BACKGROUND: The aim of this study was to compare the efficacy of radiofrequency ablation vs. cryoablation in the treatment of early breast cancer. PATIENTS AND METHODS: 80 women (mean age 73 ± 5 years) with early breast cancer were retrospectively evaluated. 40 patients underwent cryoablation and 40 patients underwent radiofrequency ablation, both with sentinel lymph node excision. Tumor volume and histopatological data were compared by means of postprocedural 3.0-T magnetic resonance imaging (MRI). 30-45 days after the percutaneous ablation, all patients underwent surgical resection of the tumor. The mean follow-up was 18 months without any local recurrences. RESULTS: Both techniques allow good correlation with histopathological data. In 75 patients (93.8%) we observed complete necrosis; in 5 cases there was residual disease in the postprocedural MRI and postoperative histological examination. There was a good correlation between MRI volume and histologic samples. Cosmetic results were good in all patients but 2. CONCLUSION: Both percutaneous radiofrequency ablation and cryotherapy are minimally invasive techniques with a good clinical and cosmetic outcome in selected cases. MRI examination is an ideal method to assess breast neoplasms in terms of quality and quantity as well as residual tumor extent after percutaneous ablation. Cryotherapy is the preferred method because of the analgesic effect of freezing with better patients compliance.
BACKGROUND: The aim of this study was to compare the efficacy of radiofrequency ablation vs. cryoablation in the treatment of early breast cancer. PATIENTS AND METHODS: 80 women (mean age 73 ± 5 years) with early breast cancer were retrospectively evaluated. 40 patients underwent cryoablation and 40 patients underwent radiofrequency ablation, both with sentinel lymph node excision. Tumor volume and histopatological data were compared by means of postprocedural 3.0-T magnetic resonance imaging (MRI). 30-45 days after the percutaneous ablation, all patients underwent surgical resection of the tumor. The mean follow-up was 18 months without any local recurrences. RESULTS: Both techniques allow good correlation with histopathological data. In 75 patients (93.8%) we observed complete necrosis; in 5 cases there was residual disease in the postprocedural MRI and postoperative histological examination. There was a good correlation between MRI volume and histologic samples. Cosmetic results were good in all patients but 2. CONCLUSION: Both percutaneous radiofrequency ablation and cryotherapy are minimally invasive techniques with a good clinical and cosmetic outcome in selected cases. MRI examination is an ideal method to assess breast neoplasms in terms of quality and quantity as well as residual tumor extent after percutaneous ablation. Cryotherapy is the preferred method because of the analgesic effect of freezing with better patients compliance.
Authors: Guglielmo Manenti; Tommaso Perretta; Eleonora Gaspari; Chiara A Pistolese; Lia Scarano; Elsa Cossu; Elena Bonanno; Oreste C Buonomo; Giuseppe Petrella; Giovanni Simonetti; Salvatore Masala Journal: Eur Radiol Date: 2011-06-17 Impact factor: 5.315
Authors: Stijn van Esser; Maurice A A J van den Bosch; Paul J van Diest; Willem Th M Mali; Inne H M Borel Rinkes; Richard van Hillegersberg Journal: World J Surg Date: 2007-12 Impact factor: 3.352
Authors: I M C van der Ploeg; S van Esser; M A A J van den Bosch; W P Th M Mali; P J van Diest; I H M Borel Rinkes; R van Hillegersberg Journal: Eur J Surg Oncol Date: 2007-03-21 Impact factor: 4.424
Authors: Giovanni Mauri; Luca Maria Sconfienza; Lorenzo Carlo Pescatori; Maria Paola Fedeli; Marco Alì; Giovanni Di Leo; Francesco Sardanelli Journal: Eur Radiol Date: 2017-01-03 Impact factor: 5.315
Authors: Roberto Luigi Cazzato; Julien Garnon; Nitin Ramamurthy; Guillaume Koch; Georgia Tsoumakidou; Jean Caudrelier; Francesco Arrigoni; Luigi Zugaro; Antonio Barile; Carlo Masciocchi; Afshin Gangi Journal: Med Oncol Date: 2016-11-11 Impact factor: 3.064
Authors: Richard E Fine; Richard C Gilmore; Jill R Dietz; Susan K Boolbol; Michael P Berry; Linda K Han; Andrew S Kenler; Michael Sabel; Kenneth R Tomkovich; Noam A VanderWalde; Margaret Chen; Karen S Columbus; Lisa D Curcio; Sheldon M Feldman; Linsey Gold; Lydia Hernandez; Eric R Manahan; Susan A Seedman; Rashmi P Vaidya; Alexander B Sevrukov; Hussein D Aoun; Randy D Hicks; Rache M Simmons Journal: Ann Surg Oncol Date: 2021-08-15 Impact factor: 5.344