Literature DB >> 24424533

Gastrointestinal mucositis: the role of MMP-tight junction interactions in tissue injury.

Noor Al-Dasooqi1, Hannah R Wardill, Rachel J Gibson.   

Abstract

Chemotherapy for cancer causes significant gut toxicity known as mucositis. The pathogenesis of mucositis is ill defined. Recent clinical research guidelines have highlighted epithelial junctional complexes as emerging targets within mucositis research. Given the robust biological evidence linking tight junctions and matrix metalloproteinases, key mediators of mucositis, tight junction proteins have received significant attention. Despite this, the link between tight junctions, matrix metalloproteinases and mucositis development is yet to be established. This critical review therefore aims to describe the role of matrix metalloproteinases in mucositis, and how matrix metalloproteinase-dependent tight junction disruption may contribute to the pathobiology of mucositis.

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Year:  2014        PMID： 24424533     DOI： 10.1007/s12253-013-9733-y

Source DB:  PubMed          Journal:  Pathol Oncol Res        ISSN： 1219-4956            Impact factor:   3.201


  65 in total

Review 1.  Regulation of tight junction permeability by intestinal bacteria and dietary components.

Authors:  Dulantha Ulluwishewa; Rachel C Anderson; Warren C McNabb; Paul J Moughan; Jerry M Wells; Nicole C Roy
Journal:  J Nutr       Date:  2011-03-23       Impact factor: 4.798

Review 2.  Chemotherapy-induced gut toxicity: are alterations to intestinal tight junctions pivotal?

Authors:  Hannah R Wardill; Joanne M Bowen; Rachel J Gibson
Journal:  Cancer Chemother Pharmacol       Date:  2012-09-30       Impact factor: 3.333

Review 3.  The structure and regulation of tight junctions.

Authors:  J M Anderson; M S Balda; A S Fanning
Journal:  Curr Opin Cell Biol       Date:  1993-10       Impact factor: 8.382

4.  Glucocorticoid effects on endothelial barrier function in the murine brain endothelial cell line cEND incubated with sera from patients with multiple sclerosis.

Authors:  Kinga G Blecharz; Aiden Haghikia; Mariusz Stasiolek; Niels Kruse; Detlev Drenckhahn; Ralf Gold; Norbert Roewer; Andrew Chan; Carola Y Förster
Journal:  Mult Scler       Date:  2010-03       Impact factor: 6.312

5.  Epithelial transport and barrier function in occludin-deficient mice.

Authors:  J D Schulzke; A H Gitter; J Mankertz; S Spiegel; U Seidler; S Amasheh; M Saitou; S Tsukita; M Fromm
Journal:  Biochim Biophys Acta       Date:  2005-05-15

6.  Methotrexate modulates tight junctions through NF-κB, MEK, and JNK pathways.

Authors:  Stéphanie Beutheu Youmba; Liliana Belmonte; Ludovic Galas; Nabile Boukhettala; Christine Bôle-Feysot; Pierre Déchelotte; Moïse Coëffier
Journal:  J Pediatr Gastroenterol Nutr       Date:  2012-04       Impact factor: 2.839

7.  Irinotecan-induced alterations in intestinal cell kinetics and extracellular matrix component expression in the Dark Agouti rat.

Authors:  Noor Al-Dasooqi; Joanne M Bowen; Rachel J Gibson; Richard M Logan; Andrea M Stringer; Dorothy M Keefe
Journal:  Int J Exp Pathol       Date:  2011-04-05       Impact factor: 1.925

8.  Metalloproteinase mediated occludin cleavage in the cerebral microcapillary endothelium under pathological conditions.

Authors:  Mira Lischper; Simon Beuck; Gokulan Thanabalasundaram; Christian Pieper; Hans-Joachim Galla
Journal:  Brain Res       Date:  2010-03-01       Impact factor: 3.252

9.  Updated clinical practice guidelines for the prevention and treatment of mucositis.

Authors:  Dorothy M Keefe; Mark M Schubert; Linda S Elting; Stephen T Sonis; Joel B Epstein; Judith E Raber-Durlacher; Cesar A Migliorati; Deborah B McGuire; Ronald D Hutchins; Douglas E Peterson
Journal:  Cancer       Date:  2007-03-01       Impact factor: 6.860

10.  Biomarkers of chemotherapy-induced diarrhoea: a clinical study of intestinal microbiome alterations, inflammation and circulating matrix metalloproteinases.

Authors:  Andrea M Stringer; Noor Al-Dasooqi; Joanne M Bowen; Thean H Tan; Maryam Radzuan; Richard M Logan; Bronwen Mayo; Dorothy M K Keefe; Rachel J Gibson
Journal:  Support Care Cancer       Date:  2013-02-10       Impact factor: 3.603
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  7 in total

1.  Featured Article: Nanoenhanced matrix metalloproteinase-responsive delivery vehicles for disease resolution and imaging.

Authors:  Donald A McCarthy; Ahmad A Nazem; James McNeilan; Nicole L Shakerley; Ryan R Clark; María D Idelchik; Mehmet Yigit; J Andrés Melendez
Journal:  Exp Biol Med (Maywood)       Date:  2016-07-29

2.  DNMT3b SUMOylation Mediated MMP-2 Upregulation Contribute to Paclitaxel Induced Neuropathic Pain.

Authors:  Han Wang; Yi-Jia Shen; Xiu-Juan Li; Jun Xia; Li Sun; Yehao Xu; Yu Ma; Dai Li; Yuan-Chang Xiong
Journal:  Neurochem Res       Date:  2021-02-06       Impact factor: 3.996

3.  Protective effect of homogeneous polysaccharides of Wuguchong (HPW) on intestinal mucositis induced by 5-fluorouracil in mice.

Authors:  Peng Shi; Tianqi Zhao; Wendong Wang; Fangli Peng; Ting Wang; Yong Jia; Linxuan Zou; Peng Wang; Simengge Yang; Yue Fan; Junwei Zong; Xueling Qu; Shouyu Wang
Journal:  Nutr Metab (Lond)       Date:  2022-05-18       Impact factor: 4.654

4.  Adrenomedullin protects rat dorsal root ganglion neurons against doxorubicin-induced toxicity by ameliorating oxidative stress.

Authors:  Amir Mahmoodazdeh; Sayed Mohammad Shafiee; Mohsen Sisakht; Zahra Khoshdel; Mohammad Ali Takhshid
Journal:  Iran J Basic Med Sci       Date:  2020-09       Impact factor: 2.699

5.  Leukocyte Gene Expression and Plasma Concentration in Multiple Sclerosis: Alteration of Transforming Growth Factor-βs, Claudin-11, and Matrix Metalloproteinase-2.

Authors:  Gholamreza Hassanzadeh; Samaneh Hosseini Quchani; Mohammad Ali Sahraian; Farid Abolhassani; Mohammad Ali Sadighi Gilani; Masoomeh Dehghan Tarzjani; Fatemeh Atoof
Journal:  Cell Mol Neurobiol       Date:  2016-01-14       Impact factor: 5.046

6.  Estrogen Enhances Esophageal Barrier Function by Potentiating Occludin Expression.

Authors:  Junya Honda; Katsunori Iijima; Kiyotaka Asanuma; Nobuyuki Ara; Takeharu Shiroki; Yutaka Kondo; Waku Hatta; Kaname Uno; Naoki Asano; Tomoyuki Koike; Tooru Shimosegawa
Journal:  Dig Dis Sci       Date:  2015-12-12       Impact factor: 3.199

7.  Tight junction defects are seen in the buccal mucosa of patients receiving standard dose chemotherapy for cancer.

Authors:  Hannah R Wardill; Richard M Logan; Joanne M Bowen; Ysabella Z A Van Sebille; Rachel J Gibson
Journal:  Support Care Cancer       Date:  2015-10-06       Impact factor: 3.603
  7 in total

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