Amino acid uptake and protein synthesis during early meiosis in Saccharomyces cerevisiae.

Uptake and incorporation into proteins of an externally supplied amino acid were followed during early meiosis in yeast. Under conditions optimal for development, an insufficient permeability of the cell leads to an incorporation pattern which reflects the changes in the activity of the amino acid transporting system rather than those in protein synthesis. A more correct picture of protein synthesis during early meiosis is obtained by the use of a mutant with an enhanced level of amino acid uptake.