Literature DB >> 24418764

Rheumatoid arthritis in 2013. Translational medicine in RA: time for change.

Pierre Miossec1.   

Abstract

With every passing year, research on the pathogenesis of rheumatoid arthritis benefits from discoveries in other scientific fields. Three of the best examples that illustrate the benefit of such interdisciplinary bridges and the effects they have on our understanding of rheumatoid arthritis are presented here.

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Year:  2014        PMID： 24418764     DOI： 10.1038/nrrheum.2013.204

Source DB:  PubMed          Journal:  Nat Rev Rheumatol        ISSN： 1759-4790            Impact factor:   20.543


  10 in total

1.  Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.

Authors:  Estelle Bettelli; Yijun Carrier; Wenda Gao; Thomas Korn; Terry B Strom; Mohamed Oukka; Howard L Weiner; Vijay K Kuchroo
Journal:  Nature       Date:  2006-04-30       Impact factor: 49.962

2.  FOXO in the hole: leveraging GWAS for outcome and function.

Authors:  Peter K Gregersen; Nataly Manjarrez-Orduño
Journal:  Cell       Date:  2013-09-26       Impact factor: 41.582

Review 3.  Targeting IL-17 and TH17 cells in chronic inflammation.

Authors:  Pierre Miossec; Jay K Kolls
Journal:  Nat Rev Drug Discov       Date:  2012-10       Impact factor: 84.694

Review 4.  Biomarkers and personalised medicine in rheumatoid arthritis: a proposal for interactions between academia, industry and regulatory bodies.

Authors:  P Miossec; C L Verweij; L Klareskog; C Pitzalis; A Barton; F Lekkerkerker; S Reiter; A Laslop; F Breedveld; E Abadie; B Flamion; W Dere; S Mpofu; N Goel; D Ethgen; B Mitlak; S Ormarsdóttir; R Rao; Y Tsouderos; J-Y Reginster
Journal:  Ann Rheum Dis       Date:  2011-07-22       Impact factor: 19.103

5.  Genomic responses in mouse models poorly mimic human inflammatory diseases.

Authors:  Junhee Seok; H Shaw Warren; Alex G Cuenca; Michael N Mindrinos; Henry V Baker; Weihong Xu; Daniel R Richards; Grace P McDonald-Smith; Hong Gao; Laura Hennessy; Celeste C Finnerty; Cecilia M López; Shari Honari; Ernest E Moore; Joseph P Minei; Joseph Cuschieri; Paul E Bankey; Jeffrey L Johnson; Jason Sperry; Avery B Nathens; Timothy R Billiar; Michael A West; Marc G Jeschke; Matthew B Klein; Richard L Gamelli; Nicole S Gibran; Bernard H Brownstein; Carol Miller-Graziano; Steve E Calvano; Philip H Mason; J Perren Cobb; Laurence G Rahme; Stephen F Lowry; Ronald V Maier; Lyle L Moldawer; David N Herndon; Ronald W Davis; Wenzhong Xiao; Ronald G Tompkins
Journal:  Proc Natl Acad Sci U S A       Date:  2013-02-11       Impact factor: 11.205

6.  Phosphorylation of FOXP3 controls regulatory T cell function and is inhibited by TNF-α in rheumatoid arthritis.

Authors:  Hong Nie; Yingxia Zheng; Runsheng Li; Taylor B Guo; Dongyi He; Lei Fang; Xuebin Liu; Lianbo Xiao; Xi Chen; Bing Wan; Y Eugene Chin; Jingwu Z Zhang
Journal:  Nat Med       Date:  2013-02-10       Impact factor: 53.440

7.  FoxO3a involved in neutrophil and T cell survival is overexpressed in rheumatoid blood and synovial tissue.

Authors:  Fanny Turrel-Davin; Anne Tournadre; Alexandre Pachot; Béatrice Arnaud; Marie-Angélique Cazalis; Bruno Mougin; Pierre Miossec
Journal:  Ann Rheum Dis       Date:  2009-05-11       Impact factor: 19.103

8.  Th17 cells are restrained by Treg cells via the inhibition of interleukin-6 in patients with rheumatoid arthritis responding to anti-tumor necrosis factor antibody therapy.

Authors:  Jenny L McGovern; Dao X Nguyen; Clare A Notley; Claudia Mauri; David A Isenberg; Michael R Ehrenstein
Journal:  Arthritis Rheum       Date:  2012-10

9.  Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway.

Authors:  Saba Alzabin; Sonya M Abraham; Taher E Taher; Andrew Palfreeman; Dobrina Hull; Kay McNamee; Ali Jawad; Ejaz Pathan; Anne Kinderlerer; Peter C Taylor; Richard Williams; Rizgar Mageed
Journal:  Ann Rheum Dis       Date:  2012-05-01       Impact factor: 19.103

10.  Human SNP links differential outcomes in inflammatory and infectious disease to a FOXO3-regulated pathway.

Authors:  James C Lee; Marion Espéli; Carl A Anderson; Michelle A Linterman; Joanna M Pocock; Naomi J Williams; Rebecca Roberts; Sebastien Viatte; Bo Fu; Norbert Peshu; Tran Tinh Hien; Nguyen Hoan Phu; Emma Wesley; Cathryn Edwards; Tariq Ahmad; John C Mansfield; Richard Gearry; Sarah Dunstan; Thomas N Williams; Anne Barton; Carola G Vinuesa; Miles Parkes; Paul A Lyons; Kenneth G C Smith
Journal:  Cell       Date:  2013-09-12       Impact factor: 41.582
  10 in total
  1 in total

1.  Mesenchymal stem cells alleviate experimental rheumatoid arthritis through microRNA-regulated IκB expression.

Authors:  Xin Yan; Yurong Cen; Qin Wang
Journal:  Sci Rep       Date:  2016-06-29       Impact factor: 4.379
  1 in total

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