Metehan Gumus1, Hatice Gumus2, Sue E Jones3, Peter A Jones3, Ali R Sever4, Jennifer Weeks4. 1. Department of General Surgery, Dicle University, Medical School, Yenişehir, Diyarbakır, Turkey. 2. Department of Radiology, Dicle University, Medical School, Yenişehir, Diyarbakır, Turkey. 3. Department of Surgery, Maidstone Hospital, Hermitage Lane, Maidstone, United Kingdom. 4. Department of Radiology, Maidstone Hospital, Hermitage Lane, Maidstone, United Kingdom.
Abstract
BACKGROUND: Blue dye used for sentinel lymph node biopsy (SLNB) in breast cancer patients may cause prolonged skin discoloration at the site of injection. The aim of this study was to assess the duration of such skin discoloration. PATIENTS AND METHODS: 236 consecutive patients who had undergone breast conserving surgery and SLNB for breast cancer were reviewed prospectively from January 2007 to December 2009. RESULTS: Of the 236 patients, 2 had undergone bilateral surgery, and 41 had been examined in consecutive yearly reviews. Blue discoloration remained visible at the injection site after 12, 24, and > 36 months in 36.5, 23.6, and 8.6% of the patients, respectively. CONCLUSION: The use of patent blue for identification of the sentinel lymph node in patients undergoing breast cancer surgery may result in prolonged discoloration of the skin at the injection site.
BACKGROUND: Blue dye used for sentinel lymph node biopsy (SLNB) in breast cancerpatients may cause prolonged skin discoloration at the site of injection. The aim of this study was to assess the duration of such skin discoloration. PATIENTS AND METHODS: 236 consecutive patients who had undergone breast conserving surgery and SLNB for breast cancer were reviewed prospectively from January 2007 to December 2009. RESULTS: Of the 236 patients, 2 had undergone bilateral surgery, and 41 had been examined in consecutive yearly reviews. Blue discoloration remained visible at the injection site after 12, 24, and > 36 months in 36.5, 23.6, and 8.6% of the patients, respectively. CONCLUSION: The use of patent blue for identification of the sentinel lymph node in patients undergoing breast cancer surgery may result in prolonged discoloration of the skin at the injection site.
Authors: Sarah A McLaughlin; Mary J Wright; Katherine T Morris; Gladys L Giron; Michelle R Sampson; Julia P Brockway; Karen E Hurley; Elyn R Riedel; Kimberly J Van Zee Journal: J Clin Oncol Date: 2008-10-06 Impact factor: 44.544
Authors: Bo Yu; Shreya Goel; Dalong Ni; Paul A Ellison; Cerise M Siamof; Dawei Jiang; Liang Cheng; Lei Kang; Faquan Yu; Zhuang Liu; Todd E Barnhart; Qianjun He; Han Zhang; Weibo Cai Journal: Adv Mater Date: 2018-02-12 Impact factor: 30.849