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Literature DB >> 24396862

Modulation of raft domains in a lipid bilayer by boundary-active curcumin.

Manami Tsukamoto¹, Kenichi Kuroda, Ayyalusamy Ramamoorthy, Kazuma Yasuhara.

Abstract

The function and mode of action of curcumin in modulating the formation of lipid raft domains were investigated by microscopic observation using model membranes. Curcumin induces fusion of lipid raft domains at extremely low concentrations through the alteration of the boundary between the ordered and disordered phases.

Entities: Chemical Disease Species

Mesh：

Substances：
Lipid Bilayers
Curcumin

Year: 2014 PMID： 24396862 PMCID： PMC3947710 DOI： 10.1039/c3cc47738j

Source DB: PubMed Journal: Chem Commun (Camb) ISSN： 1359-7345 Impact factor: 6.222

21 in total

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Journal: Curr Opin Cell Biol Date: 2001-08 Impact factor: 8.382

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Authors: Michal A Surma; Christian Klose; Kai Simons
Journal: Biochim Biophys Acta Date: 2011-12-31

7. Curcumin stimulates cystic fibrosis transmembrane conductance regulator Cl- channel activity.

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9. Curcumin has potent anti-amyloidogenic effects for Alzheimer's beta-amyloid fibrils in vitro.

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10. Separation of liquid phases in giant vesicles of ternary mixtures of phospholipids and cholesterol.

Authors: Sarah L Veatch; Sarah L Keller
Journal: Biophys J Date: 2003-11 Impact factor: 4.033

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6. Discovery of a new function of curcumin which enhances its anticancer therapeutic potency.

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7. 10-Gingerol Targets Lipid Rafts Associated PI3K/Akt Signaling in Radio-Resistant Triple Negative Breast Cancer Cells.

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8. The Cytoprotective Role of Antioxidants in Mammalian Cells Under Rapidly Varying UV Conditions During Stratospheric Balloon Campaign.

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Journal: Front Pharmacol Date: 2019-08-02 Impact factor: 5.810

Review 9. Curcumin and Its Derivatives as Potential Therapeutic Agents in Prostate, Colon and Breast Cancers.

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10. NDS27 combines the effect of curcumin lysinate and hydroxypropyl-β-cyclodextrin to inhibit equine PKCδ and NADPH oxidase involved in the oxidative burst of neutrophils.

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