salgado; Marcos Tadeu Tavares Pacheco
Journal:  J Photochem Photobiol B       Date:  2005-09-01       Impact factor: 6.252

5.  Biophotons as neural communication signals demonstrated by in situ biophoton autography.

Authors:  Yan Sun; Chao Wang; Jiapei Dai
Journal:  Photochem Photobiol Sci       Date:  2010-01-21       Impact factor: 3.982

6.  Biophoton emission.

Authors: 
Journal:  Experientia       Date:  1988-07-15

7.  Ultraweak biochemiluminescence detected from rat hippocampal slices.

Authors:  Y Isojima; T Isoshima; K Nagai; K Kikuchi; H Nakagawa
Journal:  Neuroreport       Date:  1995-03-07       Impact factor: 1.837

Review 8.  Inducible gene expression systems for higher eukaryotic cells.

Authors:  M Gossen; A L Bonin; S Freundlieb; H Bujard
Journal:  Curr Opin Biotechnol       Date:  1994-10       Impact factor: 9.740

Review 9.  Macromolecular bioactivity: is it resonant interaction between macromolecules?--Theory and applications.

Authors:  I Cosic
Journal:  IEEE Trans Biomed Eng       Date:  1994-12       Impact factor: 4.538

10.  Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules.

Authors:  Makoto Mitsunaga; Mikako Ogawa; Nobuyuki Kosaka; Lauren T Rosenblum; Peter L Choyke; Hisataka Kobayashi
Journal:  Nat Med       Date:  2011-11-06       Impact factor: 53.440

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  8 in total

1.  Inverse relationship between photon flux densities and nanotesla magnetic fields over cell aggregates: Quantitative evidence for energetic conservation.

Authors:  Michael A Persinger; Blake T Dotta; Lukasz M Karbowski; Nirosha J Murugan
Journal:  FEBS Open Bio       Date:  2015-05-04       Impact factor: 2.693

2.  Novel Cosic resonance (standing wave) solutions for components of the JAK-STAT cellular signaling pathway: A convergence of spectral density profiles.

Authors:  Lukasz M Karbowski; Nirosha J Murugan; Michael A Persinger
Journal:  FEBS Open Bio       Date:  2015-03-25       Impact factor: 2.693

3.  Biophotonic markers of malignancy: Discriminating cancers using wavelength-specific biophotons.

Authors:  Nirosha J Murugan; Nicolas Rouleau; Lukasz M Karbowski; Michael A Persinger
Journal:  Biochem Biophys Rep       Date:  2017-11-20

4.  Ultraweak Photon Emissions as a Non-Invasive, Early-Malignancy Detection Tool: An In Vitro and In Vivo Study.

Authors:  Nirosha J Murugan; Michael A Persinger; Lukasz M Karbowski; Blake T Dotta
Journal:  Cancers (Basel)       Date:  2020-04-18       Impact factor: 6.639

5.  The code of light: do neurons generate light to communicate and repair?

Authors:  Cecile Moro; Ann Liebert; Catherine Hamilton; Nicolas Pasqual; Glen Jeffery; Jonathan Stone; John Mitrofanis
Journal:  Neural Regen Res       Date:  2022-06       Impact factor: 5.135

Review 6.  The effect of photobiomodulation on the brain during wakefulness and sleep.

Authors:  Cecile Moro; Audrey Valverde; Marjorie Dole; Jaimie Hoh Kam; Catherine Hamilton; Ann Liebert; Brian Bicknell; Alim-Louis Benabid; Pierre Magistretti; John Mitrofanis
Journal:  Front Neurosci       Date:  2022-07-28       Impact factor: 5.152

7.  Environmental Light and Its Relationship with Electromagnetic Resonances of Biomolecular Interactions, as Predicted by the Resonant Recognition Model.

Authors:  Irena Cosic; Drasko Cosic; Katarina Lazar
Journal:  Int J Environ Res Public Health       Date:  2016-06-29       Impact factor: 3.390

8.  Bacterial biophotons as non-local information carriers: Species-specific spectral characteristics of a stress response.

Authors:  Lucas W E Tessaro; Blake T Dotta; Michael A Persinger
Journal:  Microbiologyopen       Date:  2018-10-31       Impact factor: 3.139

  8 in total

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