OBJECTIVES: This study seeks to evaluate assessment of geriatric frailty and nutritional status in predicting postoperative mortality in gastric cancer surgery. METHODS: Preoperatively, patients operated for gastric adenocarcinoma underwent assessment of Groningen Frailty Indicator (GFI) and Short Nutritional Assessment Questionnaire (SNAQ). We studied retrospectively whether these scores were associated with in-hospital mortality. RESULTS: From 2005 to September 2012 180 patients underwent surgery with an overall mortality of 8.3%. Patients with a GFI ≥ 3 (n = 30, 24%) had a mortality rate of 23.3% versus 5.2% in the lower GFI group (OR 4.0, 95%CI 1.1-14.1, P = 0.03). For patients who underwent surgery with curative intent (n = 125), this was 27.3% for patients with GFI ≥ 3 (n = 22, 18%) versus 5.7% with GFI < 3 (OR 4.6, 95% CI 1.0-20.9, P = 0.05). SNAQ ≥ 1 (n = 98, 61%) was associated with a mortality rate of 13.3% versus 3.2% in patients with SNAQ =0 (OR 5.1, 95% CI 1.1-23.8, P = 0.04). Given odds ratios are corrected in multivariate analyses for age, neoadjuvant chemotherapy, type of surgery, tumor stage and ASA classification. CONCLUSIONS: This study shows a significant relationship between gastric cancer surgical mortality and geriatric frailty as well as nutritional status using a simple questionnaire. This may have implications in preoperative decision making in selecting patients who optimally benefit from surgery.
OBJECTIVES: This study seeks to evaluate assessment of geriatric frailty and nutritional status in predicting postoperative mortality in gastric cancer surgery. METHODS: Preoperatively, patients operated for gastric adenocarcinoma underwent assessment of Groningen Frailty Indicator (GFI) and Short Nutritional Assessment Questionnaire (SNAQ). We studied retrospectively whether these scores were associated with in-hospital mortality. RESULTS: From 2005 to September 2012 180 patients underwent surgery with an overall mortality of 8.3%. Patients with a GFI ≥ 3 (n = 30, 24%) had a mortality rate of 23.3% versus 5.2% in the lower GFI group (OR 4.0, 95%CI 1.1-14.1, P = 0.03). For patients who underwent surgery with curative intent (n = 125), this was 27.3% for patients with GFI ≥ 3 (n = 22, 18%) versus 5.7% with GFI < 3 (OR 4.6, 95% CI 1.0-20.9, P = 0.05). SNAQ ≥ 1 (n = 98, 61%) was associated with a mortality rate of 13.3% versus 3.2% in patients with SNAQ =0 (OR 5.1, 95% CI 1.1-23.8, P = 0.04). Given odds ratios are corrected in multivariate analyses for age, neoadjuvant chemotherapy, type of surgery, tumor stage and ASA classification. CONCLUSIONS: This study shows a significant relationship between gastric cancer surgical mortality and geriatric frailty as well as nutritional status using a simple questionnaire. This may have implications in preoperative decision making in selecting patients who optimally benefit from surgery.
Authors: Ab A Aaldriks; Lydia G M van der Geest; Erik J Giltay; Saskia le Cessie; Johanneke E A Portielje; Bea C Tanis; Johan W R Nortier; Ed Maartense Journal: J Geriatr Oncol Date: 2013-04-30 Impact factor: 3.599
Authors: R A Pol; B L van Leeuwen; L Visser; G J Izaks; J J A M van den Dungen; I F J Tielliu; C J Zeebregts Journal: Eur J Vasc Endovasc Surg Date: 2011-07-31 Impact factor: 7.069
Authors: V E P P Lemmens; K Bosscha; G van der Schelling; S Brenninkmeijer; J W W Coebergh; I H J T de Hingh Journal: Br J Surg Date: 2011-06-29 Impact factor: 6.939
Authors: L V van de Poll-Franse; V E P P Lemmens; J A Roukema; J W W Coebergh; G A P Nieuwenhuijzen Journal: Br J Surg Date: 2011-04-20 Impact factor: 6.939
Authors: M W J M Wouters; H E Karim-Kos; S le Cessie; B P L Wijnhoven; L P S Stassen; W H Steup; H W Tilanus; R A E M Tollenaar Journal: Ann Surg Oncol Date: 2009-04-16 Impact factor: 5.344
Authors: Travis A Shutt; Prejesh Philips; Charles R Scoggins; Kelly M McMasters; Robert C G Martin Journal: J Gastrointest Surg Date: 2016-01-25 Impact factor: 3.452