Literature DB >> 24411725

Breaching the blood-brain barrier for drug delivery.

Robert D Bell1, Michael D Ehlers2.   

Abstract

Molecular "hitchhiking" through receptor-mediated transcytosis at the blood-brain barrier is a CNS drug delivery strategy. In this issue of Neuron, Niewoehner et al. (2014) describe a modular anti-transferrin receptor Fab approach for shuttling therapeutic antibodies into the brain.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24411725     DOI： 10.1016/j.neuron.2013.12.023

Source DB:  PubMed          Journal:  Neuron        ISSN： 0896-6273            Impact factor:   17.173


  13 in total

Review 1.  Targeting specific cells in the brain with nanomedicines for CNS therapies.

Authors:  Fan Zhang; Yi-An Lin; Sujatha Kannan; Rangaramanujam M Kannan
Journal:  J Control Release       Date:  2015-12-11       Impact factor: 9.776

Review 2.  Passive Immunotherapies for Central Nervous System Disorders: Current Delivery Challenges and New Approaches.

Authors:  Niyanta N Kumar; Michelle E Pizzo; Geetika Nehra; Brynna Wilken-Resman; Sam Boroumand; Robert G Thorne
Journal:  Bioconjug Chem       Date:  2018-10-24       Impact factor: 4.774

Review 3.  Strategies for delivering therapeutics across the blood-brain barrier.

Authors:  Georg C Terstappen; Axel H Meyer; Robert D Bell; Wandong Zhang
Journal:  Nat Rev Drug Discov       Date:  2021-03-01       Impact factor: 84.694

4.  Transferrin receptor-targeted theranostic gold nanoparticles for photosensitizer delivery in brain tumors.

Authors:  Suraj Dixit; Thomas Novak; Kayla Miller; Yun Zhu; Malcolm E Kenney; Ann-Marie Broome
Journal:  Nanoscale       Date:  2015-02-07       Impact factor: 7.790

Review 5.  Considerations When Developing Blood-Brain Barrier Crossing Drug Delivery Technology.

Authors:  Robert D Bell
Journal:  Handb Exp Pharmacol       Date:  2022

6.  Galectin-4-mediated transcytosis of transferrin receptor.

Authors:  Andres E Perez Bay; Ryan Schreiner; Ignacio Benedicto; Enrique J Rodriguez-Boulan
Journal:  J Cell Sci       Date:  2014-09-01       Impact factor: 5.285

7.  Brain uptake of multivalent and multi-specific DVD-Ig proteins after systemic administration.

Authors:  Denise Karaoglu Hanzatian; Annette Schwartz; Farid Gizatullin; Jamie Erickson; Kangwen Deng; Ruth Villanueva; Christopher Stedman; Cristina Harris; Tariq Ghayur; Andrew Goodearl
Journal:  MAbs       Date:  2018-06-05       Impact factor: 5.857

8.  Persistent prolate polymersomes for enhanced co-delivery of hydrophilic and hydrophobic drugs.

Authors:  Nicholas L'Amoreaux; Aon Ali; Shoaib Iqbal; Jessica Larsen
Journal:  Nanotechnology       Date:  2020-01-15       Impact factor: 3.953

9.  Oral Triphenylmethane Food Dye Analog, Brilliant Blue G, Prevents Neuronal Loss in APPSwDI/NOS2-/- Mouse Model.

Authors:  Jacob A Irwin; Alev Erisir; Inchan Kwon
Journal:  Curr Alzheimer Res       Date:  2016       Impact factor: 3.498

Review 10.  Nanotechnology Applications for Diffuse Intrinsic Pontine Glioma.

Authors:  Amy Lee Bredlau; Suraj Dixit; Chao Chen; Ann-Marie Broome
Journal:  Curr Neuropharmacol       Date:  2017       Impact factor: 7.363
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